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Karina O'ConnorResearch Fellow

MSc(Cant), PhD(Otago)

Email karina.oconnor@otago.ac.nz

Research interests

Dr Karina O'Connor is investigating a novel amyloid formation mechanism ignited by oxidation.

Publications

Heath, S. G., Gray, S. G., Hamzah, E., O'Connor, K. M., Bozonet, S. M., Botha, A. D., de Cordovez, P., Magon, N. J., Naughton, J. D., … Göbl, C. (2024). Amyloid formation and depolymerization of tumor suppressor p16INK4a are regulated by a thiol-dependent redox mechanism. Nature Communications, 15(1), 5535. doi: 10.1038/s41467-024-49581-7 Journal - Research Article

Goebl, C., Heath, S., O'Connor, K. M., Bozonet, S., Botha, A., Smith, B., Hamzah, E., … Sethi, A., & Morris, V. K. (2023, August). A novel amyloid formation mechanism: Oxidation-induced transition of the tumour suppressor protein p16 into amyloid fibrils. Verbal presentation at the 33rd Queenstown Molecular Biology Meeting (QMB), Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs

Morris, V. K., Heath, S. G., O'Connor, K. M., Bozonnet, S., Gray, S. G., Naughton, J. D., Magon, N. J., Smith, B. R., Botha, A. D., … Göbl, C. (2022, August). The tumour suppressor protein p16 forms amyloid structures. Verbal presentation at the Cancer Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand. Conference Contribution - Verbal presentation and other Conference outputs

O'Connor, K. (2022, August). Assessment of plasma risk markers for acute kidney injury in patients with acute decompensated heart failure using a multiplex immunoassay. Poster session presented at the Metabolic & Cardiovascular Disease Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand. Conference Contribution - Poster Presentation (not in published proceedings)

Das, A. B., Seddon, A. R., O'Connor, K. M., & Hampton, M. B. (2021). Regulation of the epigenetic landscape by immune cell oxidants. Free Radical Biology & Medicine, 170, 131-149. doi: 10.1016/j.freeradbiomed.2020.12.453 Journal - Research Article

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