Research Associate Professor
Email john.pearson@otago.ac.nz
Tel +64 3 364 3653
Background
- 2008 - Biostatistical consultant with the Otago University, Christchurch.
- 2006 - 2008 Statistical analyst then senior research statistician at Statistics New Zealand where I worked on economic surveys and strategic development
- 2001 - 2006 Bioinformatics statistician then senior statistician at Vialactia Biosciences (NZ) Ltd, where I worked on animal studies, microarray analysis and design, experimental design, genetics
- 1998 - 2001 Lecturer in statistics at the University of Auckland
- Member of the New Zealand Statistics Association.
Research Interests
- Microarrays
- Genetics
- Bioinformatics
- Statistical Computing
- Survey Methods
Publications
Phang, R., Pearson, J., McCombie, A., Waddell, O., & Frizelle, F. (2024). The incidence of early-onset adenocarcinomas in Aotearoa New Zealand: 2000-2020. ANZ Journal of Surgery, 94(Suppl. 1), GS091P. doi: 10.1111/ans.18951 Conference Contribution - Published proceedings: Abstract
Waddell, O., Pearson, J., McCombie, A., Marshall, H., Glyn, T., Purcell, R., Keenan, J., & Frizelle, F. (2024). The rising incidence of early onset colorectal cancer in Aotearoa New Zealand: Changing trends from 2000 to 2020. ANZ Journal of Surgery, 94(Suppl. 1), GS003. doi: 10.1111/ans.18951 Conference Contribution - Published proceedings: Abstract
Prickett, T. C. R., Espiner, E. A., & Pearson, J. F. (2024). Association of natriuretic peptides and receptor activity with cardio-metabolic health at middle age. Scientific Reports, 14, 9919. doi: 10.1038/s41598-024-60677-4 Journal - Research Article
Waddell, O., Pearson, J., McCombie, A., Marshall, H., Purcell, R., Keenan, J., Glyn, T., & Frizelle, F. (2024). The incidence of early onset colorectal cancer in Aotearoa New Zealand: 2000–2020. BMC Cancer, 24, 456. doi: 10.1186/s12885-024-12122-y Journal - Research Article
McKean, N. E., McMurray, C., Handley, R. R., McLaughlan, C., Rudiger, S. R., Kelly, J., … Pearson, J., … Snell, R. G. (2023). Sheep models of Alzheimer's disease. Proceedings of the Society for Neuroscience Annual Meeting. PSTR102.05/D70. Retrieved from https://www.sfn.org/ Conference Contribution - Published proceedings: Abstract
2024
Journal - Research Article
Prickett, T. C. R., Espiner, E. A., & Pearson, J. F. (2024). Association of natriuretic peptides and receptor activity with cardio-metabolic health at middle age. Scientific Reports, 14, 9919. doi: 10.1038/s41598-024-60677-4
Waddell, O., Pearson, J., McCombie, A., Marshall, H., Purcell, R., Keenan, J., Glyn, T., & Frizelle, F. (2024). The incidence of early onset colorectal cancer in Aotearoa New Zealand: 2000–2020. BMC Cancer, 24, 456. doi: 10.1186/s12885-024-12122-y
Conference Contribution - Published proceedings: Abstract
Phang, R., Pearson, J., McCombie, A., Waddell, O., & Frizelle, F. (2024). The incidence of early-onset adenocarcinomas in Aotearoa New Zealand: 2000-2020. ANZ Journal of Surgery, 94(Suppl. 1), GS091P. doi: 10.1111/ans.18951
Waddell, O., Pearson, J., McCombie, A., Marshall, H., Glyn, T., Purcell, R., Keenan, J., & Frizelle, F. (2024). The rising incidence of early onset colorectal cancer in Aotearoa New Zealand: Changing trends from 2000 to 2020. ANZ Journal of Surgery, 94(Suppl. 1), GS003. doi: 10.1111/ans.18951
2023
Journal - Research Article
Hock, B. D., Goddard, L., MacPherson, S. A., Strother, M., Gibbs, D., Pearson, J. F., & McKenzie, J. L. (2023). Levels and in vitro functional effects of circulating anti-hinge antibodies in melanoma patients receiving the immune checkpoint inhibitor pembrolizumab. PLoS ONE, 18(9), e0290793. doi: 10.1371/journal.pone.0290793
Sulit, A. K., Daigneault, M., Allen-Vercoe, E., Silander, O. K., Hock, B., McKenzie, J., Pearson, J., Frizelle, F. A., Schmeier, S., & Purcell, R. (2023). Bacterial lipopolysaccharide modulates immune response in the colorectal tumor microenvironment. npj Biofilms & Microbiomes, 9, 59. doi: 10.1038/s41522-023-00429-w
Sulit, A. K., Wilson, K., Pearson, J., Silander, O. K., Sampurno, S., Michael, M., … Frizelle, F., & Purcell, R. V. (2023). Human gene and microbial analyses in rectal cancer complete responses to radiotherapy. BJS Open, 7(3), zrad035. doi: 10.1093/bjsopen/zrad035
Leadbetter, R., MacAskill, M., Myall, D. J., Taylor, B. V., Joshi, P., NZMSPS group, including Pearson, J. F., Clarke, G., Abernethy, D. A., & Mason, D. F. (2023). Multiple sclerosis mortality in New Zealand: A nationwide prospective study. Journal of Neurology, Neurosurgery & Psychiatry. Advance online publication. doi: 10.1136/jnnp-2022-330582
Thompson, N., Gatenby, G., Waddell, O., Purcell, R., Keenan, J., Pearson, J. F., Frizelle, F., & Glyn, T. (2023). Early onset colorectal cancer in Canterbury, New Zealand. ANZ Journal of Surgery, 93, 2148-2154. doi: 10.1111/ans.18357
Amir, I., Thomson, B. J., Herrod, J., Souter, M. A., Mustard, J., Pearson, J. F., & Bird, P. (2023). The effect of universal newborn hearing screening on spoken language after cochlear implantation. Otology & Neurotology, 44(3), e133-e139. doi: 10.1097/MAO.0000000000003793
Lee, M. S., Thomas, A., Pearson, J. F., Purcell, R., Frizelle, F., & Glyn, T. (2023). Risk of colorectal cancer in patients with appendicitis over the age of 40 years. Colorectal Disease, 25, 624-630. doi: 10.1111/codi.16429
Johnson, J. S., Cote, A. C., Dobbyn, A., Sloofman, L. G., Xu, J., Cotter, L., … Eating Disorders Working Group of the Psychiatric Genomics Consortium, including Boden, J. M., Pearson, J. F., … Jordan, J., Kennedy, M., … Huckins, L. M. (2023). Mapping anorexia nervosa genes to clinical phenotypes. Psychological Medicine, 53, 2619-2633. doi: 10.1017/s0033291721004554
Journal - Research Other
Prickett, T. C. R., Pearson, J. F., Troughton, R. W., Kennedy, M. A., & Espiner, E. A. (2023). The predictive value of A, B, and C-type natriuretic peptides in people at risk of heart disease: Protocol for a longitudinal observational study. JMIR Research Protocols, 12, e37011. doi: 10.2196/37011
Conference Contribution - Published proceedings: Abstract
McKean, N. E., McMurray, C., Handley, R. R., McLaughlan, C., Rudiger, S. R., Kelly, J., … Pearson, J., … Snell, R. G. (2023). Sheep models of Alzheimer's disease. Proceedings of the Society for Neuroscience Annual Meeting. PSTR102.05/D70. Retrieved from https://www.sfn.org/
Lee, M. S., Pearson, J., Purcell, R., Frizelle, F., & Glyn, T. (2023). Risk of colorectal cancer in patients with appendicitis over the age of 40 years. ANZ Journal of Surgery, 93(Suppl. 1), (pp. 43). doi: 10.1111/ans.18394
Conference Contribution - Verbal presentation and other Conference outputs
Pearson, J., Waddell, O., McCombie, A., Marshall, H., Purcell, R., Keenan, J., Glyn, T., & Frizelle, F. (2023, November-December). The incidence of early-onset colorectal cancer in Aotearoa: 2000-2020. Verbal presentation at the International Biometric Society Australasian Region (IBS-AR) and the Statistical Ecology and Environmental Monitoring (SEEM) Joint Conference, Waitangi, New Zealand.
Morley-Bunker, A., Currie, M., Pearson, J., Mukundan, R., Gavruskin, A., Hemmings, C., Eglinton, T., & Walker, L. (2023, August). Utilisation of digital pathology and AI methods for the detection of MSI status in colorectal cancer. Verbal presentation at the 33rd Queenstown Molecular Biology Meeting (QMB), Queenstown, New Zealand.
Appleby, S., Sulit, A. K., Pemberton, C. J., Pearson, J. F., & Purcell, R. V. (2023, August). Circulating bacterial DNA as a prognostic marker for myocardial infarction. Verbal presentation at the 17th New Zealand Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2022
Journal - Research Article
Hitchman, L. M., Faatoese, A., Merriman, T. R., Miller, A. L., Liau, Y., Graham, O. E. E., Kee, P. S., Pearson, J. F., … Cameron, V. A., Kennedy, M. A., & Maggo, S. D. S. (2022). Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoples. Frontiers in Genetics, 13, 1016416. doi: 10.3389/fgene.2022.1016416
Ward, Z., Schmeier, S., Pearson, J., Cameron, V. A., Frampton, C. M., Troughton, R. W., … Richards, A. M., & Pilbrow, A. P. (2022). Identifying candidate circulating RNA markers for coronary artery disease by deep RNA-sequencing in human plasma. Cell, 11, 3191. doi: 10.3390/cells11203191
Hakkaart, C., Pearson, J. F., Marquart, L., Dennis, J., Wiggins, G. A. R., Barnes, D. R., Robinson, B. A., Mace, P. D., … Walker, L. C. (2022). Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers. Communications Biology, 5, 1061. doi: 10.1038/s42003-022-03978-6
Aitchison, A., Pearson, J. F., Purcell, R. V., Frizelle, F. A., & Keenan, J. I. (2022). Detection of Fusobacterium nucleatum DNA in primary care patient stool samples does not predict progression of colorectal neoplasia. PLoS ONE, 17(6), e0269541. doi: 10.1371/journal.pone.0269541
Noble, A. J., Pearson, J. F., Noble, A. D., Boden, J. M., Horwood, L. J., Kennedy, M. A., & Osborne, A. J. (2022). DNA methylation analysis using bisulphite-based amplicon sequencing of individuals exposed to maternal tobacco use during pregnancy, and offspring conduct problems in childhood and adolescence. Reproduction, Fertility & Development, 34(7), 540-548. doi: 10.1071/rd21108
Conference Contribution - Published proceedings: Abstract
Sulit, A., Daigneault, M., Allen-Vercoe, E., Silander, O., Hock, B., McKenzie, J., Pearson, J., Frizelle, F., … Purcell, R. (2022). Lipopolysaccharide from colorectal cancer-associated bacteria influence cytokine production in immune cells. Colorectal Disease, 24(Suppl. 1), (pp. 55-56). doi: 10.1111/codi.16048
Purcell, R., Sulit, A., Wilson, K., Michael, M., Pearson, J., Ramsey, R., … Frizelle, F. (2022). The tumour microbiome and response to radiotherapy in rectal cancer. Colorectal Disease, 24(Suppl. 1), (pp. 5). doi: 10.1111/codi.16048
Conference Contribution - Poster Presentation (not in published proceedings)
Hitchman, L. M., Faatoese, A., Merriman, T. R., Miller, A. L., Liau, Y., Graham, O. E. E., Kee, P. S., Pearson, J. F., … Cameron, V. A., Kennedy, M. A., & Maggo, S. D. S. (2022, August-September). Allelic diversity of the pharmacogene CYP2D6 in New Zealand Māori and Pacific peoples. Poster session presented at the 31st Queenstown Molecular Biology Meeting (QMB), Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Sulit, A. K., Pearson, J., Liu, W., Silander, O. K., Wilson, K., Heriot, A., Frizelle, F., & Purcell, R. (2022, August). Human gene and microbial analyses suggest immunotherapy-like mechanisms in complete response to radiotherapy in rectal cancer. Verbal presentation at the Cancer Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
Liau, Y., Maggo, S., Lehnert, K., Doogue, M. P., Scull, A., Miller, A. L., Pearson, J. F., & Kennedy, M. A. (2022, August-September). Genomic analysis of angiotensin converting enzyme inhibitor-induced angioedema. Verbal presentation at the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) NZ Annual Scientific Meeting, Queenstown, New Zealand.
2021
Journal - Research Article
Ward, Z., Schmeier, S., Saddic, L., Sigurdsson, M. I., Cameron, V. A., Pearson, J., Miller, A., Morley-Bunker, A., … Pilbrow, A. P. (2021). Novel and annotated long noncoding RNAs associated with ischemia in the human heart. International Journal of Molecular Sciences, 22, 11324. doi: 10.3390/ijms222111324
Mears, E. R., Handley, R. R., Grant, M. J., Reid, S. J., Day, B. J., Rudiger, S. R., … Pearson, J. F., … Snell, R. G. (2021). A multi-omic Huntington's disease transgenic sheep-model database for investigating disease pathogenesis. Journal of Huntington's Disease, 10, 423-434. doi: 10.3233/jhd-210482
Morley-Bunker, A. E., Wiggins, G. A. R., Currie, M. J., Morrin, H. R., Whitehead, M. R., Eglinton, T., Pearson, J., & Walker, L. C. (2021). RNAscope compatibility with image analysis platforms for the quantification of tissue-based colorectal cancer biomarkers in archival formalin-fixed paraffin-embedded tissue. Acta Histochemica, 123, 151765. doi: 10.1016/j.acthis.2021.151765
Ip, H. F., van der Laan, C. M., Krapohl, E. M. L., Brikell, I., Sánchez-Mora, C., Nolte, I. M., … Miller, A., … Boden, J., Pearson, J., Horwood, L. J., Kennedy, M., Poulton, R., … Boomsma, D. I. (2021). Genetic association study of childhood aggression across raters, instruments, and age. Translational Psychiatry, 11, 413. doi: 10.1038/s41398-021-01480-x
Wiggins, G. A. R., Black, M. A., Dunbier, A., Morley-Bunker, A. E., kConFab Investigators, Pearson, J. F., & Walker, L. C. (2021). Increased gene expression variability in BRCA1-associated and basal-like breast tumours. Breast Cancer Research & Treatment, 189, 363-375. doi: 10.1007/s10549-021-06328-y
Gatenby, G., Glyn, T., Pearson, J., Gearry, R., & Eglinton, T. (2021). The long-term incidence of dysplasia and colorectal cancer in a Crohn’s colitis population-based cohort. Colorectal Disease, 23, 2399-2406. doi: 10.1111/codi.15756
Wiggins, G. A. R., Black, M. A., Dunbier, A., Merriman, T. R., Pearson, J. F., & Walker, L. C. (2021). Variable expression quantitative trait loci analysis of breast cancer risk variants. Scientific Reports, 11(1), 7192. doi: 10.1038/s41598-021-86690-5
Nabais, M. F., Laws, S. M., Lin, T., Vallerga, C. L., Armstrong, N. J., Blair, I. P., … Anderson, T. J., … Kennedy, M., … Pearson, J., Pitcher, T. L., … McRae, A. F. (2021). Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biology, 22(1), 90. doi: 10.1186/s13059-021-02275-5
Sabel, C. E., Pearson, J. F., Mason, D. F., Willoughby, E., Abernethy, D., & Taylor, B. V. (2021). The latitude gradient for multiple sclerosis prevalence is established in the early lifecourse. Brain, 144, 2038-2046. doi: 10.1093/brain/awab104
Sinha, P., Cree, S. L., Miller, A. L., Pearson, J. F., & Kennedy, M. A. (2021). Transcriptional analysis of sodium valproate in a serotonergic cell line reveals gene regulation through both HDAC inhibition-dependent and independent mechanisms. Pharmacogenomics Journal, 21, 359-375. doi: 10.1038/s41397-021-00215-x
Noble, A. J., Pearson, J. F., Boden, J. M., Horwood, L. J., Gemmell, N. J., Kennedy, M. A., & Osborne, A. J. (2021). A validation of Illumina EPIC array system with bisulfite-based amplicon sequencing. PeerJ, 9, e10762. doi: 10.7717/peerj.10762
Lattimore, V., Parsons, M. T., Spurdle, A. B., Pearson, J., Lehnert, K., Sullivan, J., … Morrin, H., Robinson, B., & Walker, L. (2021). Under-ascertainment of breast cancer susceptibility gene carriers in a cohort of New Zealand female breast cancer patients. Breast Cancer Research & Treatment, 185, 583-590. doi: 10.1007/s10549-020-05986-8
Munn-Chernoff, M. A., Johnson, E. C., Chou, Y.-L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., … Boden, J. M., … Horwood, L. J., … Pearson, J. F., … Jordan, J., Kennedy, M. A., … Agrawal, A. (2021). Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addiction Biology, 26, e12880. doi: 10.1111/adb.12880
Journal - Research Other
Ward, Z., Pearson, J., Schmeier, S., Cameron, V., & Pilbrow, A. (2021). Insights into circular RNAs: Their biogenesis, detection, and emerging role in cardiovascular disease. RNA Biology, 18(12), 2055-2072. doi: 10.1080/15476286.2021.1891393
Conference Contribution - Published proceedings: Abstract
Noble, A. J., Pearson, J. F., Kennedy, M. A., Boden, J. M., Horwood, L. J., & Osborne, A. J. (2021). Does DNA methylation link the association between maternal tobacco use during pregnancy and altered offspring neurodevelopment. Proceedings of the 16th Congress of the Federation of Asian & Oceanic Biochemists & Molecular Biologists (FAOBMB). (pp. 292). Retrieved from https://www.faobmb2021.org
Conference Contribution - Verbal presentation and other Conference outputs
Pearson, J. (2021, November). Variance of variants. Verbal presentation at the University of Otago Biostatistics Symposium, Dunedin, New Zealand.
2020
Journal - Research Article
Porter, J. A., MacKenzie, K. E., Darlow, B. A., Pearson, J. F., & Day, A. S. (2020). A questionnaire-based assessment of gastrointestinal symptoms in children with type 1 diabetes mellitus. Translational Pediatrics, 9(6), 743-749. doi: 10.21037/tp-20-139
Johnson, E. C., Demontis, D., Thorgeirsson, T. E., Walters, R. K., Polimanti, R., Hatoum, A. S., … Boden, J., … Pearson, J. F., … Horwood, J., … Kennedy, M. A., … Agrawal, A. (2020). A large-scale genome-wide association study meta-analysis of cannabis use disorder. Lancet Psychiatry, 7, 1032-1045. doi: 10.1016/S2215-0366(20)30339-4
White, R., Nonis, M., Pearson, J. F., Burgess, E., Morrin, H. R., Pullar, J. M., Spencer, E., Vissers, M. C. M., Robinson, B. A., & Dachs, G. U. (2020). Low vitamin C status in patients with cancer is associated with patient and tumor characteristics. Nutrients, 12(8), 2338. doi: 10.3390/nu12082338
Taylor, W. S., Pearson, J., Miller, A., Schmeier, S., Frizelle, F. A., & Purcell, R. V. (2020). MinION sequencing of colorectal cancer tumour microbiomes: A comparison with amplicon-based and RNA-sequencing. PLoS ONE, 15(5), e0233170. doi: 10.1371/journal.pone.0233170
O'Grady, M., Clarke, L., Turner, G., Doogue, M., Purcell, R., Pearson, J., & Frizelle, F. (2020). Statin use and risk of acute diverticulitis: A population-based case-control study. Medicine, 99(20), e20264. doi: 10.1097/md.0000000000020264
Chittleborough, T. J., Gutlic, I., Pearson, J. F., Watson, A., Bhatti, L. A., Buchwald, P., … Wakeman, C., Eglinton, T., & Frizelle, F. (2020). Increasing incidence of young-onset colorectal carcinoma: A three-country population analysis. Diseases of the Colon & Rectum, 63, 903-910. doi: 10.1097/DCR.0000000000001631
Bryois, J., Skene, N. G., Folmann Hansen, T., Kogelman, L. J. A., Watson, H. J., Liu, Z., … Eating Disorders Working Group of the Psychiatric Genomics Consortium, including Boden, J., … Jordan, J., … Kennedy, M., … Pearson, J., … Sullivan, P. F. (2020). Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease. Nature Genetics, 52, 482-493. doi: 10.1038/s41588-020-0610-9
Osborne, A. J., Pearson, J. F., Noble, A. J., Gemmell, N. J., Horwood, L. J., Boden, J. M., … Kennedy, M. A. (2020). Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort. Translational Psychiatry, 10, 114. doi: 10.1038/s41398-020-0800-3
Pearson, A. G., Zawari, M., Pearson, J. F., & Hampton, M. B. (2020). Quantifying mitochondrial respiration in human lymphocytes and monocytes challenged with hydrogen peroxide. Free Radical Research, 54(4), 271-279. doi: 10.1080/10715762.2020.1753722
Dickerhof, N., Huang, J., Min, E., Michaëlsson, E., Lindstedt, E.-L., Pearson, J. F., Kettle, A. J., & Day, B. J. (2020). Myeloperoxidase inhibition decreases morbidity and oxidative stress in mice with cystic fibrosis-like lung inflammation. Free Radical Biology & Medicine, 152, 91-99. doi: 10.1016/j.freeradbiomed.2020.03.001
Slow, S., Pearson, J. F., Florkowski, C. M., Elder, P. A., Lewis, J. G., Kennedy, M. A., & Murdoch, D. R. (2020). Effect of genetic factors on the response to vitamin D3 supplementation in the VIDARIS randomised controlled trial. Nutrition, 75-76, 110761. doi: 10.1016/j.nut.2020.110761
Tranter-Entwistle, I., Mullaney, T. G., Noah, K., Pearson, J., Falvey, J., Gearry, R., & Eglinton, T. (2020). Long-term incidence of dysplasia and colorectal cancer in an ulcerative colitis population-based cohort. ANZ Journal of Surgery, 90, 821-825. doi: 10.1111/ans.15686
Richardson, A. K., Walker, L. C., Cox, B., Rollag, H., Robinson, B. A., Morrin, H., Pearson, J. F., … Currie, M. J. (2020). Breast cancer and cytomegalovirus. Clinical & Translational Oncology, 22, 585-602. doi: 10.1007/s12094-019-02164-1
Journal - Research Other
Wiggins, G. A. R., Walker, L. C., & Pearson, J. F. (2020). Genome-wide gene expression analyses of BRCA1- and BRCA2-associated breast and ovarian tumours. Cancers, 12(10), 3015. doi: 10.3390/cancers12103015
Conference Contribution - Published proceedings: Abstract
Lattimore, V., Parsons, M., Spurdle, A., Pearson, J., Northcott, H., Lehnert, K., … Morrin, H., Robinson, B., & Walker, L. (2020). Potential under-ascertainment of New Zealand women at high-risk of breast cancer in clinical care [Invited]. Proceedings of the Genetics Otago (GO) Zoom Symposium. Retrieved from https://blogs.otago.ac.nz/go/2020-3/
Wiggins, G., Pearson, J., Black, M., Dunbier, A., Merriman, T., & Walker, L. (2020). Variable expression quantitative trait loci analysis of breast cancer risk variants. New Zealand Medical Journal, 133(1524), (pp. 145). Retrieved from https://www.nzma.org.nz/journal
Noble, A., Pearson, J., Boden, J., Horwood, J., Kennedy, M., & Osborne, A. (2020). Understanding the interaction between maternal tobacco use during pregnancy and adult offspring with conduct disorder. New Zealand Medical Journal, 133(1524), (pp. 144). Retrieved from https://www.nzma.org.nz/journal
Working Paper; Discussion Paper; Technical Report
Fanning, N. C., Topless, R. K., Phipps-Green, A., Pearson, J. F., Cadzow, M., Major, T. J., … Merriman, T. R., & Stamp, L. K. (2020). Population-specific interaction of the TRIM46/MUC1 locus with cigarette smoking may influence the risk of gout. Research Square. doi: 10.21203/rs.3.rs-108669/v1
2019
Journal - Research Article
Thompson, G., & Pearson, J. F. (2019). No attributable effects of PRP on greater trochanteric pain syndrome. New Zealand Medical Journal, 132(1507), 22-32. Retrieved from https://www.nzma.org.nz/journal
Purcell, R. V., Schmeier, S., Lau, Y. C., Pearson, J. F., & Frizelle, F. A. (2019). Molecular subtyping improves prognostication of Stage 2 colorectal cancer. BMC Cancer, 19(1), 1155. doi: 10.1186/s12885-019-6327-4
Liau, Y., Cree, S. L., Maggo, S., Miller, A. L., Pearson, J. F., Gladding, P. A., & Kennedy, M. A. (2019). A multiplex pharmacogenetics assay using the MinION nanopore sequencing device. Pharmacogenetics & Genomics, 29(9), 207-215. doi: 10.1097/fpc.0000000000000385
Liau, Y., Maggo, S., Miller, A. L., Pearson, J. F., Kennedy, M. A., & Cree, S. L. (2019). Nanopore sequencing of the pharmacogene CYP2D6 allows simultaneous haplotyping and detection of duplications. Pharmacogenomics, 20(14), 1033-1047. doi: 10.2217/pgs-2019-0080
Keenan, J., Aitchison, A., Leaman, J., Pearson, J., & Frizelle, F. (2019). Faecal biomarkers do not always identify pre-cancerous lesions in patients who present in primary care with bowel symptoms. New Zealand Medical Journal, 132(1501), 48-56. Retrieved from https://www.nzma.org.nz/journal
Zhang, Q., Vallerga, C. L., Walker, R. M., Lin, T., Henders, A. K., Montgomery, G. W., … Kennedy, M., Pitcher, T., Pearson, J., … Anderson, T., … Visscher, P. M. (2019). Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing. Genome Medicine, 11(1), 54. doi: 10.1186/s13073-019-0667-1
Prickett, T. C. R., Spittlehouse, J. K., Miller, A. L., Liau, Y., Kennedy, M. A., Cameron, V. A., Pearson, J. F., Boden, J. M., Troughton, R. W., & Espiner, E. A. (2019). Contrasting signals of cardiovascular health among natriuretic peptides in subjects without heart disease. Scientific Reports, 9, 12108. doi: 10.1038/s41598-019-48553-y
Watson, H. J., Yilmaz, Z., Thornton, L. M., Hübel, C., Coleman, J. R. I., Gaspar, H. A., … Roberts, M., … Boden, J. M., … Horwood, L. J., … Pearson, J. F., … Jordan, J., Kennedy, M., … Bulik, C. M. (2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics, 51, 1207-1214. doi: 10.1038/s41588-019-0439-2
Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Attention Deficit/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of the PGC, Eating Disorder Working Group of the PGC, including Kennedy, M. A., Major Depressive Disorder Working Group of the PGC, Obsessive Compulsive Disorders and Tourette Syndrome Working Group of the PGC, Schizophrenia CLOZUK, Substance Use Disorder Working Group of the PGC, including Horwood, L. J., Pearson, J. F., … Polderman, T. J. C. (2019). Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls. Psychological Medicine, 49(7), 1166-1173. doi: 10.1017/S0033291718002039
Reynolds, R. H., Botía, J., Nalls, M. A., International Parkinson's Disease Genomics Consortium (IPDGC), including System Genomics of Parkinson's Disease (SGPD), Anderson, T., … Kennedy, M., Pearson, J., … Ryten, M. (2019). Moving beyond neurons: The role of cell type-specific gene regulation in Parkinson's disease heritability. npj Parkinson's Disease, 5, 6. doi: 10.1038/s41531-019-0076-6
Lopez-Perolio, I., Leman, R., Behar, R., Lattimore, V., Pearson, J. F., Castéra, L., … Walker, L. C., … de la Hoya, M. (2019). Alternative splicing and ACMG-AMP-2015-based classification of PALB2 genetic variants: An ENIGMA report. Journal of Medical Genetics, 56, 453-460. doi: 10.1136/jmedgenet-2018-105834
Morley-Bunker, A., Pearson, J., Currie, M. J., Morrin, H., Whitehead, M. R., Eglinton, T., & Walker, L. C. (2019). Assessment of intra-tumoural colorectal cancer prognostic biomarkers using RNA in situ hybridisation. Oncotarget, 10(14), 1425-1439. doi: 10.18632/oncotarget.26675
Lattimore, V. L., Pearson, J. F., Morley-Bunker, A. E., kConFab Investigators, Spurdle, A. B., Robinson, B. A., Currie, M. J., & Walker, L. C. (2019). Quantifying BRCA1 and BRCA2 mRNA isoform expression levels in single cells. International Journal of Molecular Sciences, 20(3), 693. doi: 10.3390/ijms20030693
Balasubramanian, D., Pearson, J. F., & Kennedy, M. A. (2019). Gene expression effects of lithium and valproic acid in a serotonergic cell line. Physiological Genomics, 51, 43-50. doi: 10.1152/physiolgenomics.00069.2018
Hock, B. D., Mulholland, K. S., Ganly, P., McKenzie, J. L., Pearson, J. F., & MacPherson, S. A. (2019). Impact of increased access to novel agents on the survival of multiple myeloma patients treated at a single New Zealand centre. Internal Medicine Journal, 49, 598-606. doi: 10.1111/imj.14155
Journal - Research Other
Keenan, J. I., Aitchison, A., Pearson, J. F., Frizelle, F. A., & Munday, J. S. (2019). Detection of the Bacteroides fragilis toxin gene in sheep with and without small intestinal adenocarcinoma. New Zealand Veterinary Journal, 67(6), 329-332. doi: 10.1080/00480169.2019.1651233
Conference Contribution - Published proceedings: Full paper
Venkatasubramanian, U., Pearson, J. F., Beckert, L., & Jones, R. D. (2019). Characteristic changes in the EEG signals between microsleeps and preceding responsive states. Proceedings of the 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS). (pp. 1709-1712). IEEE. doi: 10.1109/EMBC.2019.8857718
Conference Contribution - Published proceedings: Abstract
Osborne, A., Pearson, J., Noble, A., Gemmell, N., Horwood, J., Boden, J., Hore, T., … Kennedy, M. (2019). Genome-wide DNA methylation analysis in the Christchurch Health and Development Study reveals potential for epigenetic effects of cannabis use on pathways involved neurodevelopment and neuronal signalling. Proceedings of the 16th Asian Conference on Transcription. (pp. 55). Retrieved from https://act2019.p.events4you.currinda.com/days/2019-12-02
Doudney, K., Lacey, C. J., Bridgman, P. G., Mulder, R. T., Zarifeh, J. J., Kimber, B., Cadzow, M., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2019). Rare copy number variants involving cardiac function and development genes detected in earthquake induced takotsubo cardiomyopathy patients. European Journal of Human Genetics, 27(Suppl. 1), (pp. 160). doi: 10.1038/s41431-019-0407-4
Sinha, P., Cree, S., Balasubramanian, D., Pearson, J., & Kennedy, M. (2019). Gene expression effects of valproic acid in a serotonergic cell line. European Neuropsychopharmacology, 29(Suppl. 4), (pp. S1248-S1249). doi: 10.1016/j.euroneuro.2018.08.331
Osborne, A., Pearson, J., Gemmell, N., Boden, J., Horwood, J., & Kennedy, M. (2019). Methylome impacts of cannabis use in the Christchurch Health and Development Study. European Neuropsychopharmacology, 29(Suppl. 3), (pp. S851). doi: 10.1016/j.euroneuro.2017.08.125
Conference Contribution - Verbal presentation and other Conference outputs
Pearson, J., Osborne, A., Noble, A., Kennedy, M., Horwood, J., & Boden, J. (2019, August-September). Epigenetic impact of cannabis use in the Christchurch Health and Development Study. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Noble, A., Pearson, J., Boden, J., Horwood, J., Kennedy, M., & Osborne, A. (2019, August-September). Understanding the relationship between maternal tobacco smoking and offspring conduct disorder: Are metastable epialleles present? Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Working Paper; Discussion Paper; Technical Report
Munn-Chernoff, M. A., Johnson, E. C., Chou, Y.-L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., … Boden, J. M., … Horwood, L. J., … Pearson, J. F., … Jordan, J., Kennedy, M. A., … Agrawal, A. (2019). Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. bioRxiv. doi: 10.1101/741512
Osborne, A. J., Pearson, J. F., Noble, A. J., Gemmell, N. J., Horwood, L. J., Boden, J. M., … Kennedy, M. A. (2019). Genome-wide DNA methylation analysis of heavy cannabis exposure in a New Zealand longitudinal cohort. bioRxiv. Retrieved from https://www.biorxiv.org/content/10.1101/829598v2.supplementary-material
2018
Journal - Research Article
Newlands, S., Dickson, J., Pearson, J., Mansell, C., & Wilson, G. (2018). Neonatal conjunctivitis in the New Zealand Midland region. New Zealand Medical Journal, 131(1486), 9-17. Retrieved from https://www.nzma.org.nz/journal
Walters, R. K., Polimanti, R., Johnson, E. C., McClintick, J. N., Adams, M. J., Adkins, A. E., … Kennedy, M. A., … Pearson, J. F., … Agrawal, A. (2018). Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nature Neuroscience, 21(12), 1656-1669. doi: 10.1038/s41593-018-0275-1
Turner, R., Brennan, S. O., Ashby, L. V., Dickerhof, N., Hamzah, M. R., Pearson, J. F., Stamp, L. K., & Kettle, A. J. (2018). Conjugation of urate-derived electrophiles to proteins during normal metabolism and inflammation. Journal of Biological Chemistry, 293(51), 19886-19898. doi: 10.1074/jbc.RA118.005237
Thornton, L. M., Munn-Chernoff, M. A., Baker, J. H., Juréus, A., Parker, R., Henders, A. K., … Horwood, L. J., Boden, J. M., Pearson, J. F., … Jordan, J., Kennedy, M. A., … Bulik, C. M. (2018). The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods. Contemporary Clinical Trials, 74, 61-69. doi: 10.1016/j.cct.2018.09.015
Slow, S., Epton, M., Storer, M., Thiessen, R., Lim, S., Wong, J., Chin, P., Tovaranonte, P., Pearson, J., Chambers, S. T., Murdoch, D. R., and VIDCAPS Group, including Jardine, D., & Pithie, A. (2018). Effect of adjunctive single high-dose vitamin D3 on outcome of community-acquired pneumonia in hospitalised adults: The VIDCAPS randomised controlled trial. Scientific Reports, 8(1), 13829. doi: 10.1038/s41598-018-32162-2
Stevens, A. J., Rucklidge, J. J., Darling, K. A., Eggleston, M. J. F., Pearson, J. F., & Kennedy, M. A. (2018). Methylomic changes in response to micronutrient supplementation and MTHFR genotype. Epigenomics, 10(9), 1201-1214. doi: 10.2217/epi-2018-0029
Purcell, R. V., Kaakoush, N. O., Mitchell, H. M., Pearson, J. F., & Keenan, J. I. (2018). Gastrointestinal pathobionts in pediatric Crohn's disease patients. International Journal of Microbiology, 2018, 9203908. doi: 10.1155/2018/9203908
Pitcher, T. L., Myall, D. J., Pearson, J. F., Lacey, C. J., Dalrymple-Alford, J. C., Anderson, T. J., & MacAskill, M. R. (2018). Parkinson's disease across ethnicities: A nationwide study in New Zealand. Movement Disorders, 33(9), 1440-1448. doi: 10.1002/mds.27389
Lacey, C. J., Doudney, K., Bridgman, P. G., George, P. M., Mulder, R. T., Zarifeh, J. J., Kimber, B., Cadzow, M. J., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2018). Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. Scientific Reports, 8, 7548. doi: 10.1038/s41598-018-25827-5
Lattimore, V. L., Pearson, J. F., Currie, M. J., Spurdle, A. B., kConFab Investigators, Robinson, B. A., & Walker, L. C. (2018). Investigation of experimental factors that underlie BRCA1/2 mRNA isoform expression variation: Recommendations for utilising targeted RNA sequencing to evaluate potential spliceogenic variants. Frontiers in Oncology, 8, 140. doi: 10.3389/fonc.2018.00140
Conference Contribution - Published proceedings: Abstract
Fanning, N., Merriman, T. R., Phipps-Green, A., Pearson, J., Topless, R., Cadzow, M., … Dalbeth, N., & Stamp, L. K. (2018). An ancestral-specific interaction of TRIM46 with a past-history of smoking may influence gout risk. Arthritis & Rheumatology, 70(9, Suppl.), 2231. doi: 10.1002/art.40700
Morley-Bunker, A., Pearson, J., Currie, M., Morrin, H., Whitehead, M., Eglinton, T., & Walker, L. (2018). Intratumoural assessment of candidate colorectal cancer prognostic markers using RNA in situ hybridization. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/
Wiggins, G., Pearson, J., Black, M., Dunbier, A., & Walker, L. (2018). Expression variability is associated with breast tumour subtype. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/
Conference Contribution - Poster Presentation (not in published proceedings)
Wiggins, G., Pearson, J., Black, M., Dunbier, A., & Walker, L. (2018, August). Expression variability is associated with breast tumour subtype. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Myall, D., Anderson, T., Pearson, J., Dalrymple-Alford, J., MacAskill, M., & Pitcher, T. (2018, November). Do commonly used drugs reduce the risk of Parkinson's. Verbal presentation at the 4th Pharmacoepidemiology Research Network Symposium, Dunedin, New Zealand.
Sinha, P., Cree, S., Miller, A. L., Pearson, J. F., & Kennedy, M. A. (2018, August). Gene expression effects of sodium valproate in a serotonergic cell line. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2017
Journal - Research Article
Maggo, S. D. S., Chua, E. W., Chin, P., Cree, S., Pearson, J., Doogue, M., & Kennedy, M. A. (2017). A New Zealand platform to enable genetic investigation of adverse drug reactions. New Zealand Medical Journal, 130(1466), 62-69. Retrieved from http://www.nzma.org.nz/journal
Dickerhof, N., Pearson, J. F., Hoskin, T. S., Berry, L. J., Turner, R., Sly, P. D., Kettle, A. J., on behalf of AREST CF. (2017). Oxidative stress in early cystic fibrosis lung disease is exacerbated by airway glutathione deficiency. Free Radical Biology & Medicine, 113, 236-243. doi: 10.1016/j.freeradbiomed.2017.09.028
Pearson, J. F., Pullar, J. M., Wilson, R., Spittlehouse, J. K., Vissers, M. C. M., Skidmore, P. M. L., Willis, J., Cameron, V. A., & Carr, A. C. (2017). Vitamin C status correlates with markers of metabolic and cognitive health in 50-year-olds: Findings of the CHALICE Cohort Study. Nutrients, 9(8), 831. doi: 10.3390/nu9080831
Myall, D. J., Pitcher, T. L., Pearson, J. F., Dalrymple-Alford, J. C., Anderson, T. J., & MacAskill, M. R. (2017). Parkinson's in the oldest old: Impact on estimates of future disease burden. Parkinsonism & Related Disorders, 42, 78-84. doi: 10.1016/j.parkreldis.2017.06.018
Grant, E., Gearry, R. B., Wilson, R., Pearson, J., & Skidmore, P. M. L. (2017). Home availability of fruit and vegetables and obesogenic foods as an indicator of nutrient intake in 50 year olds from Canterbury, New Zealand. Asia Pacific Journal of Clinical Nutrition, 26(3), 524-530. doi: 10.6133/apjcn.042016.11
Gandhi, J., Davidson, C., Hall, C., Pearson, J., Eglinton, T., Wakeman, C., & Frizelle, F. (2017). Population-based study demonstrating an increase in colorectal cancer in young patients. British Journal of Surgery, 104(8), 1063-1068. doi: 10.1002/bjs.10518
Walker, L. C., Pearson, J. F., Wiggins, G. A. R., Giles, G. G., Hopper, J. L., & Southey, M. C. (2017). Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry. Breast Cancer Research, 19, 30. doi: 10.1186/s13058-017-0825-6
Walker, L. C., Marquart, L., Pearson, J. F., Wiggins, G. A. R., O'Mara, T. A., Parsons, M. T., … Spurdle, A. B. (2017). Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. European Journal of Human Genetics, 25, 432-438. doi: 10.1038/ejhg.2016.203
Purcell, R. V., Pearson, J., Aitchison, A., Dixon, L., Frizelle, F. A., & Keenan, J. I. (2017). Colonization with enterotoxigenic Bacteroides fragilis is associated with early-stage colorectal neoplasia. PLoS ONE, 12(2), e0171602. doi: 10.1371/journal.pone.0171602
Pearson, J. F., Alla, S., Clarke, G., Mason, D. F., Anderson, T., Richardson, A., Miller, D. H., … Abernethy, D. A., … Taylor, B. V. (2017). Multiple sclerosis impact on employment and income in New Zealand. Acta Neurologica Scandinavica, 136(3), 223-232. doi: 10.1111/ane.12714
Appleby, S., Pearson, J. F., Aitchison, A., Spittlehouse, J. K., Joyce, P. R., & Kennedy, M. A. (2017). Mean telomere length is not associated with current health status in a 50-year-old population sample. American Journal of Human Biology, 29(1), e22906. doi: 10.1002/ajhb.22906
Conference Contribution - Published proceedings: Abstract
Gandhi, J., Frizelle, F., Pearson, J., Eglinton, T., Wakeman, C., & Davidson, C. (2017). Population based study demonstrating an increase in colorectal cancer in young patients. ANZ Journal of Surgery, 87(Suppl. 1), (pp. 28-29). doi: 10.1111/ans.13990
Osborne, A., Pearson, J., Hore, T., Horwood, J., Macartney-Coxson, D., Gemmell, N., & Kennedy, M. (2017). Identifying methylome changes in response to heavy, long-term cannabis use, in a large longitudinal cohort. Proceedings of the Annual Conference of the Genetics Society of Australasia (GSA) with the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB). 519. Retrieved from http://gen2017.w.events4you.currinda.com
Cree, S., Maggo, S., Slow, S., Ton, K., de Jong, L., Anderson, T., Pearson, J., Miller, A., Walker, L., Murdoch, D., & Kennedy, M. (2017). Long read nanopore sequencing in the laboratory. Proceedings of the MapNet Conference. Retrieved from http://scienceevents.co.nz/mapnet/
Pearson, J. F., Wiggins, G. A. R., Black, M., Dunbier, A., & Walker, L. C. (2017). Expression variability is associated with breast cancer tumour subtype. Proceedings of the American Society of Human Genetics (ASHG) Annual Meeting. 746. Retrieved from http://www.ashg.org/2017meeting/
Conference Contribution - Verbal presentation and other Conference outputs
Dickerhof, N., Pearson, J. F., Hoskin, T. S., Sly, P. D., & Kettle, A. J. (2017, August). Myeloperoxidase is associated with bronchiectasis in children with cystic fibrosis. Verbal presentation at the 10th International Human Peroxidase Meeting, Breckenridge, USA.
Kennedy, M. A., Cree, S. L., Miller, A. L., Pearson, J., Maggo, S., Liau, Y., Ton, K., de Jong, L., & Walker, L. C. (2017, September). The MinION nanopore sequencer: Toy or tool? Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Liau, Y., Cree, S. M., Maggo, S., Miller, A. L., Pearson, J., & Kennedy, M. A. (2017, September). A nanopore sequencing-based multiplex assay for pharmacogenetics of clopidogrel and warfarin. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Osborne, A. J., Pearson, J. F., Horwood, J., Hore, T., Macartney-Coxson, D., Gemmell, N. J., & Kennedy, M. A. (2017, September). Cannabis use and epigenetics: EPIC insights into the human methylome. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Working Paper; Discussion Paper; Technical Report
Lacey, C. J., Doudney, K., Bridgman, P. G., George, P. M., Mulder, R. T., Zarifeh, J. A., Kimber, B., Cadzow, M. J., Black, M. A., Merriman, T. R., … Pearson, J. F., Cameron, V. A., & Kennedy, M. A. (2017). Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy. bioRxiv. doi: 10.1101/144675
2016
Journal - Research Article
Spittlehouse, J. K., Vierck, E., Pearson, J. F., & Joyce, P. R. (2016). Personality, mental health and demographic correlates of hoarding behaviours in a midlife sample. PeerJ, 4, e2826. doi: 10.7717/peerj.2826
Purcell, R. V., Pearson, J., Frizelle, F. A., & Keenan, J. I. (2016). Comparison of standard, quantitative and digital PCR in the detection of enterotoxigenic Bacteroides fragilis. Scientific Reports, 6, 34554. doi: 10.1038/srep34554
Hock, B. D., McIntosh, N. D., McKenzie, J. L., Pearson, J. F., Simcock, J. W., & MacPherson, S. A. (2016). Incidence of cutaneous squamous cell carcinoma in a New Zealand population of chronic lymphocytic leukaemia patients. Internal Medicine Journal, 46(12), 1414-1421. doi: 10.1111/imj.13261
Keenan, J. I., Aitchison, A., Purcell, R. V., Greenlees, R., Pearson, J. F., & Frizelle, F. A. (2016). Screening for enterotoxigenic Bacteroides fragilis in stool samples. Anaerobe, 40, 50-53. doi: 10.1016/j.anaerobe.2016.05.004
Seddon, A., Hock, B., Miller, A., Frei, L., Pearson, J., McKenzie, J., Simcock, J., & Currie, M. (2016). Cutaneous squamous cell carcinomas with markers of increased metastatic risk are associated with elevated numbers of neutrophils and/or granulocytic myeloid derived suppressor cells. Journal of Dermatological Science, 83(2), 124-130. doi: 10.1016/j.jdermsci.2016.04.013
Morley-Bunker, A., Walker, L. C., Currie, M. J., Pearson, J., & Eglinton, T. (2016). Translating colorectal cancer genetics into clinically useful biomarkers. Colorectal Disease, 18(8), 749-762. doi: 10.1111/codi.13334
Alla, S., Pearson, J. F., Taylor, B. V., Miller, D. H., Clarke, G., Richardson, A., … Abernethy, D. A., … Mason, D. F. (2016). Disability profile of multiple sclerosis in New Zealand. Journal of Clinical Neuroscience, 28, 97-101. doi: 10.1016/j.jocn.2015.09.020
Goh, T., Bird, P., Pearson, J., & Mustard, J. (2016). Educational, employment, and social participation of young adult graduates from the Southern Cochlear Implant Programme, New Zealand. Cochlear Implants International, 17(1), 31-51. doi: 10.1179/1754762815Y.0000000018
Journal - Research Other
Alla, S., Pearson, J. F., Taylor, B. V., Roxburgh, R., Clarke, G., Miller, D. H., Richardson, A., Abernethy, D. A., … Mason, D. F. (2016). An investigation of the relationship between latitude and multiple sclerosis severity in New Zealand. Multiple Sclerosis Journal, 22(5), 705-707. doi: 10.1177/1352458515605909
Conference Contribution - Published proceedings: Abstract
Myall, D. J., Pitcher, T. L., MacAskill, M. R., Pearson, J. F., Lacey, C., Dalrymple-Alford, J. C., & Anderson, T. J. (2016). Epidemiology of Parkinson’s in New Zealand: Sex, age, and future burden. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 70). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Pitcher, T. L., Myall, D. J., MacAskill, M. R., Pearson, J. F., Lacey, C., Dalrymple-Alford, J. C., & Anderson, T. J. (2016). Ethnic and regional differences in Parkinson’s disease in New Zealand. In B. Leitch (Ed.), Proceedings of the 34th International Australasian Winter Conference on Brain Research. (pp. 31). AWCBR. Retrieved from http://www.otago.ac.nz/awcbr
Pitcher, T. L., Myall, D. J., MacAskill, M. R., Pearson, J. F., Lacey, C. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2016). Ethnic differences in rates of Parkinson's in New Zealand: A nation-wide prevalence and incidence study. Movement Disorders, 31(Suppl. 2), (pp. S147-S148). doi: 10.1002/mds.26688
Myall, D. J., Pitcher, T. L., MacAskill, M. R., Pearson, J. F., Lacey, C. J., Dalrymple-Alford, J. C., & Anderson, T. J. (2016). Parkinson's in an aging population: Implications from a nation-wide prevalence and incidence study in New Zealand. Movement Disorders, 31(Suppl. 2), (pp. S145). doi: 10.1002/mds.26688
Conference Contribution - Verbal presentation and other Conference outputs
Purcell, R., Pearson, J., Visnovska, M., Schmeier, S., & Frizelle, F. (2016, November). Consensus molecular classification of colorectal cancer and association with the colonic microbiome. Verbal presentation at the Joint Meeting of the New Zealand Microbiological Society (NZMS) and the New Zealand Society for Biochemistry and Molecular Biology (NZSBMB), Christchurch, New Zealand.
Wiggins, G. A. R., Pearson, J., Dunbier, A., Black, M., & Walker, L. (2016, August-September). Gene expression variability in breast tumours. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
Purcell, R., Pearson, J., Keenan, J., Schmeier, S., & Frizelle, F. (2016, August-September). Bacterial dysbiosis and the development of colorectal cancer. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Nelson, New Zealand.
2015
Journal - Research Article
Walker, L. C., Wiggins, G. A. R., & Pearson, J. F. (2015). The role of constitutional copy number variants in breast cancer. Microarrays, 4(3), 407-423. doi: 10.3390/microarrays4030407
Osborne, A. J., Pearson, J., Chilvers, B. L., Kennedy, M. A., & Gemmell, N. J. (2015). Examining the role of components of Slc11a1 (Nramp1) in the susceptibility of New Zealand sea lions (Phocarctos hookeri) to disease. PLoS ONE, 10(4), e0122703. doi: 10.1371/journal.pone.0122703
Osborne, A. J., Pearson, J., Negro, S. S., Chilvers, B. L., Kennedy, M. A., & Gemmell, N. J. (2015). Heterozygote advantage at MHC DRB may influence response to infectious disease epizootics. Molecular Ecology, 24, 1419-1432. doi: 10.1111/mec.13128
Gerring, Z., Pearson, J. F., Morrin, H. R., Robinson, B. A., Harris, G. C., & Walker, L. C. (2015). Phosphohistone H3 outperforms Ki67 as a marker of outcome for breast cancer patients. Histopathology, 67(4), 538-547. doi: 10.1111/his.12678
Richardson, A. K., Currie, M. J., Robinson, B. A., Morrin, H., Phung, Y., Pearson, J. F., … Walker, L. C. (2015). Cytomegalovirus and Epstein-Barr Virus in breast cancer. PLoS ONE, 10(2), e0118989. doi: 10.1371/journal.pone.0118989
Jodczyk, S., Pearson, J. F., Aitchison, A., Miller, A. L., Hampton, M. B., & Kennedy, M. A. (2015). Telomere length measurement on the Roche LightCycler 480 platform. Genetic Testing & Molecular Biomarkers, 19(2), 63-68. doi: 10.1089/gtmb.2014.0208
Moir-Meyer, G. L., Pearson, J. F., Lose, F., The Australian National Endometrial Cancer Study Group, Scott, R. J., McEvoy, M., … Walker, L. C. (2015). Rare germline copy number deletions of likely functional importance are implicated in endometrial cancer predisposition. Human Genetics, 134(3), 269-278. doi: 10.1007/s00439-014-1507-4
Conference Contribution - Published proceedings: Abstract
Wheeler, N. E., Cameron, V. A., Pearson, J. F., Gardener, P. T., Moravec, C. S., Sweet, W. E., … Troughton, R. W., Richards, A. M., & Pilbrow, A. P. (2015). Expression quantitative trait locus (eQTL) map for genetic variants associated with cardiovascular traits in human heart. Circulation, 132, A17027. [Abstract]
Alla, S., Taylor, B. V., Pearson, J. F., Richardson, A., Miller, D. H., Clarke, G., Abernethy, D., … Mason, D. F. (2015). Characteristics of familial multiple sclerosis in New Zealand: A country-wide population based study. Multiple Sclerosis Journal, 23(11, Suppl.), (pp. 722). doi: 10.1177/1352458515602639
Alla, S., Pearson, J. F., Taylor, B. V., Miller, D. H., Richardson, A., Clarke, G., Abernethy, D., … Mason, D. F. (2015). Age has an effect on disability independent of age at onset of symptoms and disease duration. Multiple Sclerosis Journal, 23(11, Suppl.), (pp. 397-398). doi: 10.1177/1352458515602642
Alla, S., Pearson, J. F., Clarke, G., Mason, D. F., Miller, D. H., Richardson, A., Anderson, T., Abernethy, D., … Taylor, B. V. (2015). Employment among persons with multiple sclerosis in New Zealand. Multiple Sclerosis Journal, 23(11, Suppl.), (pp. 419). doi: 10.1177/1352458515602642
Seddon, A. R., Hock, B. D., Miller, A. P., Frei, L. P., Pearson, J. F., McKenzie, J. L., Simcock, J. W., & Currie, M. J. (2015). Neutrophils in cutaneous squamous cell carcinoma: Potential prognostic markers? New Zealand Medical Journal, 128(1421). Retrieved from https://www.nzma.org.nz/journal
Lattimore, V., Pearson, J., Currie, M., Robinson, B., & Walker, L. (2015). Evaluating BRCA1 and BRCA2 sequence variants that modulate isoform expression. New Zealand Medical Journal, 128(1421). Retrieved from https://www.nzma.org.nz/journal
Conference Contribution - Poster Presentation (not in published proceedings)
Sinha, P., Balasubramanain, D., Pearson, J. F., & Kennedy, M. A. (2015, August-September). RNA-Seq analysis of gene expression changes caused by mood stabilizer drugs in a serotonergic cell line. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Lattimore, V., Pearson, J. F., Currie, M., Robinson, B. A., Spurdle, A. B., & Walker, L. C. (2015, August-September). Using splicing assays to interpret variants of unknown clinical significance in BRCA1 and BRCA2. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Wheeler, N. E., Cameron, V. A., Pearson, J. F., Gardner, P. P., Moravec, C. S., Sweet, W. E., … Troughton, R. W., Richards, A. M., & Pilbrow, A. P. (2015, August-September). An expression quantitative trait locus (eQTL) map for human heart. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Pearson, J. F., & Cameron, V. A. (2015, August-September). DNA methylation in patients with a strong family history of early onset coronary heart disease. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2014
Journal - Research Article
Wilson, R., Gearry, R. B., Grant, E., Pearson, J., & Skidmore, P. M. L. (2014). Home food availability is associated with multiple socio-economic indicators in 50 year olds from Canterbury, New Zealand. Asia Pacific Journal of Clinical Nutrition, 23(4), 714-722. doi: 10.6133/apjcn.2014.23.4.04
Spencer, R., Gearry, R., Pearson, J., & Skidmore, P. (2014). Relationship between fructose and lactose intakes and functional gastrointestinal symptoms in a sample of 50-year-old Cantabrians in New Zealand. New Zealand Medical Journal, 127(1406). Retrieved from http://www.nzma.org.nz/journal
Thorpe, A. M., Pearson, J. F., Schluter, P. J., Spittlehouse, J. K., & Joyce, P. R. (2014). Attitudes to aging in midlife are related to health conditions and mood. International Psychogeriatrics, 26(12), 2061-2071. doi: 10.1017/s1041610214001550
Spittlehouse, J. K., Vierck, E., Pearson, J. F., & Joyce, P. R. (2014). Temperament and character as determinants of well-being. Comprehensive Psychiatry, 55(7), 1679-1687. doi: 10.1016/j.comppsych.2014.06.011
Wall, C. L., Gearry, R. B., Pearson, J., Parnell, W., & Skidmore, P. M. L. (2014). Dietary intake in midlife and associations with standard of living, education and nutrition literacy. New Zealand Medical Journal, 127(1397). Retrieved from http://www.nzma.org.nz/journal
Pearson, J. F., Alla, S., Clarke, G., Taylor, B. V., Miller, D. H., Richardson, A., & Mason, D. F. (2014). Multiple sclerosis in New Zealand Māori. Multiple Sclerosis Journal, 20(14), 1892-1895. doi: 10.1177/1352458514535130
Jodczyk, S., Fergusson, D. M., Horwood, L. J., Pearson, J. F., & Kennedy, M. A. (2014). No association between mean telomere length and life stress observed in a 30 year birth cohort. PLoS ONE, 9(5), e97102. doi: 10.1371/journal.pone.0097102
Spittlehouse, J. K., Joyce, P. R., Vierck, E., Schluter, P. J., & Pearson, J. F. (2014). Ongoing adverse mental health impact of the earthquake sequence in Christchurch, New Zealand. Australian & New Zealand Journal of Psychiatry, 48(8), 756-763. doi: 10.1177/0004867414527522
Alla, S., Pearson, J., Debernard, L., Miller, D., & Mason, D. (2014). The increasing prevalence of multiple sclerosis in New Zealand. Neuroepidemiology, 42, 154-160. doi: 10.1159/000358174
Kuiper, C., Dachs, G. U., Munn, D., Currie, M. J., Robinson, B. A., Pearson, J. F., & Vissers, M. C. M. (2014). Increased tumour ascorbate is associated with extended disease-free survival and decreased hypoxia-inducible factor-1 activation in human colorectal cancer. Frontiers in Oncology, 4, 10. doi: 10.3389/fonc.2014.00010
Conference Contribution - Published proceedings: Abstract
Jodczyk, S., Pearson, J. F., Fergusson, D. M., Horwood, L. J., Spittlehouse, J. K., Joyce, P. R., Hampton, M. B., & Kennedy, M. A. (2014). No association between telomere length and exposure to life course stress or adversity in two longitudinal New Zealand cohorts. Proceedings of the American Society of Human Genetics (ASHG) Annual Meeting. 1325M. Retrieved from http://www.ashg.org/
Nolan, A., Roberts, R. L., Wallace, M. C., Pearson, J., van Rij, A., Jones, G. T., Jackson, P. M., Schultz, M. P., Day, A. S., & Gearry, R. B. (2014). Genetic association of oral Crohn disease with intestinal Crohn disease. Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology, 117(5), (pp. e347). doi: 10.1016/j.oooo.2014.01.072
Alla, S., Pearson, J., Richardson, A., & Mason, D. (2014). The incidence of multiple sclerosis in New Zealand, 2013: A population-based study. Multiple Sclerosis Journal, 20(Suppl. 1), (pp. 67-284). doi: 10.1177/1352458514546077
Jodczyk, S., Pearson, J. F., Fergusson, D. M., Horwood, L. J., Spittlehouse, J. K., Joyce, P. R., Hampton, M. B., & Kennedy, M. A. (2014). Association between telomere length and life stress in two New Zealand cohorts. New Zealand Medical Journal, 127(1396). Retrieved from http://www.nzma.org.nz/journal
Kuiper, C., Dachs, G., Currie, M., Pearson, J., Munn, D., & Vissers, M. (2014). Tumor ascorbate content is associated with extended disease-free survival and decreased hypoxia-inducible factor-1 activation in patients with colorectal cancer. Proceedings of the American Association for Cancer Research (AACR) 105th Annual Meeting. Retrieved from http://www.aacr.org/home/scientists/meetings--workshops/aacr-annual-meeting-2014.aspx
Conference Contribution - Poster Presentation (not in published proceedings)
Spittlehouse, J., Vierck, E., Pearson, J., & Joyce, P. (2014, July). Temperament and character as determinants of well-being. Poster session presented at the European Association of Personality Psychology (EAPP) 17th European Conference on Personality: Putting Personality in Context, Lausanne, Switzerland.
Jodczyk, S., Pearson, J., Fergusson, D., Horwood, J., Spittlehouse, J., Joyce, P., Hampton, M., & Kennedy, M. (2014, September). No association between telomere length and exposure to life course stress in two longitudinal New Zealand cohorts. Poster session presented at the Division of Health Sciences Research Forum: Learning Different Research Languages, Dunedin, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Keenan, J., Aitchison, A., Greenlees, R., Pearson, J., & Frizelle, F. (2014, October). Are toxin-producing strains of Bacteroides fragilis involved in colorectal cancer? Verbal presentation at the New Zealand Society for Oncology (NZSO) Conference, Tauranga, New Zealand.
2013
Journal - Research Article
Sanders, A. D., Stevenson, C., Pearson, J., Burt, M., McGeoch, G., Hudson, B., & Eglinton, T. W. (2013). A novel pathway for investigation of colorectal symptoms with colonoscopy or computed tomography colonography. New Zealand Medical Journal, 126(1382). Retrieved from http://www.nzma.org.nz/journal
Schluter, P. J., Spittlehouse, J. K., Cameron, V. A., Chambers, S., Gearry, R., Jamieson, H. A., Kennedy, M., Lacey, C. J., Murdoch, D. R., Pearson, J., Porter, R. J., Richards, M., Skidmore, P. M. L., Troughton, R., Vierck, E., & Joyce, P. R. (2013). Canterbury Health, Ageing and Life Course (CHALICE) study: Rationale, design and methodology. New Zealand Medical Journal, 126(1375). Retrieved from http://www.nzma.org.nz/journal
Maze, M. J., Skea, S., Pithie, A., Metcalf, S., Pearson, J. F., & Chambers, S. T. (2013). Prevalence of concurrent deep vein thrombosis in patients with lower limb cellulitis: A prospective cohort study. BMC Infectious Diseases, 13, 141. doi: 10.1186/1471-2334-13-141
Taylor, B. V., Palmer, A., Simpson, Jr, S., Lucas, R., NZMSPS Study Group, Simmons, R. D., Mason, D., Pearson, J., Clarke, G., … Richardson, A., & Abernethy, D. (2013). Assessing possible selection bias in a national voluntary MS longitudinal study in Australia. Multiple Sclerosis Journal, 19(12), 1627-1631. doi: 10.1177/1352458513481511
Keenan, J. I., Salm, N., Pearson, J. F., Gearry, R. B., & Day, A. S. (2013). Campylobacter seroreactivity in adults with recent onset of Crohn’s disease. Journal of Gastroenterology & Hepatology Research, 2(3), 468-472. doi: 10.6051/j.issn.2224-3992.2013.02.228
Fernyhough, L. J., Hock, B. D., Taylor, J., Pearson, J., & Ganly, P. (2013). Survival of myeloma patients following the introduction of thalidomide as a second-line therapy: A retrospective study at a single New Zealand centre. Internal Medicine Journal, 43(2), 130-137. doi: 10.1111/j.1445-5994.2012.02819.x
Journal - Research Other
Pearson, J. F., Fergusson, D. M., Horwood, L. J., Miller, A. L., Sullivan, P. F., Youfang, L. E., & Kennedy, M. A. (2013). Increased risk of major depression by childhood abuse is not modified by CNR1 genotype. American Journal of Medical Genetics Part B, 162(2), 224-226. doi: 10.1002/ajmg.b.32124
Conference Contribution - Published proceedings: Abstract
Skidmore, P. M. L., Grant, E., Gearry, R. B., Wilson, R., & Pearson, J. (2013). Home availability of fruit and vegetables and obesogenic foods as an indicator of nutrient intake in 50 year olds from Canterbury, New Zealand. Australasian Medical Journal, 6(11), (pp. 673). [Abstract]
Alla, S., Pearson, J., & Mason, D. (2013). The increasing prevalence of multiple sclerosis in New Zealand. Multiple Sclerosis Journal, 19(11, Suppl. 1), (pp. 345). doi: 10.1177/1352458513502429
Alla, S., Roxburgh, R., Pearson, J., Taylor, B., & Mason, D. (2013). Latitude is not associated with multiple sclerosis disability in New Zealand. Multiple Sclerosis Journal, 19(11, Suppl. 1), (pp. 46). doi: 10.1177/1352458513502433
Lines, J., Khashram, M., Pearson, J., & Roake, J. (2013). Do operating starting times of ruptured AAA repair influence mortality? Proceedings of the Australia and New Zealand Society of Vascular Surgery (ANZSVS) Vascular Conference: Evidence Based Vascular Surgery and Organisation of Vascular Surgery Services. (pp. 48). Retrieved from http://www.vascularconference.com/2013/program/
Moir-Meyer, G. L., Lose, F., Pearson, J. F., Tan, Y., The Australian National Endometrial Cancer Study Group, Studies of Epidemiology and Risk Factors in Cancer Heredity, … Walker, L. C. (2013). Identification of rare DNA copy number variants overlapping mismach repair pathway genes in endometrial cancer patients and their potential contribution to disease risk. New Zealand Medical Journal, 126(1375). Retrieved from http://www.nzma.org.nz/journal
Ali, I., Davidson, P., Yamit, M., & Pearson, J. (2013). The Christchurch Radical Cystectomy Database: A critical prospective audit 2007-2012. BJU International, 111(Suppl. 1), (pp. 73-74). doi: 10.1111/bju.12069
Conference Contribution - Poster Presentation (not in published proceedings)
Kuiper, C., Dachs, G. U., Munn, D., Currie, M. J., Robinson, B. A., Pearson, J. F., & Vissers, M. C. M. (2013, August). Increased tumour ascorbate is associated with extended disease-free survival and decreased hypoxia-inducible factor-1 activation in patients with colorectal cancer. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2012
Journal - Research Article
Brett, C. N., Barnett, S. G., & Pearson, J. (2012). Postoperative plasma paracetamol levels following oral or intravenous paracetamol administration: A double-blind randomised controlled trial. Anaesthesia & Intensive Care, 40(1), 166-171.
Pilbrow, A. P., Folkersen, L., Pearson, J. F., Brown, C. M., McNoe, L., Wang, N. M., … Black, M. A., Troughton, R. W., Richards, A. M., … Cameron, V. A. (2012). The chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues. PLoS ONE, 7(6), e39574. doi: 10.1371/journal.pone.0039574
Richardson, A. K., Clarke, G., Sabel, C. E., Pearson, J. F., Mason, D. F., & Taylor, B. V. (2012). Method for identifying eligible individuals for a prevalence survey in the absence of a disease register or population register. Internal Medicine Journal, 42(11), 1207-1212. doi: 10.1111/j.1445-5994.2012.02754.x
Eglinton, T. W., Roberts, R., Pearson, J., Barclay, M., Merriman, T. R., Frizelle, F. A., & Gearry, R. B. (2012). Clinical and genetic risk factors for perianal Crohn's disease in a population-based cohort. American Journal of Gastroenterology, 107, 589-596. doi: 10.1038/ajg.2011.437
Conference Contribution - Published proceedings: Abstract
Alla, S., Pearson, J., Clarke, G., Taylor, B., & Mason, D. (2012). The clinical characteristics of multiple sclerosis in Maori are homogeneous with that of the national cohort. Multiple Sclerosis Journal, 18(Suppl. 4), (pp. 324). doi: 10.1177/1352458512459021
Alla, S., Pearson, J., Clarke, G., Taylor, B., & Mason, D. (2012). The low prevalence of multiple sclerosis in Maori is not responsible for the latitude gradient in New Zealand. Multiple Sclerosis Journal, 18(Suppl. 4), (pp. 88). doi: 10.1177/1352458512459019
Thorpe, A., Joyce, P., Pearson, J., & Schluter, P. (2012). Attitudes to ageing in midlife. Proceedings of the International Federation on Ageing (IFA) 11th Global Conference: Ageing Connects. Retrieved from http://www.ifa2012.com/abstracts/list-of-abstracts
Conference Contribution - Poster Presentation (not in published proceedings)
Moir-Meyer, G., Lose, F., Pearson, J. F., Tan, Y., The Australian National Endometrial Cancer Study Group, The Hunter Community Study, … Walker, L. C. (2012, September). Identification of rare DNA copy number variants overlapping mismatch repair pathway genes in endometrial cancer patients and their potential contribution to disease risk. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand.
2011
Journal - Research Article
Bhandari, S., Chambers, S., Pearson, J., Syhre, M., Epton, M., & Scott-Thomas, A. (2011). Determining the limits and confounders for the 2-pentyl furan breath test by gas chromatography/mass spectrometry. Journal of Chromatography B, 879(26), 2815-2820. doi: 10.1016/j.jchromb.2011.08.010
Hudson, B., Toop, L., Mangin, D., & Pearson, J. (2011). Risk communication methods in hip fracture prevention: A randomised trial in primary care. British Journal of General Practice, 61(589), e469-e476. doi: 10.3399/bjgp11X588439
Glubb, D. M., Gearry, R. B., Barclay, M. L., Roberts, R. L., Pearson, J., Keenan, J. I., McKenzie, J., & Bentley, R. W. (2011). NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease. World Journal of Gastroenterology, 17(23), 2829-2837. doi: 10.3748/wjg.v17.i23.2829
Scott-Thomas, A., Pearson, J., & Chambers, S. (2011). Potential sources of 2-aminoacetophenone to confound the Pseudomonas aeruginosa breath test, including analysis of a food challenge study. Journal of Breath Research, 5(4), 046002. doi: 10.1088/1752-7155/5/4/046002
Heppenstall, C. P., Wilkinson, T. J., Hanger, H. C., Keeling, S., & Pearson, J. (2011). Factors related to care home admission in the year following hospitalisation in frail older adults. Age & Ageing, 40(4), 513-516. doi: 10.1093/ageing/afr045
Melzer, T. R., Watts, R., MacAskill, M. R., Pearson, J. F., Rüeger, S., Pitcher, T. L., Livingston, L., Graham, C., Keenan, R., … Dalrymple-Alford, J. C., & Anderson, T. J. (2011). Arterial spin labelling reveals an abnormal cerebral perfusion pattern in Parkinson's disease. Brain, 134(3), 845-855. doi: 10.1093/brain/awq377
Vissers, M. C. M., Bozonet, S. M., Pearson, J. F., & Braithwaite, L. J. (2011). Dietary ascorbate intake affects steady state tissue concentrations in vitamin C-deficient mice: Tissue deficiency after suboptimal intake and superior bioavailability from a food source (kiwifruit). American Journal of Clinical Nutrition, 93, 292-301. doi: 10.3945/ajcn.110.004853
Conference Contribution - Published proceedings: Abstract
Pilbrow, A. P., Pearson, J. F., McNoe, L., Ellis, K. L., Black, M. A., Sweet, W. E., … Troughton, R. W., Richards, A. M., … Cameron, V. A. (2011). Chromosome 1q41 and 3q22.3 coronary artery disease risk loci are associated with altered cardiac gene expression profiles in normal and diseased heart. Circulation, 124, A12170. [Abstract]
Eglinton, T. W., Roberts, R. L., Pearson, J. F., Barclay, M. L., Ferguson, L. R., Han, D. Y., Frizelle, F. A., & Gearry, R. B. (2011). Clinical and genetic risk factors for perianal Crohn's disease (CD) in a population based cohort. Colorectal Disease, 13(Suppl. s5), 067, (pp. 12). doi: 10.1111/j.1463-1318.2011.02655.x
Wall, C., Skidmore, P., Gearry, R., Pearson, J., Parnell, W., & Joyce, P. (2011). Associations between psycho-social variables and dietary intake. Nutrition & Dietetics, 68(Suppl. 2), (pp. 6). [Abstract]
Harley, J. A., Kennedy, M. A., Doudney, K., Allington, M., Pearson, J., Black, M., & Joyce, P. R. (2011). Antidepressants cause specific changes in the rat peripheral blood transcriptome. Biological Psychiatry. 69(9, Suppl. 1), (pp. 89S). [Abstract]
Conference Contribution - Poster Presentation (not in published proceedings)
Eglinton, T. W., Roberts, R. L., Pearson, J., Ferguson, L., Han, D., Barclay, M. L., Frizelle, F. A., & Gearry, R. B. (2011, November). Clinical and genetic risk factors for Perianal Crohn's disease (CD) in a population based cohort. Poster session presented at the New Zealand Society of Gastroenterology & NZNO Gastroenterology Nurses Section Annual Scientific Meeting, Dunedin, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Pilbrow, A. P., Pearson, J. F., Brown, C. M., McNoe, L., Sweet, W. E., Tang, W. H. W., Black, M. A., Troughton, R. W., Richards, A. M., … Cameron, V. A. (2011, September). Cardiac gene expression profiling. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
2010
Journal - Research Article
Taylor, B. V., Pearson, J. F., Clarke, G., Mason, D. F., Abernethy, D. A., Willoughby, E., & Sabel, C. (2010). MS prevalence in New Zealand, an ethnically and latitudinally diverse country. Multiple Sclerosis, 16(12), 1422-1431. doi: 10.1177/1352458510379614
Scott-Thomas, A. J., Syhre, M., Pattemore, P. K., Epton, M., Laing, R., Pearson, J., & Chambers, S. T. (2010). 2-Aminoacetophenone as a potential breath biomarker for Pseudomonas aeruginosa in the cystic fibrosis lung. BMC Pulmonary Medicine, 10, 56. doi: 10.1186/1471-2466-10-56
Stewart, L. C., Day, A. S., Pearson, J., Barclay, M. L., Gearry, R. B., Roberts, R. L., & Bentley, R. W. (2010). SLC11A1 polymorphisms in inflammatory bowel disease and Mycobacterium avium subspecies paratuberculosis status. World Journal of Gastroenterology, 16(45), 5727-5731. doi: 10.3748/wjg.v16.i45.5727
Bergin, M., Bird, P., Cowan, I., & Pearson, J. F. (2010). Exploring the critical distance and position relationships between the eustachian tube and the internal carotid artery. Otology & Neurotology, 31(9), 1511-1515. doi: 10.1097/MAO.0b013e3181f6c880
Whitehead, C., Lunt, H., Pearson, J. F., & Cawood, T. J. (2010). Is screening for hypothyroidism in the diabetes clinic effective? Practical Diabetes International, 27(3), 113-117. doi: 10.1002/pdi.1458
Spittlehouse, J. K., Pearson, J. F., Luty, S. E., Mulder, R. T., Carter, J. D., McKenzie, J. M., & Joyce, P. R. (2010). Measures of temperament and character are differentially impacted on by depression severity. Journal of Affective Disorders, 126, 140-146. doi: 10.1016/j.jad.2010.03.010
Bentley, R. W., Pearson, J., Gearry, R. B., Barclay, M. L., McKinney, C., Merriman, T. R., & Roberts, R. L. (2010). Association of higher DEFB4 genomic copy number with Crohn's disease. American Journal of Gastroenterology, 105(2), 354-359. doi: 10.1038/ajg.2009.582
Conference Contribution - Published proceedings: Abstract
Feng, S. D. W., MacAskill, M. R., Pitcher, T. L., Melzer, T. R., Pearson, J. F., Graham, C., & Anderson, T. J. (2010). Correlations between ASL blood flow MRI and eye movement abnormalities in Parkinson's disease. In B. Leitch (Ed.), Proceedings of the 28th International Australasian Winter Conference on Brain Research. 28, (pp. 52). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2010.htm
Melzer, T. R., Watts, R., MacAskill, M. R., Pearson, J. F., Keenan, R., Shankaranarayanan, A., … Graham, C., Livingston, L., Dalrymple-Alford, J. C., & Anderson, T. J. (2010). Reduced cerebral perfusion in cognitively impaired Parkinson's disease. In B. Leitch (Ed.), Proceedings of the 28th International Australasian Winter Conference on Brain Research. 28, (pp. 53). AWCBR. Retrieved from http://psy.otago.ac.nz/awcbr/Abstracts/Abstracts2010.htm
Glubb, D. M., Pearson, J., Hollis-Moffatt, J. E., Topless, R. K. G., Merriman, T. R., Simms, L. A., … Barclay, M. L., … Gearry, R. B., … Roberts, R. L. (2010). Extracellular Matrix Protein 1 is associated with ulcerative colitis but is not implicated in Crohn's disease. New Zealand Medical Journal, 123(1327). Retrieved from http://journal.nzma.org.nz/journal/123-1327/4492/content.pdf
Harley, J. A., Doudney, K., Allington, M. A., McNoe, L., Pearson, J., Black, M., Joyce, P. R., & Kennedy, M. A. (2010). Antidepressant specific changes in rat whole blood gene expression identified by gene-chip analysis. Proceedings of the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists New Zealand Annual Scientific Meeting and the 6th Annual Carney Pharmacogenomics Symposium. ASCEPT. Retrieved from http://www.ascept.org.nz/
Melzer, T. R., Watts, R., MacAskill, M. R., Pearson, J., Livingston, L., Graham, C., Keenan, R., … Dalrymple-Alford, J. C., & Anderson, T. J. (2010). Characteristic arterial spin labeling MRI perfusion abnormalities in early, treatment-free Parkinson's disease. New Zealand Medical Journal, 123(1313). Retrieved from http://journal.nzma.org.nz/journal/123-1313/4096/content.pdf
Conference Contribution - Poster Presentation (not in published proceedings)
Thorpe, A., Joyce, P., & Pearson, J. (2010, September). Attitudes of fifty year olds towards aging. Poster session presented at the Fourth Annual Division of Health Sciences Research Forum, Dunedin, New Zealand.
2009
Journal - Research Article
Berry, S. D., Davis, S. R., Beattie, E. M., Thomas, N. L., Burrett, A. K., Ward, H. E., … Pearson, J. F., … Snell, R. G. (2009). Mutation in bovine &beta-carotene oxygenase 2 affects milk color. Genetics, 182, 923-926. doi: 10.1534/genetics.109.101741
Doudney, K., Harley, J. A., Pearson, J. F., Miller, A., Aitchison, A., Kennedy, M. A., Porter, R. J., Elmslie, J. L., & Joyce, P. R. (2009). Upstream genetic variant near INSIG2, influences response to carnitine supplementation in bipolar patients with valproate-induced weight gain. Acta Neuropsychiatrica, 21(3), 133-140. doi: 10.1111/j.1601-5215.2009.00379.x
Conference Contribution - Published proceedings: Abstract
Doudney, K., Harley, J. A., Pearson, J. F., Miller, A., Aitchison, A., Kennedy, M. A., Porter, R. J., Elmslie, J. L., & Joyce, P. R. (2009). Upstream genetic variant near INSIG2 is associated with adipose metabolism in bipolar patients with valproate induced weight gain. Proceedings of the 5th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.otago.ac.nz/christchurch/otago019049.pdf
Harley, J. A., Doudney, K., Allington, M., Pearson, J., Black, M., Joyce, P. R., & Kennedy, M. A. (2009). Blood mRNA changes induced by antidepressants. Proceedings of the 5th Annual Carney Pharmacogenomics Symposium. Retrieved from http://www.otago.ac.nz/christchurch/otago019049.pdf
Clarke, G., Anderson, T., Pearson, J., Mason, D., & Taylor, B. (2009). What is the effect of multiple sclerosis on income and employment in New Zealand? Multiple Sclerosis. 15(Suppl. 2), (pp. S56). [Abstract]
Cameron, V. A., Pilbrow, A. P., Palmer, B. R., Ellis, K. L., Pearson, J., Moravec, C. S., … Troughton, R. W., & Richards, A. M. (2009). Gene polymorphisms in patients with heart failure and acute coronary syndromes. CVD Prevention and Control. 4(Suppl. 1), (pp. S15). [Abstract]
Bentley, R. W., Pearson, J., Gearry, R. B., Barclay, M. L., McKinney, C., Merriman, T. R., & Roberts, R. L. (2009). Association of increased beta-defensin 2 genomic copy number with Crohn's disease. Proceedings of the GASTRO Conference. Retrieved from http://www.gastro2009.org/scien_prog/search.php?navId=244
Volkova, E., Willis, J. A., Gunningham, S. P., Hanrahan, V., Pearson, J., Robinson, B. A., Dachs, G. U., & Currie, M. J. (2009). Role of obesity in colon tumor angiogenesis and cancer progression. Proceedings of the American Association for Cancer Research (AACR) 100th Annual Meeting. Retrieved from http://www.aacrmeetingabstracts.org/
Evans, G. E., Martinez-Conejero, J. A., Benny, P. S., Phillipson, G. T. M., Simòn, C., McNoe, L. A., Pearson, J. F., … Sin, I. L. (2009). Characterising specific cell compartments of the fertile endometrium by gene and protein expression. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Pilbrow, A. P., Pearson, J., Brown, C. M., McNoe, L., Black, M. A., Sweet, W. E., … Troughton, R. W., Richards, A. M., … Cameron, V. A. (2009). Chromosome 6q25.1 and 2q36.3 coronary heart disease risk loci are associated with altered cardiac gene expression profiles in normal heart. Circulation, 120(18, Suppl.), (pp. S564). [Abstract]
Clarke, G., Anderson, T., Pearson, J., Mason, D., & Taylor, B. (2009). What is the effect of multiple sclerosis on employment? Journal of Clinical Neuroscience, 16(11), (pp. 1544). doi: 10.1016/j.jocn.2009.07.079
Taylor, B., Richardson, A., Pearson, J., Mason, D., Willoughby, E., Abernethy, D., Clarke, G., & Sabel, C. (2009). Prevalence of multiple sclerosis in New Zealand. Journal of Clinical Neuroscience. 16(11), (pp. 1529). doi: 10.1016/j.jocn.2009.07.041
Mason, D., Clarke, G., Pearson, J., & Taylor, B. (2009). Disability and MS in New Zealand. Journal of Clinical Neuroscience. 16(11), (pp. 1537). doi: 10.1016/j.jocn.2009.07.061
Conference Contribution - Verbal presentation and other Conference outputs
Clarke, G., Pearson, J., Anderson, T., Mason, D., & Taylor, B. (2009, October). The effect of multiple sclerosis on income and employment in New Zealand. Verbal presentation at the MSRA Progress in MS Research Scientific Conference, Sydney, Australia.
2008
Conference Contribution - Published proceedings: Abstract
Pilbrow, A., Pearson, J., McNoe, L., Black, M., Moravec, C., Sweet, W., … Troughton, R., Richards, M., & Cameron, V. (2008). The chromosome 9p21.3 coronary artery disease risk locus is associated with altered cardiac gene expression in individuals without overt cardiac abnormality. Circulation, 118(18, Suppl.), (pp. S_390-S_391). [Abstract]
2005
Journal - Research Article
Curtis, M. A., Penney, E. B., Pearson, J., Dragunow, M., Connor, B., & Faull, R. L. M. (2005). The distribution of progenitor cells in the subependymal layer of the lateral ventricle in the normal and Huntington's disease human brain. Neuroscience, 132(3), 777-788. doi: 10.1016/j.neuroscience.2004.12.051
2003
Journal - Research Article
Pearson, A. G., Gray, C. W., Pearson, J. F., Greenwood, J. M., During, M. J., & Dragunow, M. (2003). ATF3 enhances c-Jun-mediated neurite sprouting. Molecular Brain Research, 120(1), 38-45. doi: 10.1016/j.molbrainres.2003.09.014
2002
Journal - Research Article
Parmar, P. K., Coates, L. C., Pearson, J. F., Hill, R. M., & Birch, N. P. (2002). Neuroserpin regulates neurite outgrowth in nerve growth factor-treated PC12 cells. Journal of Neurochemistry, 82(6), 1406-1415. doi: 10.1046/j.1471-4159.2002.01100.x
Conference Contribution - Published proceedings: Full paper
Hill, R. M., Coates, L. C., Parmar, P. K., Mezey, E., Pearson, J. F., & Birch, N. P. (2002). Expression and functional characterization of the serine protease inhibitor neuroserpin in endocrine cells. Annals of the New York Academy of Sciences, 971(1), (pp. 406-415). doi: 10.1111/j.1749-6632.2002.tb04503.x
2000
Journal - Research Article
Hill, R. M., Parmar, P. K., Coates, L. C., Mezey, E., Pearson, J. F., & Birch, N. P. (2000). Neuroserpin is expressed in the pituitary and adrenal glands and induces the extension of neurite-like processes in AtT-20 cells. Biochemical Journal, 345(3), 595-601. doi: 10.1042/bj3450595