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Nicholls research centre research participants

Research focus

The main focus for clinical projects have the common theme of investigating neurohumoral aspects of common cardiovascular diseases including:

  • Myocardial infarction
  • Hypertension
  • Atrial fibrillation and
  • Heart failure

Participation in multi-centre trials of experimental treatments for these conditions is also part of our programme.

Some recent high profile publications from this team:

Adamson, P.D., McAllister, D.A., Pilbrow, A., Pickering, J.W., Poppe, K. K., Shah, A. S. V., Whalley, G.A., Ellis, C.J., Mills, N.L., Newby, D.E., Pemberton, C.J., Troughton, R., Doughty, R.N., Richards, A.M. (2019). Convalescent Troponin and Cardiovascular Death following Acute Coronary Syndrome. Heart Jul 23 pii: heartjnl-2019-315084. doi: 10.1136/heartjnl-2019-315084.

Scott, N.J.A., Rademaker, M.T., Charles, C.J., Espiner, E.A., Richards, A.M. (2019). Phosphodiesterase-9Inhibition: Integrated Hemodynamic, Hormonal and Renal Actions in Health and Experimental Heart Failure. J Am Coll Cardiol 74:889-901 doi: 10.1016/j.jacc.2019.05.067.

Lewis, L.K., Raudsepp, S.D., Prickett, T.C.R., Yandle, T.G., Doughty, R.N., Frampton, C.M., Pemberton, C.J., Richards, A.M. (2019). ProBNP that is Not Glycosylated at Threonine 71 is Decreased With Obesity in Patients with Heart Failure. Clin Chem 2019.302547. doi: 0.1373/clinchem.2019. 302547.

Wong, L.L., Zou, R., Zhou, L., Lim, J.Y., Yang, D.P.C., Liu, C., Chong, J.P.C., Ng, J.Y.X., Liew, O.W., Chan, S.P., Chen, Y.T., Chan, M.M.Y., Yeo, P.S.D., Ng, T.P., Ling, L.H., Sim, D., Leong, K.T.G., Ong, H.Y., Jaufeerally, F., Wong, R., Chai, P., Low, A.F., Lund, M., Devlin, G., Troughton, R., Cameron, V.A., Doughty, R.N., Lam, C.S.P., Too, H.P., Richards, A.M. (2019). Combining Circulating MicroRNA and NT-proBNP for Detecting Non-acute Heart Failure and Categorizing Heart Failure Subtype. J Am Coll Cardiol. 2019;7311:1300-1313.

Pickering, J.W., Young, J.M., Watson, A.S., George, P.M., Aldous, S.J., Troughton, R.W., Pemberton, C.J., Richards, A.M., Cullen, L.A., Than, M.P. (2018). Validity of a Novel Point-of-Care Troponin Assay for Single-Test Rule-Out of Acute Myocardial Infarction. JAMA Cardiol. Nov 1;3(11):1108-1112.

Than, M.P., Aldous, S.J., Troughton, R., Pemberton, C.J., Richards, A.M., Frampton, C.M.A., Florkowski, C.M., George, P.M., Bailey, S., Young, J.M., Cullen, L., Greenslade, J.H., Parsonage, W.A., Everett, B.M., Peacock, W.F., Jaffe, A.S., Pickering, J.W. (2018). Detectable high-sensitivity troponin within the population reference range conveys high 5-year cardiovascular risk: An observational study. Clin Chem 64:1044-1053. doi: 10.1373/clinchem.2017.285700.

Lam, C.S.P., Gamble, G.D., Ling, L.H., Sim, D., Leong, K.T.G., Yeo, P.S.D., Ong, H.Y., Jaufeerally, F., Ng, T.P., Cameron, V.A., Poppe, K., Lund, M., Devlin, G., Troughton, R., Richards, A.M., Doughty, R.N. (2018). Mortality Associated With Heart Failure With Preserved Versus Reduced Ejection Fraction In A Prospective International Multi-Ethnic Cohort Study. Eur Heart J 39: 1770-1780 doi:10.1093/ eurheartj /ehy005.

Senior academic and research staff

Scientist

Biostatistician

Research staff

  • Alieke Dierckx
  • Dr Charlotte Greer
  • Judy Heslop
  • Cindy Kim
  • Rakesh Mathal
  • Shannon Chen
  • Juhi Campbell

Research nurses

  • Ruth Jardine
  • Steph Rose
  • Rachel Sanders

Cardiac Sonographer

  • Laura Perston

Administrator

  • Liz Ridder

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