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MB ChB(Otago) FRACP

Email john.fink@cdhb.govt.nz

Department of Neurology
Christchurch Hospital
Private Bag 4710
Christchurch
New Zealand

Current Roles

  • Clinical Senior Lecturer, Department of Medicine
  • Clinical Director, Department of Neurology, Christchurch Hospital

Research Interests

  • Acute Stroke Imaging and Reperfusion Therapies
  • Stroke Units

Top 10 Publications

  1. Campbell BCV, Mitchell PJ, Churilov L, Yassi N, Kleinig TJ, Dowling RJ, Yan B, Bush SJ, Dewey HM, Thijs V, Scroop R, Simpson M, Brooks M, Asadi H, Wu TY, Shah DG, Wijeratne T, Ang T, Miteff F, Levi CR, Rodrigues E, Zhao H, Salvaris P, Garcia-Esperon C, Bailey P, Rice H, de Villiers L, Brown H, Redmond K, Leggett D, Fink JN, Collecutt W, Wong AA, Muller C, Coulthard A, Mitchell K, Clouston J, Mahady K, Field D, Ma H, Phan TG, Chong W, Chandra RV, Slater LA, Krause M, Harrington TJ, Faulder KC, Steinfort BS, Bladin CF, Sharma G, Desmond PM, Parsons MW, Donnan GA, Davis SM; EXTEND-IA TNK Investigators. Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke. N Engl J Med. 2018 Apr 26;378(17):1573-1582. doi: 10.1056/NEJMoa1716405. PMID: 29694815.
  2. Campbell BCV, Mitchell PJ, Churilov L, Yassi N, Kleinig TJ, Dowling RJ, Yan B, Bush SJ, Thijs V, Scroop R, Simpson M, Brooks M, Asadi H, Wu TY, Shah DG, Wijeratne T, Zhao H, Alemseged F, Ng F, Bailey P, Rice H, de Villiers L, Dewey HM, Choi PMC, Brown H, Redmond K, Leggett D, Fink JN, Collecutt W, Kraemer T, Krause M, Cordato D, Field D, Ma H, O'Brien B, Clissold B, Miteff F, Clissold A, Cloud GC, Bolitho LE, Bonavia L, Bhattacharya A, Wright A, Mamun A, O'Rourke F, Worthington J, Wong AA, Levi CR, Bladin CF, Sharma G, Desmond PM, Parsons MW, Donnan GA, Davis SM; EXTEND-IA TNK Part 2 investigators. Effect of Intravenous Tenecteplase Dose on Cerebral Reperfusion Before Thrombectomy in Patients With Large Vessel Occlusion Ischemic Stroke: The EXTEND-IA TNK Part 2 Randomized Clinical Trial. JAMA. 2020 Feb 20;323(13):1257–65. doi: 10.1001/jama.2020.1511. Epub ahead of print. PMID: 32078683; PMCID: PMC7139271.
  3. Davis SM, Donnan GA, Parsons MW, Levi C, Butcher KS, Peeters A, Barber PA, Bladin C, De Silva DA, Byrnes G, Chalk JB, Fink JN, Kimber TE, Schultz D, Hand PJ, Frayne J, Hankey G, Muir K, Gerraty R, Tress BM, Desmond PM; EPITHET investigators. Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol. 2008 Apr;7(4):299-309.
  4. Thompson SG, Barber PA, Gommans JH, Cadilhac DA, Davis A, Fink JN, Harwood M, Levack W, McNaughton HK, Feigin VL, Abernethy V, Girvan J, Kim J, Denison H, Corbin M, Wilson A, Douwes J, Ranta A. Geographic Disparities in Stroke Outcomes and Service Access: A Prospective Observational Study. Neurology. 2022 May 27;99(4):e414–26. doi: 10.1212/WNL.0000000000200526. Epub ahead of print. PMID: 35623890; PMCID: PMC9421775.
  5. Zhong CS, Beharry J, Salazar D, Smith K, Withington S, Campbell BCV, Wilson D, Le Heron C, Mason D, Duncan R, Reimers J, Mein-Smith F, Diprose WK, Barber PA, Ranta A, Fink JN, Wu TY. Routine Use of Tenecteplase for Thrombolysis in Acute Ischemic Stroke. Stroke. 2021 Mar;52(3):1087-1090. doi: 10.1161/STROKEAHA.120.030859. Epub 2021 Feb 16. PMID: 33588597.
  6. Beharry J, Fink J, Colgan F, Laing A, Mann D, Collecutt W, Krauss M, Wu T. Endovascular Therapy for Ischemic Stroke Can Be Successfully Performed by Peripheral Vascular Interventionalists. J Vasc Interv Radiol. 2020 Dec;31(12):1978-1983. doi: 10.1016/j.jvir.2020.08.031. Epub 2020 Nov 10. PMID: 33187862.
  7. Senadeera SC, Palmer DG, Keenan R, Beharry J, Yuh Lim J, Hurrell MA, Mouthaan P, Fink JN, Wilson D, Lim A, Wu TY. Left Atrial Appendage Thrombus Detected During Hyperacute Stroke Imaging Is Associated With Atrial Fibrillation. Stroke. 2020 Dec;51(12):3760-3764. doi: 10.1161/STROKEAHA.120.030258. Epub 2020 Nov 9. PMID: 33161849.
  8. Beharry J, Waters MJ, Drew R, Fink JN, Wilson D, Campbell BCV, Parsons MW, Kleinig TJ, Wu TY. Dabigatran Reversal Before Intravenous Tenecteplase in Acute Ischemic Stroke. Stroke. 2020 May;51(5):1616-1619. doi: 10.1161/STROKEAHA.119.028327. Epub 2020 Mar 25. PMID: 32208845.
  9. Fink JN, Frampton CM, Lyden P, Lees KR; Virtual International Stroke Trials Archive Investigators. Does hemispheric lateralization influence functional and cardiovascular outcomes after stroke?: an analysis of placebo-treated patients from prospective acute stroke trials. Stroke. 2008 Dec;39(12):3335-40
  10. Fink, J.N., Selim, M., Kumar, S., Horkan, C., Linfante, I., Caplan, L.R., Schlaug, G. The stroke patient who woke up: clinical and radiological features, including diffusion and perfusion MRI. Stroke 33: 988-993 (2002)

Publications

Fridman, M. R., Thompson, S. G., Tyson, A., Barber, P. A., Davis, A., Wu, T., Fink, J., … Punter, M. N. M., & Ranta, A. (2024). Sex differences in stroke reperfusion therapy in Aotearoa (New Zealand). Internal Medicine Journal. Advance online publication. doi: 10.1111/imj.16318 Journal - Research Article

Denison, H. J., Corbin, M., Douwes, J., Thompson, S. G., Harwood, M., Davis, A., Fink, J. N., Barber, P. A., Gommans, J. H., … Levack, W., McNaughton, H., … Ranta, A. (2023). Ethnic differences in stroke outcomes in Aotearoa New Zealand: A national linkage study. International Journal of Stroke. Advance online publication. doi: 10.1177/17474930231164024 Journal - Research Article

Kim, J., Cadilhac, D. A., Thompson, S., Gommans, J., Davis, A., Barber, P. A., Fink, J., Harwood, M., Levack, W., … Ranta, A. (2023). Comparison of stroke care costs in urban and nonurban hospitals and its association with outcomes in New Zealand: A nationwide economic evaluation. Stroke, 54, 848-856. doi: 10.1161/STROKEAHA.122.040869 Journal - Research Article

Berry-Noronha, A., Myall, D., Hong, J. B., Collecutt, W., Krauss, M., Fink, J., … Chatterjee, A., … Le Heron, C., … Wu, T. Y., & Wilson, D. (2023). Clinical outcomes of delayed mechanical thrombectomy: Descriptive analysis and development of a screening tool. European Journal of Neurology, 30, 671-677. doi: 10.1111/ene.15658 Journal - Research Article

Dunphy, H., Garcia-Esperon, C., Hong, J. B., Manoczki, C., Wilson, D., Chew, B. L. A., Beharry, J., … Ranta, A., Fink, J. N., & Wu, T. Y. (2023). Endovascular thrombectomy for acute ischaemic stroke improves and maintains function in the very elderly: A multicentre propensity score matched analysis. European Stroke Journal, 8(1), 191-198. doi: 10.1177/23969873221145778 Journal - Research Article

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