Research Associate Professor
Email anna.pilbrow@otago.ac.nz
Christchurch Heart Institute
Department of Medicine
University of Otago, Christchurch
PO Box 4345
Christchurch
New Zealand
Current roles
- Leader of the Omics Laboratory, Christchurch Heart Institute
- Deputy Head of Department, Medicine
Research interests
Cardiovascular Genetics
Anna completed her PhD at the University of Otago, Christchurch in 2006 and undertook postdoctoral training at the Salk Institute, La Jolla, California, USA from 2008–2010.
Since returning to Aotearoa in 2010, her research has focussed on understanding the mechanisms underlying our inherited susceptibility to heart disease. She has a particular interest in identifying molecules circulating in our blood that may signal the early stages of heart disease and contribute to a poor prognosis in heart patients.
Anna is currently leading a large international study to identify genetic variants that may influence progression from coronary artery disease to heart failure.
Awards
- University of Otago Christchurch Four Year Fellowship, 2023
- Heart Foundation of New Zealand Foundation100 Fellowship, 2021
- Finalist, Division of Health Sciences, Otago University Students’ Association Supervisor of the Year Award, 2020
- ThermoFisher Scientific Award for Excellence in Molecular Biology, Queenstown Research Week, 2017
- Heart Foundation of New Zealand Senior Fellowship, 2014
- University of Otago Early Career Award for Distinction in Research, 2014
- Sir Charles Hercus Health Research Fellowship, 2011
Affiliations
- Department of Medicine
- Christchurch Heart Institute
Publications
Gibbs, S. F. P., Jones, G. T., Cameron, V. A., Fakahau, T., Frampton, C., Earle, N. J., Poppe, K. K., … Troughton, R., Pilbrow, A. P., & Faatoese, A. F. (2024). Associations between DNA methylation and cigarette smoking in Pacific Peoples living in Aotearoa New Zealand. Proceedings of the 17th GeneMappers Conference. Retrieved from https://www.genemappersconference.org Conference Contribution - Published proceedings: Abstract
Ocariza, M. G. C., Paton, L. N., Tang, W. H. W., Templeton, E. M., Pilbrow, A. P., Pemberton, C. J., & Appleby, S. (2024). CNDP2 is a potential modulator of heart failure outcomes. Proceedings of the 17th GeneMappers Conference. Retrieved from https://www.genemappersconference.org Conference Contribution - Published proceedings: Abstract
Gibbs, S., Jones, G. T., Earle, N. J., Poppe, K. K., Cameron, V. A., Fakahau, P. T., Frampton, C., … Troughton, R., Pilbrow, A. P., & Fa'atoese, A. F. (2024). DNA methylation in the TXNIP gene is associated with type 2 diabetes in Pacific Peoples living in NZ. European Heart Journal, 45(Suppl. 1), ehae666.2750. doi: 10.1093/eurheartj/ehae666.2750 Journal - Research Article
Pilbrow, A. P., Tragante, V., Cameron, V. A., Jones, G. T., Helgadottir, A., Troughton, R. W., Richards, A. M., … Poppe, K. K. (2024). Predicting progression from coronary artery disease to heart failure in community cohorts. European Heart Journal, 45(Suppl. 1), ehae666.840. doi: 10.1093/eurheartj/ehae666.840 Conference Contribution - Published proceedings: Abstract
Deane, A., Myall, D., Pilbrow, A., Shoorangiz, R., Sharifzadeh-Kermani, A., Anderson, T., Dalrymple-Alford, J., … Melzer, T. (2024). Neurovascular involvement in Parkinson's disease (PD) cognitive impairment: A 4D flow study. Movement Disorders, 39(Suppl. 1), (pp. S480). doi: 10.1002/mds.29953 Conference Contribution - Published proceedings: Abstract
2024
Journal - Research Article
Gibbs, S., Jones, G. T., Earle, N. J., Poppe, K. K., Cameron, V. A., Fakahau, P. T., Frampton, C., … Troughton, R., Pilbrow, A. P., & Fa'atoese, A. F. (2024). DNA methylation in the TXNIP gene is associated with type 2 diabetes in Pacific Peoples living in NZ. European Heart Journal, 45(Suppl. 1), ehae666.2750. doi: 10.1093/eurheartj/ehae666.2750
Paterson, M. A., Pilbrow, A. P., Frampton, C. M. A., Cameron, V. A., Troughton, R. W., Pemberton, C. J., … Richards, A. M., … Palmer, B. R. (2024). Plasma soluble fms-like tyrosine kinase-1, placental growth factor, and vascular endothelial growth factor system gene variants as predictors of survival in heart failure. European Journal of Heart Failure. Advance online publication. doi: 10.1002/ejhf.3368
Greer, C. E., Chew-Harris, J., Adamson, P. D., Pemberton, C. J., Pickering, J. W., Pilbrow, A. P., Frampton, C. M., Troughton, R. W., Doughty, R. N., & Richards, A. M. (2024). Convalescent growth differentiation factor-15 and long-term outcomes after an acute coronary syndrome. Journal of Applied Laboratory Medicine, jfae032. Advance online publication. doi: 10.1093/jalm/jfae032
Journal - Research Other
Ocariza, M. G. C., Paton, L. N., Templeton, E. M., Pemberton, C. J., Pilbrow, A. P., & Appleby, S. (2024). CNDP2: An enzyme linking metabolism and cardiovascular diseases? Journal of Cardiovascular Translational Research. Advance online publication. doi: 10.1007/s12265-024-10560-4
Conference Contribution - Published proceedings: Abstract
Gibbs, S. F. P., Jones, G. T., Cameron, V. A., Fakahau, T., Frampton, C., Earle, N. J., Poppe, K. K., … Troughton, R., Pilbrow, A. P., & Faatoese, A. F. (2024). Associations between DNA methylation and cigarette smoking in Pacific Peoples living in Aotearoa New Zealand. Proceedings of the 17th GeneMappers Conference. Retrieved from https://www.genemappersconference.org
Ocariza, M. G. C., Paton, L. N., Tang, W. H. W., Templeton, E. M., Pilbrow, A. P., Pemberton, C. J., & Appleby, S. (2024). CNDP2 is a potential modulator of heart failure outcomes. Proceedings of the 17th GeneMappers Conference. Retrieved from https://www.genemappersconference.org
Pilbrow, A. P., Tragante, V., Cameron, V. A., Jones, G. T., Helgadottir, A., Troughton, R. W., Richards, A. M., … Poppe, K. K. (2024). Predicting progression from coronary artery disease to heart failure in community cohorts. European Heart Journal, 45(Suppl. 1), ehae666.840. doi: 10.1093/eurheartj/ehae666.840
Deane, A., Myall, D., Pilbrow, A., Shoorangiz, R., Sharifzadeh-Kermani, A., Anderson, T., Dalrymple-Alford, J., … Melzer, T. (2024). Neurovascular involvement in Parkinson's disease (PD) cognitive impairment: A 4D flow study. Movement Disorders, 39(Suppl. 1), (pp. S480). doi: 10.1002/mds.29953
Meza Alvarado, J. C., Page, R. A., Mallard, B. L., Bromhead, C., Pilbrow, A. P., Troughton, R. W., Frampton, C. M., Doughty, R. N., & Palmer, B. (2024). Vascular endothelial growth factor-A SNPs as predictors of hospitalisation for acute heart failure in patients with established coronary heart disease. European Journal of Heart Failure, 26(S2), (pp. 136). doi: 10.1002/ejhf.3326
Earle, N., Pilbrow, A., Poppe, K., Choi, Y., Logue, G., Devlin, G., … Richards, M., … Troughton, R., Cameron, V., … Doughty, R. (2024). Pharmacogenomic variation in antiplatelet and anticoagulant medication response: Data from the Multi-Ethnic New Zealand Study of Acute Coronary Syndromes. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S71). doi: 10.1016/j.hlc.2024.04.248
Pilbrow, A., Fa'atoese, A., & Pickering, J. (2024). Making small studies count: The need for more appropriate data analysis and guidelines to avoid reinforcing inequities. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S69). doi: 10.1016/j.hlc.2024.04.243
Gibbs, S., Jones, G., Cameron, V., Fakahau, P., Frampton, C., Earle, N., Poppe, K., Troughton, R., Pilbrow, A., & Fa'atoese, A. (2024). Epigenetic measures of 'biological ageing' associated with cardiovascular risk in non-Pacific populations do not predict cardiovascular risk in a cohort of Samoans, Tongans, and Fijians living in Aotearoa New Zealand. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S59-S60). doi: 10.1016/j.hlc.2024.04.222
Rolleston, A., Jones, G., Earle, N., Fitzgerald, S., Pilbrow, A., Poppe, K., … Cameron, V., … Doughty, R. (2024). Developing more precise and equitable cardiovascular disease risk prediction tools in Aotearoa. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S64). doi: 10.1016/j.hlc.2024.04.232
Greer, G., Chew-Harris, J., Adamson, P., Pemberton, C., Pickering, J., Pilbrow, A., Troughton, R., Doughty, R., Richards, M., & Frampton, C. (2024). Convalescent GDF-15 and long-term outcomes after acute coronary syndrome. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S74-S75). doi: 10.1016/j.hlc.2024.04.256
Ocariza, M., Paton, L., Tang, W., Templeton, E., Pilbrow, A., Pemberton, C., & Appleby, S. (2024). Investigating the role of carnosine dipeptidase II (CNDP2) in heart disease. Heart, Lung & Circulation, 33(Suppl. 2), (pp. S62). doi: 10.1016/j.hlc.2024.04.228
Harris, S. L., Jones, G. T., Pilbrow, A. P., Horwood, L. J., Martin, J., Frampton, C., Ip, W. T., Troughton, R. W., Greer, C., Yang, J., Epton, M. J., … Darlow, B. A., & Cameron, V. A. (2024). DNA methylation patterns at birth predict later-life health related pathobiology. Journal of Paediatrics & Child Health, 60(Suppl. 1), (pp. 107-108). doi: 10.1111/jpc.16526
2023
Journal - Research Article
Koh, H. W. L., Pilbrow, A. P., Tan, S. H., Zhao, Q., Benke, P. I., Burla, B., … Pickering, J. W., Troughton, R., Pemberton, C., … Richards, A. M., & Chan, M. Y. (2023). An integrated signature of extracellular matrix proteins and a diastolic function imaging parameter predicts post-MI long-term outcomes. Frontiers in Cardiovascular Medicine, 10, 1123682. doi: 10.3389/fcvm.2023.1123682
Templeton, E. M., Pilbrow, A. P., Kleffmann, T., Pickering, J. W., Rademaker, M. T., Scott, N. J. A., Ellmers, L. J., Charles, C. J., Endre, Z. H., Richards, A. M., Cameron, V. A., & Lassé, M. (2023). Comparison of SPEED, S-Trap, and in-solution-based sample preparation methods for mass spectrometry in kidney tissue and plasma. International Journal of Molecular Sciences, 24(7), 6290. doi: 10.3390/ijms24076290
Cameron, V. A., Jones, G. T., Horwood, L. J., Pilbrow, A. P., Martin, J., Frampton, C., Ip, W. T., Troughton, R. W., Greer, C., Yang, J., Epton, M. J., Harris, S. L., & Darlow, B. A. (2023). DNA methylation patterns at birth predict health outcomes in young adults born very low birthweight. Clinical Epigenetics, 15, 47. doi: 10.1186/s13148-023-01463-3
Earle, N. J., Poppe, K. K., Rolleston, A., Pilbrow, A., Aish, S., Bradbury, K., … Troughton, R. W., … Richards, A. M., Cameron, V. A., … Doughty, R. N. (2023). Prognostic modelling of clinical outcomes after first-time acute coronary syndrome in New Zealand. Heart, 109(14), 1088-1097. doi: 10.1136/heartjnl-2022-322010
Conference Contribution - Published proceedings: Abstract
Earle, N., Poppe, K., Pilbrow, A., Rolleston, A., Cameron, V., Logue, G., … Troughton, R., … Doughty, R. (2023). The prognostic value of cardiac troponin in a contemporary cohort of patients with first-time myocardial infarction. Heart, Lung & Circulation, 32(Suppl. 2), P10. doi: 10.1016/j.hlc.2023.04.231
Poppe, K., Doughty, R., Choi, Y., Devlin, G., Lund, M., Troughton, R., Richards, M., … Pilbrow, A. (2023). Assessing the accuracy of algorithms that predict ejection fraction for research in a cohort of patients with heart failure. Heart, Lung & Circulation, 32(Suppl. 2), P31. doi: 10.1016/j.hlc.2023.04.252
Conference Contribution - Verbal presentation and other Conference outputs
Meza-Alvarado, J. C., Page, R. A., Mallard, B., Bromhead, C., Pilbrow, A. P., Troughton, R. W., Frampton, C. M., … Richards, A. M., & Palmer, B. R. (2023, August). Vascular endothelial growth factor A polymorphisms impacting patient survival. Verbal presentation at the Queenstown Molecular Biology (QMB) Genomics Satellite, Queenstown, New Zealand.
2022
Journal - Research Article
Ward, Z., Schmeier, S., Pearson, J., Cameron, V. A., Frampton, C. M., Troughton, R. W., … Richards, A. M., & Pilbrow, A. P. (2022). Identifying candidate circulating RNA markers for coronary artery disease by deep RNA-sequencing in human plasma. Cell, 11, 3191. doi: 10.3390/cells11203191
Manandhar, S., Scott-Thomas, A., Harrington, M., Sinha, P., Pilbrow, A., Richards, A. M., Cameron, V., Bhatia, M., & Chambers, S. T. (2022). Hydrogen sulfide and substance P levels in patients with Escherichia coli and Klebsiella pneumoniae bacteraemia. International Journal of Molecular Sciences, 23, 8639. doi: 10.3390/ijms23158639
Wu, Z., Pilbrow, A. P., Liew, O. W., Chong, J. P. C., Sluyter, J., Lewis, L. K., Lasse, M., Frampton, C. M., … Cameron, V. A., … Richards, A. M. (2022). Circulating cardiac biomarkers improve risk stratification for incident cardiovascular disease in community dwelling populations. EBioMedicine, 82, 104170. doi: 10.1016/j.ebiom.2022.104170
Schillemans, T., Tragante, V., Maitusong, B., Gigante, B., Cresci, S., Laguzzi, F., … Richards, M., Pilbrow, A., Cameron, V., … Leander, K. (2022). Associations of polymorphisms in the peroxisome proliferator-activated receptor gamma coactivator-1 alpha gene with subsequent coronary heart disease: An individual-level meta-analysis. Frontiers in Physiology, 13, 909870. doi: 10.3389/fphys.2022.909870
Templeton, E. M., Lassé, M., Kleffmann, T., Ellmers, L. J., Palmer, S. C., Davidson, T., Scott, N. J. A., Pickering, J. W., Charles, C. J., Endre, Z. H., Cameron, V. A., Richards, A. M., Rademaker, M. T., & Pilbrow, A. P. (2022). Identifying candidate protein markers of acute kidney injury in acute decompensated heart failure. International Journal of Molecular Sciences, 23, 1009. doi: 10.3390/ijms23021009
Journal - Research Other
Tragante, V., Pilbrow, A., & Poppe, K. (2022). Improving early detection and risk prediction in heart failure. Frontiers in Cardiovascular Medicine, 9, 930935. doi: 10.3389/fcvm.2022.930935
Conference Contribution - Published proceedings: Abstract
Templeton, E., Lassé, M., Cameron, V., Pickering, J., Kleffmann, T., Hertzberg, D., Frampton, C., Ellmers, L., Palmer, S., … Scott, N., Charles, C., … Richards, M., … Troughton, R., Rademaker, M., & Pilbrow, A. (2022). Harnessing the power of 'Omics': Discovering novel microRNA and protein biomarkers of acute kidney injury in acute heart failure. Heart, Lung & Circulation, 31(Suppl. 2), (pp. S23-S24). doi: 10.1016/j.hlc.2022.05.009
Conference Contribution - Verbal presentation and other Conference outputs
Tragante, V., Poppe, K., Cameron, V. A., Jones, G. T., Frampton, C. M., Troughton, R. W., Richards, A. M., … Pilbrow, A. P. (2022, August). Predicting progression from coronary artery disease to heart failure. Verbal presentation at the Metabolic & Cardiovascular Disease Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
2021
Journal - Research Article
Ward, Z., Schmeier, S., Saddic, L., Sigurdsson, M. I., Cameron, V. A., Pearson, J., Miller, A., Morley-Bunker, A., … Pilbrow, A. P. (2021). Novel and annotated long noncoding RNAs associated with ischemia in the human heart. International Journal of Molecular Sciences, 22, 11324. doi: 10.3390/ijms222111324
Rademaker, M. T., Pilbrow, A. P., Ellmers, L. J., Palmer, S. C., Davidson, T., Mbikou, P., Scott, N. J. A., Permina, E., Charles, C. J., Endre, Z. H., & Richards, A. M. (2021). Acute decompensated heart failure and the kidney: Physiological, histological and transcriptomic responses to development and recovery. Journal of the American Heart Association, 10, e021312. doi: 10.1161/jaha.121.021312
Palmer, B. R., Paterson, M. A., Frampton, C. M., Pilbrow, A. P., Skelton, L., Pemberton, C. J., … Troughton, R. W., Richards, A. M., & Cameron, V. A. (2021). Vascular endothelial growth factor-A promoter polymorphisms, circulating VEGF-A and survival in acute coronary syndromes. PLoS ONE, 16(7), e0254206. doi: 10.1371/journal.pone.0254206
Schunk, S. J., Kleber, M. E., März, W., Pang, S., Zewinger, S., Triem, S., … Pilbrow, A. P., Richards, A. M., Cameron, V. A., … BIOS consortium. (2021). Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. European Heart Journal, 42, 1742-1756. doi: 10.1093/eurheartj/ehab107
Lassé, M., Pilbrow, A. P., Kleffmann, T., Andersson Överström, E., von Zychlinski, A., Frampton, C. M. A., … Troughton, R. W., Lewis, L. K., Prickett, T. C. R., Pemberton, C. J., Richards, A. M., & Cameron, V. A. (2021). Fibrinogen and hemoglobin predict near future cardiovascular events in asymptomatic individuals. Scientific Reports, 11(1), 4605. doi: 10.1038/s41598-021-84046-7
Stamp, L. K., Cameron, V. A., Woodfield, T. B. F., Walker, L., Currie, M., Templeton, E., Pilbrow, A. P., Tabakakis, K., Phillips, E., & Lim, K. S. (2021). Impact of COVID-19 on health research in New Zealand: A case study of a research-intensive campus. Journal of the Royal Society of New Zealand, 51(Suppl. 1), S75-S85. doi: 10.1080/03036758.2020.1867202
Templeton, E. M., Cameron, V. A., Pickering, J. W., Richards, A. M., & Pilbrow, A. P. (2021). Emerging microRNA biomarkers for acute kidney injury in acute decompensated heart failure. Heart Failure Reviews, 26, 1203-1217. doi: 10.1007/s10741-020-09928-w
Journal - Research Other
Ward, Z., Pearson, J., Schmeier, S., Cameron, V., & Pilbrow, A. (2021). Insights into circular RNAs: Their biogenesis, detection, and emerging role in cardiovascular disease. RNA Biology, 18(12), 2055-2072. doi: 10.1080/15476286.2021.1891393
2020
Journal - Research Article
Chan, M. Y., Efthymios, M., Tan, S. H., Pickering, J. W., Troughton, R., Pemberton, C., … Pilbrow, A., & Richards, A. M. (2020). Prioritizing candidates of post-myocardial infarction heart failure using plasma proteomics and single-cell transcriptomics. Circulation, 142, 1408-1421. doi: 10.1161/circulationaha.119.045158
Mahmoodi, B. K., Tragante, V., Kleber, M. E., Holmes, M. V., Schmidt, A. F., McCubrey, R. O., … Pilbrow, A. P., … Richards, A. M., … Cameron, V. A., … Patel, R. (2020). Association of factor V Leiden with subsequent atherothrombotic events: A GENIUS-CHD study of individual participant data. Circulation, 142, 546-555. doi: 10.1161/circulationaha.119.045526
Ellmers, L. J., Templeton, E. M., Pilbrow, A. P., Frampton, C., Ishii, I., Moore, P. K., Bhatia, M., Richards, A. M., & Cameron, V. A. (2020). Hydrogen sulfide treatment improves post-infarct remodeling and long-term cardiac function in CSE knockout and wild-type mice. International Journal of Molecular Sciences, 21(12), 4284. doi: 10.3390/ijms21124284
2019
Journal - Research Article
Adamson, P. D., McAllister, D., Pilbrow, A., Pickering, J. W., Poppe, K., Shah, A., Whalley, G., … Pemberton, C., Troughton, R. W., … Richards, A. M. (2019). Convalescent troponin and cardiovascular death following acute coronary syndrome. Heart, 105, 1717-1724. doi: 10.1136/heartjnl-2019-315084
Patel, R., Tragante, V., Schmidt, A. F., McCubrey, R. O., Holmes, M. V., Howe, L. J., … Pilbrow, A. P., … Richards, A. M., … Cameron, V. A., … Asselbergs, F. W. (2019). Subsequent event risk in individuals with established coronary heart disease: Design and rationale of the GENIUS-CHD Consortium. Circulation: Genomic & Precision Medicine, 12(4), 145-160. doi: 10.1161/CIRCGEN.119.002470
Patel, R. S., Schmidt, A. F., Tragante, V., McCubrey, R. O., Holmes, M. V., Howe, L. J., … Pilbrow, A. P., … Richards, A. M., … Cameron, V. A., … Asselbergs, F. W. (2019). Association of chromosome 9p21 with subsequent coronary heart disease events: A GENIUS-CHD study of individual participant data. Circulation: Genomic & Precision Medicine, 12(4), 161-172. doi: 10.1161/circgen.119.002471
Conference Contribution - Published proceedings: Abstract
Sock Hwee, T., Koh, H. W. L., Chua, J. Y., Yang, X. X., Ong, C. C., Teo, L., … Pilbrow, A. P., Pickering, J. W., Troughton, R. W., … Richards, A. M., & Chan, M. Y. (2019). Plasma proteomics identify plaque-related proteins that predict long-term recurrent coronary events in patients with acute coronary syndrome. European Heart Journal, 40(Suppl. 1), (pp. 3588). doi: 10.1093/eurheartj/ehz746.0660
2018
Journal - Research Article
Marks, E. C. A., Wilkinson, T. M., Frampton, C. M., Skelton, L., Pilbrow, A. P., Yandle, T. G., Pemberton, C. J., … Whalley, G. A., … Troughton, R. W., … Cameron, V. A., Richards, A. M., Gieseg, S. P., & Palmer, B. R. (2018). Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes. BMC Cardiovascular Disorders, 18, 169. doi: 10.1186/s12872-018-0894-1
Conference Contribution - Poster Presentation (not in published proceedings)
Mehta-Mujoo, P., Landmann, M., Pilbrow, A. P., Currie, M. J., Morrin, H. R., Hung, N. A., & Slatter, T. L. (2018, August). Visualisation of long non-coding RNA ANRIL in breast cancer. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2017
Journal - Research Article
Hu, Y.-J., Schmidt, A. F., Dudbridge, F., Holmes, M. V., Brophy, J. M., Tragante, V., … on behalf of the GENIUS-CHD Consortium, including Cameron, V. A., Pilbrow, A. P., & Richards, A. M. (2017). Impact of selection bias on estimation of subsequent event risk. Circulation: Cardiovascular Genetics, 10(5), e001616. doi: 10.1161/CIRCGENETICS.116.001616
Scott, N. J. A., Ellmers, L. J., Pilbrow, A. P., Thomsen, L., Richards, A. M., Frampton, C. M., & Cameron, V. A. (2017). Metabolic and blood pressure effects of walnut supplementation in a mouse model of the metabolic syndrome. Nutrients, 9, 722. doi: 10.3390/nu9070722
Zewinger, S., Kleber, M. E., Tragante, V., McCubrey, R. O., Schmidt, A. F., Direk, K., … Pilbrow, A. P., Cameron, V. A., Richards, A. M., … on behalf of the GENIUS-CHD consortium, … Speer, T. (2017). Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: A molecular and genetic association study. Lancet Diabetes & Endocrinology, 5(7), 534-543. doi: 10.1016/S2213-8587(17)30096-7
Conference Contribution - Verbal presentation and other Conference outputs
Pilbrow, A. P., Runesson, A. S. D., Sommer, M. A. W., Jones, G. T., Frampton, C. M., Pemberton, C. J., Troughton, R. W., Richards, A. M., & Cameron, V. A. (2017, September). Using microRNAs to predict heart disease events in the general population. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Pilbrow, A. P. (2017, September). Why heart disease runs in families. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2016
Journal - Research Article
Pilbrow, A. P., Lewis, K. A., Perrin, M. H., Sweet, W. E., Moravec, C. S., Tang, W. H. W., … Troughton, R. W., & Cameron, V. A. (2016). Cardiac CRFR1 expression is elevated in human heart failure and modulated by genetic variation and alternative splicing. Endocrinology, 157(12), 4865-4874. doi: 10.1210/en.2016-1448
Royds, J. A., Pilbrow, A. P., Morrin, H. R., Frampton, C., Russell, I. A., Moravec, C. S., … Currie, M. J., Hung, N. A., & Slatter, T. L. (2016). The rs11515 polymorphism is more frequent and associated with aggressive breast tumors with increased ANRIL and decreased p16INK4a expression. Frontiers in Oncology, 5, 306. doi: 10.3389/fonc.2015.00306
Conference Contribution - Verbal presentation and other Conference outputs
Pilbrow, A. (2016, March). Using microRNAs to predict heart disease events in the general population. Verbal presentation at the Genetics Otago Symposium, Dunedin, New Zealand.
2015
Journal - Research Article
Siriwardena, M., Pilbrow, A., Frampton, C., MacDonald, S. M., Wilkins, G. T., & Richards, A. M. (2015). Complications of intra-aortic balloon pump use: Does the final position of the IABP tip matter? Anaesthesia & Intensive Care, 43(1), 66-73.
Earle, N. J., Poppe, K. K., Pilbrow, A. P., Cameron, V. A., Troughton, R. W., Skinner, J. R., … Whalley, G. A., … Richards, A. M., & Doughty, R. N. (2015). Genetic markers of repolarization and arrhythmic events following acute coronary syndromes. American Heart Journal, 169(4), 579-586.e3. doi: 10.1016/j.ahj.2014.11.015
Journal - Research Other
Gupta, R. M., Pilbrow, A. P., & Weeke, P. E. (2015). Top advances in functional genomics and translational biology for 2014. Circulation: Cardiovascular Genetics, 8, 207-210. doi: 10.1161/CIRCGENETICS.115.001021
Conference Contribution - Published proceedings: Abstract
Wheeler, N. E., Cameron, V. A., Pearson, J. F., Gardener, P. T., Moravec, C. S., Sweet, W. E., … Troughton, R. W., Richards, A. M., & Pilbrow, A. P. (2015). Expression quantitative trait locus (eQTL) map for genetic variants associated with cardiovascular traits in human heart. Circulation, 132, A17027. [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Wheeler, N. E., Cameron, V. A., Pearson, J. F., Gardner, P. P., Moravec, C. S., Sweet, W. E., … Troughton, R. W., Richards, A. M., & Pilbrow, A. P. (2015, August-September). An expression quantitative trait locus (eQTL) map for human heart. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2014
Journal - Research Article
Cameron, V. A., & Pilbrow, A. P. (2014). Circulating microRNAs as biomarkers in coronary heart disease and heart failure. microRNA Diagnostics & Therapeutics, 1(1), 58-74.
Pilbrow, A. P., Cordeddu, L., Cameron, V. A., Frampton, C. M., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Yandle, T. G., Richards, A. M., & Foo, R. S.-Y. (2014). Circulating miR-323-3p and miR-652: Candidate markers for the presence and progression of acute coronary syndromes. International Journal of Cardiology, 176, 375-385. doi: 10.1016/j.ijcard.2014.07.068
Palmer, B. R., Slow, S., Ellis, K. L., Pilbrow, A. P., Skelton, L., Frampton, C. M., Palmer, S. C., Troughton, R. W., Yandle, T. G., … Whalley, G. A., … Lever, M., George, P. M., Chambers, S. T., … Richards, A. M., & Cameron, V. A. (2014). Genetic polymorphism rs6922269 in the MTHFD1L gene is associated with survival and baseline active vitamin B12 levels in post-acute coronary syndromes patients. PLoS ONE, 9(3), e89029. doi: 10.1371/journal.pone.0089029
Earle, N., Han, D. Y., Pilbrow, A., Crawford, J., Smith, W., Shelling, A. N., Cameron, V., … Skinner, J. R. (2014). Single nucleotide polymorphisms in arrhythmia genes modify the risk of cardiac events and sudden death in long QT syndrome. Heart Rhythm, 11(1), 76-82. doi: 10.1016/j.hrthm.2013.10.005
Journal - Research Other
Pilbrow, A. P., Arora, P., & Martinez-Fernandez, A. (2014). Top advances in functional genomics and translational biology for 2013. Circulation: Cardiovascular Genetics, 7(1), 89-92. doi: 10.1161/CIRCGENETICS.114.000521
Pilbrow, A. P. (2014). Discovery of an obesity susceptibility gene, KSR2, provides new insight into energy homeostasis pathways. Circulation: Cardiovascular Genetics, 7(2), 218-219. doi: 10.1161/CIRCGENETICS.114.000601
Pilbrow, A. P. (2014). Cardiac cell therapy in nonhuman primates: A significant step toward clinical translation. Circulation: Cardiovascular Genetics, 7(4), 565-566. doi: 10.1161/circgenetics.114.000800
Conference Contribution - Published proceedings: Abstract
Pilbrow, A. P., Frampton, C. M., Richards, A. M., Troughton, R. W., & Cameron, V. A. (2014). Elevated levels of circulating microRNA-223, microRNA-127 and microRNA-146a are associated with risk of near future cardiovascular events in asymptomatic individuals. Circulation, 130(Suppl. 2), A18066. [Abstract]
Pilbrow, A. P., Frampton, C. M., Richards, A. M., Troughton, R. W., & Cameron, V. A. (2014). Amino-terminal pro-brain natriuretic peptide improves risk stratification in asymptomatic individuals at very high risk of future cardiovascular events. Circulation, 130(Suppl. 2), A19648. [Abstract]
Cameron, V. A., Pilbrow, A. P., Ellis, K. L., Palmer, B. R., Troughton, R. W., & Richards, A. M. (2014). Duelling hormones: The renin-aldosterone system versus the natriuretic peptides in heart disease. Proceedings of the Medical Sciences Congress (MedSci). (pp. 15). Retrieved from http://www.physoc.org.nz/meetings/archive/medsci-2014-abstracts
Earle, N., Poppe, K., Cameron, V., Pilbrow, A., Troughton, R., Skinner, J., … Richards, M., & Doughty, R. (2014). Risk of sudden cardiac death following acute coronary syndromes: Interplay of single nucleotide polymorphisms and the presence of heart failure. Heart, Lung & Circulation, 23(Suppl. 2), (pp. e9). doi: 10.1016/j.hlc.2014.07.023
2013
Chapter in Book - Other
Richards, M., Troughton, R., Espiner, E., Cameron, V., Ellmers, L., Pilbrow, A., Charles, C., Rademaker, M., Pemberton, C., & Yandle, T. (2013). Christchurch Heart Institute. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 68-74). Christchurch, New Zealand: University of Otago.
Conference Contribution - Verbal presentation and other Conference outputs
Pilbrow, A. (2013, February). One man's trash is another man's treasure: Exploring 'junk DNA' in coronary artery disease. Verbal presentation at the Christchurch Medical School 40th Anniversary Celebrations, Christchurch, New Zealand.
2012
Journal - Research Article
Ellis, K. L., Pilbrow, A. P., Potter, H. C., Frampton, C. M., Doughty, R. N., Whalley, G. A., … Palmer, B. R., Skelton, L., Yandle, T. G., Troughton, R. W., Richards, A. M., & Cameron, V. A. (2012). Association between endothelin type A receptor haplotypes and mortality in coronary heart disease. Personalized Medicine, 9(3), 341-349. doi: 10.2217/PME.12.10
Pilbrow, A. P., Folkersen, L., Pearson, J. F., Brown, C. M., McNoe, L., Wang, N. M., … Black, M. A., Troughton, R. W., Richards, A. M., … Cameron, V. A. (2012). The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues. PLoS ONE, 7(6), e39574. doi: 10.1371/journal.pone.0039574
Ellis, K. L., Palmer, B. R., Frampton, C. M., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Pilbrow, A. P., Skelton, L., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2012). Genetic variation in the renin-angiotensin-aldosterone system is associated with cardiovascular risk factors and early mortality in established coronary heart disease. Journal of Human Hypertension, 27, 237-244. doi: 10.1038/jhh.2012.24
Conference Contribution - Published proceedings: Abstract
Cordeddu, L., Pilbrow, A. P., Cameron, V. A., Troughton, R. W., Richards, M. A., & Roger, S. (2012). Circulating miRNAs as biomarkers in acute coronary syndrome. Circulation Research, 111(4 Suppl. 1). [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Pilbrow, A. (2012, August). Non-coding RNA in coronary artery disease. Invited presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2011
Journal - Research Article
Ellis, K. L., Frampton, C. M., Pilbrow, A. P., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Skelton, L., Thomson, J. A., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2011). Genomic risk variants at 1p13.3, 1q41, and 3q22.3 are associated with subsequent cardiovascular outcomes in healthy controls and in established coronary artery disease. Circulation: Cardiovascular Genetics, 4(6), 636-646. doi: 10.1161/circgenetics.111.960336
Huising, M. O., Pilbrow, A. P., Matsumoto, M., van der Meulen, T., Park, H., Vaughan, J. M., … Vale, W. W. (2011). Glucocorticoids differentially regulate the expression of CRFR1 and CRFR2α in MIN6 insulinoma cells and rodent islets. Endocrinology, 152(1), 138-150. doi: 10.1210/en.2010-0791
Conference Contribution - Published proceedings: Abstract
Pilbrow, A. P., Pearson, J. F., McNoe, L., Ellis, K. L., Black, M. A., Sweet, W. E., … Troughton, R. W., Richards, A. M., … Cameron, V. A. (2011). Chromosome 1q41 and 3q22.3 coronary artery disease risk loci are associated with altered cardiac gene expression profiles in normal and diseased heart. Circulation, 124, A12170. [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Ellis, K. L., Frampton, C. M., Pilbrow, A. P., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Yandle, T. G., Richards, A. M., & Cameron, V. A. (2011, August). Genomic risk variants at 1p13.3, 1q41 and 3q22.3 are associated with subsequent cardiovascular outcomes in healthy controls and in patients with established coronary artery disease. Poster session presented at the European Society of Cardiology (ESC) Congress, Paris, France.
Ellis, K. L., Palmer, B. R., Pilbrow, A. P., Troughton, R. W., Doughty, R. N., Whalley, G. A., … Yandle, T. G., Richards, A. M., & Cameron, V. A. (2011, August). Genetic variation within the renin-angiotensin-aldosterone hormone system is associated with cardiovascular risk factors and subsequent readmission for non ST-elevation myocardial infarction. Poster session presented at the European Society of Cardiology (ESC) Congress, Paris, France.
Conference Contribution - Verbal presentation and other Conference outputs
Palmer, B. R., Ellis, K. L., Pilbrow, A. P., Slow, S., Lever, M., Palmer, S. C., Skelton, L., Frampton, C. M., Troughton, R. W., Yandle, T. G., … Chambers, S. T., George, P. M., Richards, A. M., & Cameron, V. A. (2011, September). Folate pathway genetics, homocysteine and survival in coronary heart patients. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Pilbrow, A. P., Pearson, J. F., Brown, C. M., McNoe, L., Sweet, W. E., Tang, W. H. W., Black, M. A., Troughton, R. W., Richards, A. M., … Cameron, V. A. (2011, September). Cardiac gene expression profiling. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2010
Journal - Research Article
Ellis, K. L., Pilbrow, A. P., Frampton, C. M., Doughty, R. N., Whalley, G. A., Ellis, C. J., Palmer, B. R., Skelton, L., Yandle, T. G., Palmer, S. C., Troughton, R. W., Richards, A. M., & Cameron, V. A. (2010). A common variant at chromosome 9P21.3 is associated with age of onset of coronary disease but not subsequent mortality. Circulation: Cardiovascular Genetics, 3(3), 286-293. doi: 10.1161/circgenetics.109.917443
Jarvis, M. D., Palmer, B. R., Pilbrow, A. P., Ellis, K. L., Frampton, C. M., Skelton, L., … Whalley, G. A., … Yandle, T. G., Richards, A. M., & Cameron, V. A. (2010). CYP1A1 MSPI (T6235C) gene polymorphism is associated with mortality in acute coronary syndrome patients. Clinical & Experimental Pharmacology & Physiology, 37(2), 193-198. doi: 10.1111/j.1440-1681.2009.05261.x
Lainchbury, J. G., Troughton, R. W., Strangman, K. M., Frampton, C. M., Pilbrow, A., Yandle, T. G., … Nicholls, M. G., & Richards, A. M. (2010). N-terminal pro-B-type natriuretic peptide-guided treatment for chronic heart failure: Results from the BATTLESCARRED (NT-proBNP-assisted treatment to lessen serial cardiac readmissions and death) trial. JACC, 55(1), 53-60. doi: 10.1016/j.jacc.2009.02.095
Conference Contribution - Published proceedings: Abstract
Pilbrow, A. P., Cameron, V. A., Lewis, K. A., Perrin, M. H., Sweet, W. E., Troughton, R. W., … Vale, W. W. (2010). Levels of cardiac corticotropin-releasing factor type 1 receptor gene expression are up-regulated in heart failure and altered in association with a large inversion polymorphism that spans the gene. Endocrine Reviews, 31(3, Suppl. 1), (pp. S1815). [Abstract]
2009
Journal - Research Article
Palmer, B. R., Devereaux, C. L., Dhamrait, S. S., Mocatta, T. J., Pilbrow, A. P., Frampton, C. M., Skelton, L., Yandle, T. G., Winterbourn, C. C., Richards, A. M., … Cameron, V. A. (2009). The common G-866A polymorphism of the UCP2 gene and survival in diabetic patients following myocardial infarction. Cardiovascular Diabetology, 8. doi: 10.1186/1475-2840-8-31
Conference Contribution - Published proceedings: Abstract
Cameron, V. A., Pilbrow, A. P., Palmer, B. R., Ellis, K. L., Pearson, J., Moravec, C. S., … Troughton, R. W., & Richards, A. M. (2009). Gene polymorphisms in patients with heart failure and acute coronary syndromes. CVD Prevention and Control. 4(Suppl. 1), (pp. S15). [Abstract]
Palmer, B. R., Ellis, K. L., Pilbrow, A. P., Skelton, L., Frampton, C. M., Troughton, R. W., Yandle, T. G., … Richards, A. M., & Cameron, V. A. (2009). Genetic polymorphism rs6922269 from the MTHFD1L gene predicts survival in patients after acute coronary syndromes. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Ellis, K. L., Pilbrow, A. P., Palmer, B. R., Frampton, C. M., Doughty, R. N., Ellis, C. J., Yandle, T. G., Troughton, R. W., Richards, A. M., & Cameron, V. A. (2009). A common variant at chromosome 9p21.3 is associated with age of onset of coronary disease but not subsequent mortality in coronary disease cohorts. European Heart Journal. 30(Suppl. 1), (pp. 63-64). doi: 10.1093/eurheartj/ehp416
Pilbrow, A. P., Pearson, J., Brown, C. M., McNoe, L., Black, M. A., Sweet, W. E., … Troughton, R. W., Richards, A. M., … Cameron, V. A. (2009). Chromosome 6q25.1 and 2q36.3 coronary heart disease risk loci are associated with altered cardiac gene expression profiles in normal heart. Circulation, 120(18, Suppl.), (pp. S564). [Abstract]
Film/Video/CD Rom
Fraser, R., Richards, M., Pilbrow, A., & Troughton, R. (2009). The Body, the Research, the Professor: Cardiac Research [Episode 3] [Film]. Christchurch, New Zealand: Canterbury Medical Research Foundation. Retrieved from http://www.cmrf.org.nz/Home/Videos/#vid1
2008
Journal - Research Article
Palmer, B. R., Pilbrow, A. P., Frampton, C. M., Yandle, T. G., Skelton, L., Nicholls, M. G., & Richards, A. M. (2008). Plasma aldosterone levels during hospitalization are predictive of survival post-myocardial infarction. European Heart Journal, 29, 2489-2496. doi: 10.1093/eurheartj/ehn383
Pilbrow, A. P., Ellmers, L. J., Black, M. A., Moravec, C. S., Sweet, W. E., Troughton, R. W., Richards, A. M., Frampton, C. M., & Cameron, V. A. (2008). Genomic selection of reference genes for real-time PCR in human myocardium. BMC Medical Genomics, 1, 64. doi: 10.1186/1755-8794-1-64
Ellmers, L. J., Scott, N. J. A., Medicherla, S., Pilbrow, A. P., Bridgman, P. G., Yandle, T. G., Richards, A. M., … Cameron, V. A. (2008). Transforming growth factor-β blockade down-regulates the renin-angiotensin system and modifies cardiac remodeling after myocardial infarction. Endocrinology, 149(11), 5828-5834. doi: 10.1210/en.2008-0165
Palmer, B. R., Jarvis, M. D., Pilbrow, A. P., Ellis, K. L., Frampton, C. M., Skelton, L., Yandle, T. G., … Whalley, G. A., … Troughton, R. W., Richards, A. M., & Cameron, V. A. (2008). Angiotensin-converting enzyme 2 A1075G polymorphism is associated with survival in an acute coronary syndromes cohort. American Heart Journal, 156(4), 752-758. doi: 10.1016/j.ahj.2008.06.013
Littlejohn, M. D., Palmer, B. R., Richards, A. M., Frampton, C. M., Pilbrow, A. P., Troughton, R. W., Cameron, V. A., & Kennedy, M. A. (2008). Ile164 variant of β2-adrenoceptor does not influence outcome in heart failure but may interact with β blocker treatment. European Journal of Heart Failure, 10(1), 55-59. doi: 10.1016/j.ejheart.2007.10.011
Molyneux, S. L., Florkowski, C. M., George, P. M., Pilbrow, A. P., Frampton, C. M., Lever, M., & Richards, A. M. (2008). Coenzyme Q10: An independent predictor of mortality in chronic heart failure. JACC, 52(18), 1435-1441. doi: 10.1016/j.jacc.2008.07.044
Conference Contribution - Published proceedings: Abstract
Palmer, B. R., Jarvis, M. D., Pilbrow, A. P., Frampton, C. M., Skelton, L., Littlejohn, M. D., Kennedy, M. A., … Yandle, T. G., Richards, A. M., & Cameron, V. A. (2008). Cardiovascular pharmacogenetics: Taking the opportunities. Proceedings of the 4th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.chmeds.ac.nz/research/carneycentre/symposium.htm
Siriwardena, M., Pilbrow, A., Richards, A. M., & Wilkins, G. T. (2008). Intra-aortic balloon counter-pulsation use at two tertiary referral centres in the South Island. Heart, Lung & Circulation, 17(Suppl. 2), (pp. S25-S26). doi: 10.1016/j.hlc.2008.03.059
Richards, A. M., Lainchbury, J. G., Troughton, R. W., Strangman, K., Frampton, C. M., Pilbrow, A., Yandle, T. G., Hamid, A., & Nicholls, M. G. (2008). NTproBNP guided treatment for chronic heart failure: Results from the Battlescarred Trial. Circulation, 118(18, Suppl.), (pp. 1035-1036). [Abstract]
Palmer, B. R., Pilbrow, A. P., Skelton, L., Ellis, K. L., Jarvis, M. D., Frampton, C. M., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2008). ACE gene polymorphisms, survival and natriuretic peptide profiles after acute coronary syndromes. Arquivos Brasileiros de Endocrinologia & Metabologia. (pp. S895-S896). [Abstract]
Irvine, J., Pilbrow, A., Frampton, C., Endre, Z., Richards, M., & Cameron, V. (2008). Early post transplant anaemia is not associated with the angiotensin II type 1 A1166C single nucleotide polymorphism or angiotensin converting enzyme insertin/deletion polymorphism in renal transplantation. Transplantation. 86(2S), (pp. 735). [Abstract]
Pilbrow, A., Pearson, J., McNoe, L., Black, M., Moravec, C., Sweet, W., … Troughton, R., Richards, M., & Cameron, V. (2008). The chromosome 9p21.3 coronary artery disease risk locus is associated with altered cardiac gene expression in individuals without overt cardiac abnormality. Circulation, 118(18, Suppl.), (pp. S_390-S_391). [Abstract]
Irvine, J. H., Pilbrow, A. P., Frampton, C. M., Richards, M. A., Endre, Z. H., & Cameron, V. A. (2008). Donor type and recipient angiotensin II type 1 receptor A1166C genotype may influence kidney transplant survival at 10 years. Journal of the American Society of Nephrology, 19(Abstracts Issue), (pp. 441A-442A). [Abstract]
Palmer, B. R., Jarvis, M. D., Pilbrow, A. P., Ellis, K. L., Frampton, C. M., Skelton, L., Yandle, T. G., … Troughton, R. W., Richards, A. M., & Cameron, V. A. (2008). Angiotensin-converting enzyme 2 gene variants and survival in an acute coronary syndromes cohort. New Zealand Medical Journal, 121(1271). Retrieved from http://journal.nzma.org.nz/journal/121-1271/2990/content.pdf
Ellis, K. L., Pilbrow, A. P., Skelton, L., Frampton, C. M., Yandle, T. G., Palmer, B. R., Gemmell, N. J., Richards, A. M., & Cameron, V. A. (2008). Prognostic neurohormone levels in acute coronary syndromes patients of New Zealand European, Maori and Pacific ancestry. New Zealand Medical Journal, 121(1271). Retrieved from http://journal.nzma.org.nz/journal/121-1271/2990/content.pdf
2007
Journal - Research Article
Pilbrow, A. P., Palmer, B. R., Frampton, C. M., Yandle, T. G., Troughton, R. W., Campbell, E., Skelton, L., Lainchbury, J. G., Richards, A. M., & Cameron, V. A. (2007). Angiotensinogen M235T and T174M gene polymorphisms in combination doubles the risk of mortality in heart failure. Hypertension, 49(2), 322-327.
Mocatta, T. J., Pilbrow, A. P., Cameron, V. A., Senthilmohan, R., Frampton, C. M., Richards, A. M., & Winterbourn, C. C. (2007). Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction. JACC, 49(20), 1993-2000. doi: 10.1016/j.jacc.2007.02.040
Conference Contribution - Published proceedings: Abstract
Ellis, K. L., Pilbrow, A. P., Skelton, L. Z., Frampton, C. M., Yandle, T. G., Palmer, B. R., Gemmell, N. J., Richards, A. M., & Cameron, V. A. (2007). Prognostic neurohormone levels in acute coronary syndromes patients of New Zealand European, Maori and Pacific ancestry. European Heart Journal. 28(Abstract Suppl.), (pp. 771). [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Ellmers, L. J., Scott, N. J. A., Protter, A. A., Medicherla, S., Pilbrow, A. P., Richards, A. M., & Cameron, V. A. (2007, November). Transforming growth factor-beta blockade down-regulates the renin-angiotensin system and modifies cardiac remodelling post-myocardial infarction. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.
Palmer, B. R., Pilbrow, A. P., Baird, T. E., Collins, R. P., Skelton, L. Z., Frampton, C. M., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2007, August). Genetic predictors of survival after acute myocardial infarction. Verbal presentation at the 17th Queenstown Molecular Biology Meeting, Queenstown, New Zealand.
Cameron, V. A., Pilbrow, A. P., Ellis, K. L., Jarvis, M. D., Palmer, B. R., Ellmers, L. J., Scott, N. J. A., Frampton, C. M., Troughton, R. W., & Richards, A. M. (2007, November). Big hearts, bad hearts: Deconstructing the distinction. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.
Pilbrow, A. P., Ellmers, L. J., Black, M., Sweet, W. E., Moravec, C. S., Troughton, R. W., Richards, A. M., & Cameron, V. A. (2007, November). Multiple reference genes are required for accurate normalisation of gene expression levels in human heart. Verbal presentation at the Medical Sciences Congress, Queenstown, New Zealand.
Pilbrow, A. P., Palmer, B. R., Frampton, C. M., Yandle, T. G., Troughton, R. W., Lainchbury, J. G., Richards, A. M., & Cameron, V. A. (2007, June). Angiotensinogen and angiotensin II Type I receptor gene polymorphisms interact to predict prognosis in heart failure patients. Verbal presentation at the Endocrine Society's 89th Annual Meeting, Toronto, Canada.
Ellis, K. L., Pilbrow, A. P., Skelton, L., Frampton, C. M., Yandle, T. G., Palmer, B. R., Gemmell, N. J., Richards, A. M., & Cameron, V. A. (2007, August). Prognostic neurohormone levels in acute coronary syndromes patients of New Zealand European, Maori and Pacific ancestry. Verbal presentation at the Canterbury Health Research Conference, Christchurch, New Zealand.
Palmer, B. R., Jarvis, M. D., Pilbrow, A. P., Ellis, K. L., Frampton, C. M., Skelton, L., Yandle, T. G., … Troughton, R. W., Richards, A. M., & Cameron, V. A. (2007, August). Angiotensin-converting enzyme 2 gene variants and survival in an acute coronary syndromes cohort. Verbal presentation at the Canterbury Health Research Conference, Christchurch, New Zealand.
Ellis, K. L., Pilbrow, A. P., Skelton, L. Z., Frampton, C. M., Yandle, T. G., Palmer, B. R., Gemmell, N. J., Richards, A. M., & Cameron, V. A. (2007, September). Prognostic neurohormone levels in acute coronary syndromes patients of New Zealand European, Maori and Pacific ancestry. Verbal presentation at the European Society of Cardiology Congress, Vienna, Austria.
2006
Journal - Research Article
Collins, R. P., Palmer, B. R., Pilbrow, A. P., Frampton, C. M., Troughton, R. W., Yandle, T. G., Skelton, L., Richards, A. M., & Cameron, V. A. (2006). Evaluation of AMPD1 C34T genotype as a predictor of mortality in heart failure and post-myocardial infarction patients. American Heart Journal, 152(2), 312-320.
Cameron, V. A., Mocatta, T. J., Pilbrow, A. P., Frampton, C. M., Troughton, R. W., Richards, A. M., & Winterbourn, C. C. (2006). Angiotensin type-1 receptor A1166C gene polymorphism correlates with oxidative stress levels in human heart failure. Hypertension, 47(6), 1155-1161.
Conference Contribution - Published proceedings: Abstract
Palmer, B. R., Robinson, J., Skelton, L., Frampton, C. M., Pilbrow, A. P., Troughton, R. W., Yandle, T. G., Richards, M., & Cameron, V. A. (2006). The Christchurch Cardioendocrine Research Group DNA Bank: Seeking improved prognostic markers for heart disease patients. Proceedings of the Australian Health and Medical Research Congress. (pp. 389). Sydney, Australia: Australian Health and Medical Research Congress. [Abstract]
Cameron, V. A., Pilbrow, A. P., Palmer, B. R., Mocatta, T. J., Frampton, C. M., Troughton, R. W., Richards, A. M., & Winterbourn, C. C. (2006). Oxidative stress levels in human heart disease are correlated with angiotensin type-1 receptor A1166C gene polymorphism. Proceedings of the New Zealand Society of Endocrinology Annual Meeting. NZSE. Retrieved from http://nzse.rsnz.org/NZSE%20Abstracts%202006.pdf
Pilbrow, A. P., Palmer, B. R., Frampton, C. M., Yandle, T. G., Troughton, R. W., Campbell, E., Skelton, L., Lainchbury, J. G., Richards, A. M., & Cameron, V. A. (2006). Association of angiotensinogen M235T and T174M gene polymorphisms with mortality in heart failure. New Zealand Medical Journal, 119(1231). Retrieved from http://journal.nzma.org.nz/journal/119-1231/1922/content.pdf
Palmer, B. R., Baird, T. E., Collins, R. P., Pilbrow, A. P., Skelton, L., Frampton, C. M., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2006). Genetic polymorphisms as predictors of clinical outcome after acute myocardial infarction. New Zealand Medical Journal, 119(1231). Retrieved from http://journal.nzma.org.nz/journal/119-1231/1922/content.pdf
Conference Contribution - Poster Presentation (not in published proceedings)
Pilbrow, A. P., Palmer, B. R., Frampton, C. M., Yandle, T. G., Troughton, R. W., Campbell, E., Skelton, L., Lainchbury, J. G., Richards, A. M., & Cameron, V. A. (2006, August-September). Angiotensinogen M235T and T174M gene polymorphisms in combination doubles the risk of mortality in heart failure. Poster session presented at the 16th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand.
Ellis, K. L., Palmer, B. R., Pilbrow, A. P., Cameron, V. A., & Richards, A. M. (2006, August-September). Angiotensinogen M235T and T174M gene variants are associated with myocardial infarction and predict mortality in an acute coronary syndromes cohort. Poster session presented at the 16th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand.
Palmer, B., Baird, T. E., Collins, R. P., Pilbrow, A. P., Frampton, C. M., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2006, September). Genetic polymorphisms as predictors of clinical outcome after acute myocardial infarction. Poster session presented at the World Congress of Cardiology, Barcelona, spain.
Conference Contribution - Verbal presentation and other Conference outputs
Cameron, V. A., Palmer, B. R., Pilbrow, A. P., Ellis, K., & Richards, A. M. (2006, August-September). Gattaca revisited: Are heart disease outcomes written in our genes? Verbal presentation at the 16th Annual Queenstown Molecular Biology Meeting, Queenstown, New Zealand.
Awarded Doctoral Degree
Pilbrow, A. P. (2006). Genetic variants of the angiotensin hormone system as risk factors for heart disease (PhD). University of Otago, Dunedin, New Zealand. 275p.
2005
Conference Contribution - Published proceedings: Abstract
Pilbrow, A. P., Palmer, B. R., Frampton, C. M., Yandle, T. G., Troughton, R. W., Campbell, E., Skelton, L., Lainchbury, J. G., Richards, A. M., & Cameron, V. A. (2005). The genetics of coronary heart disease. Proceedings of the Human Genetics Society of Australasia (NZ Branch) Biennial Scientific Meeting and Annual General Meeting. [Abstract]
Cameron, V. A., Pilbrow, A. P., Mocatta, T. J., Palmer, B. R., Frampton, C. M., Troughton, R. W., Richards, A. M., & Winterbourn, C. C. (2005). Elevated oxidative stress levels in heart disease and association with angiotensin receptor genotype. Proceedings of the Medical Sciences Congress. (pp. 39). [Abstract]
Pilbrow, A. P., Palmer, B. R., Frampton, C. M., Yandle, T. G., Troughton, R. W., Campbell, E., Skelton, L., Lainchbury, J. G., Richards, A. M., & Cameron, V. A. (2005). Association of angiotensinogen M235T and T174M gene polymorphisms with mortality in heart failure. Proceedings of the Canterbury Health Research Conference. (pp. 23). [Abstract]
Palmer, B. R., Baird, T. E., Collins, R. P., Pilbrow, A. P., Skelton, L., Frampton, C. M., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2005). Genetic polymorphisms as predictors of clinical outcome after acute myocardial infarction. Proceedings of the Canterbury Health Research Conference. (pp. 20). [Abstract]
2004
Conference Contribution - Published proceedings: Abstract
Cameron, V. A., Palmer, B. R., Pilbrow, A. P., Ellmers, L. J., Scott, N. J. A., Troughton, R. W., Frampton, C. M., Lainchbury, J. G., Yandle, T. G., & Richards, A. M. (2004). Prediction and protection in heart disease. Proceedings of the Medical Sciences Congress 2004. (pp. 27). [Abstract]
Pilbrow, A., Ellmers, L. J., Troughton, R. W., Palmer, B. R., Richards, A. M., Sweet, W., … Cameron, V. A. (2004). Gene expression and genotype in donor and end-stage heart failed myocardium. Proceedings of the Fourteenth Annual Queenstown Molecular Biology Meeting in conjunction with the New Zealand Society for Biochemistry and Molecular Biology. (A59). [Abstract]
Palmer, B. R., Pilbrow, A. P., Collins, R. P., Skelton, L., Frampton, C. M., Troughton, R. W., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2004). Genetic association studies of heart disease in New Zealand. Proceedings of the New Zealand Medical Sciences Congress. (pp. 72). [Abstract]
Palmer, B. R., Moran, S., McEwen, S., Skelton, L., Frampton, C. M., Pilbrow, A. P., … Troughton, R. W., Yandle, T. G., Richards, A. M., & Cameron, V. A. (2004). The Christchurch cardioendocrine research group DNA bank. Proceedings of the Australian Health and Medical Research Congress. (pp. 328). [Abstract]
2003
Journal - Research Article
Palmer, B. R., Pilbrow, A. P., Yandle, T. G., Frampton, C. M., Richards, A. M., Nicholls, M. G., & Cameron, V. A. (2003). Angiotensin-converting enzyme gene polymorphism interacts with left ventricular ejection fraction and brain natriuretic peptide levels to predict mortality after myocardial infarction. JACC, 41(5), 729-736. doi: 10.1016/S0735-1097(02)02927-3
Conference Contribution - Published proceedings: Abstract
Pilbrow, A. P., Palmer, B. R., Yandle, T. G., Frampton, C. M., Richards, A. M., Nicholls, M. G., & Cameron, V. A. (2003). Angiotensin II type I receptor gene polymorphism interacts with N-terminal brain natriuretic peptide levels to predict prognosis in heart failure patients. Proceedings of the Endocrine Society's 85th Annual Meeting. (pp. 451). Chevy Chase, MD, USA: The Endocrine Society Press. [Abstract]
Pilbrow, A. P., Palmer, B. R., Frampton, C. M., Yandle, T. G., Troughton, R. W., Campbell, E., Richards, A. M., Nicholls, M. G., & Cameron, V. A. (2003). AT1R gene polymorphism interacts with N-BNP levels to predict prognosis in heart-failure patients. New Zealand Medical Journal, 116(1174). Retrieved from http://journal.nzma.org.nz/journal/116-1174/443/content.pdf
Palmer, B. R., Pilbrow, A. P., Frampton, C. M., Yandle, T. G., Nicholls, M. G., Richards, A. M., & Cameron, V. A. (2003). Angiotensin type I receptor A1166C genotype is associated with left ventricular volume in a New Zealand Post-Myocardial infarction cohort. Circulation, 107(19), (pp. e184). [Abstract]
2002
Conference Contribution - Published proceedings: Abstract
Palmer, B. R., Pilbrow, A. P., Frampton, C. M., Yandle, T. G., Nicholls, M. G., Richards, A. M., & Cameron, V. A. (2002). ACE insertion/deletion genotype is associated with prognosis in a New Zealand post-myocardial infarction cohort. Circulation, 105(14), (pp. e101-e102). [Abstract]
2001
Conference Contribution - Published proceedings: Abstract
Pilbrow, A. P., Palmer, B. R., Frampton, C. M., Richards, A. M., & Cameron, A. V. (2001). ACE gene polymorphism is associated with prognosis following myocardial infarction. Proceedings of the Eleventh Annual Queenstown Molecular Biology Meeting. [Abstract]