Associate Professor
Email peter.sykes@otago.ac.nz
Peter joined the Department in 1998 and was Head of Department from 2009 until December 2015.
He completed his undergraduate training in the United Kingdom and specialised in Obstetrics and Gynaecology in New Zealand.
He subsequently completed his sub-specialty training in gynaecological oncology in Melbourne and his interests include gynaecological oncology and advanced preinvasive disease of the genital tract.
Peter is a keen outdoor sports person and enjoys tramping, mountain climbing and surfing.
Publications
Sykes, P., Innes, C., Bell, R., Nip, J., McMenamin, J., McBain, L., Hudson, B., … Te Whaiti, S., Tino, A., Williman, J., Miller, A., & Lawton, B. (2025). Human papillomavirus (HPV) screening with universal access to vaginal self-testing: Outcomes of an implementation trial. BJOG. Advance online publication. doi: 10.1111/1471-0528.18159 Journal - Research Article
Sykes, P., Innes, C., Simcock, B., Lawton, B., & Williman, J. (2025). Realising the promise of HPV vaccination: Data from the national cervical screening and vaccination registers demonstrates the impact of HPV vaccination in Aotearoa New Zealand. Journal of the Royal Society of New Zealand. Advance online publication. doi: 10.1080/03036758.2025.2458028 Journal - Research Article
Rose, S. B., McBain, L., Bell, R., Innes, C., Te Whaiti, S., Tino, A., & Sykes, P. (2024). 'Kind of scared but happy something was detected.': Cross-sectional survey of Let's Test for HPV participants to understand perspectives on an HPV detected result. Australian & New Zealand Journal of Obstetrics & Gynaecology. Advance online publication. doi: 10.1111/ajo.13906 Journal - Research Article
Stylianou, C. E., Wiggins, G. A. R., Lau, V. L., Dennis, J., Shelling, A. N., Wilson, M., Sykes, P., … Pearson, J., & Walker, L. C. (2024). Germline copy number variants and endometrial cancer risk. Human Genetics. Advance online publication. doi: 10.1007/s00439-024-02707-9 Journal - Research Article
Te Whaiti, S., Sykes, P. H., Scott, N., & Simcock, B. (2024). Let's use an equity framework to improve research, its design, implementation, and community. International Journal of Gynecological Cancer. Advance online publication. doi: 10.1136/ijgc-2024-005938 Journal - Research Other
2025
Journal - Research Article
Sykes, P., Innes, C., Bell, R., Nip, J., McMenamin, J., McBain, L., Hudson, B., … Te Whaiti, S., Tino, A., Williman, J., Miller, A., & Lawton, B. (2025). Human papillomavirus (HPV) screening with universal access to vaginal self-testing: Outcomes of an implementation trial. BJOG. Advance online publication. doi: 10.1111/1471-0528.18159
Sykes, P., Innes, C., Simcock, B., Lawton, B., & Williman, J. (2025). Realising the promise of HPV vaccination: Data from the national cervical screening and vaccination registers demonstrates the impact of HPV vaccination in Aotearoa New Zealand. Journal of the Royal Society of New Zealand. Advance online publication. doi: 10.1080/03036758.2025.2458028
2024
Journal - Research Article
Rose, S. B., McBain, L., Bell, R., Innes, C., Te Whaiti, S., Tino, A., & Sykes, P. (2024). 'Kind of scared but happy something was detected.': Cross-sectional survey of Let's Test for HPV participants to understand perspectives on an HPV detected result. Australian & New Zealand Journal of Obstetrics & Gynaecology. Advance online publication. doi: 10.1111/ajo.13906
Stylianou, C. E., Wiggins, G. A. R., Lau, V. L., Dennis, J., Shelling, A. N., Wilson, M., Sykes, P., … Pearson, J., & Walker, L. C. (2024). Germline copy number variants and endometrial cancer risk. Human Genetics. Advance online publication. doi: 10.1007/s00439-024-02707-9
Rose, S. B., McBain, L., Garrett, S. M., Bell, R., Innes, C., Te Whaiti, S., Tino, A., & Sykes, P. (2024). 'I felt so empowered, respected and shame free.': Let's test for HPV participants' experience of HPV primary screening. Journal of Primary Health Care. Advance online publication. doi: 10.1071/HC24118
Chitcholtan, K., Singh, M., Tino, A., Garrill, A., & Sykes, P. (2024). Effects of resveratrol on in vivo ovarian cancer cells implanted on the chorioallantoic membrane (CAM) of a chicken embryo model. International Journal of Molecular Sciences, 25, 4374. doi: 10.3390/ijms25084374
Ingamells, S., Bell, R., Nip, J., Innes, C., Te Whaiti, S., Tino, A., McBain, L., McMenamin, J., Hudson, B., … Lawton, B., & Sykes, P. (2024). Perceived barriers to self-collected HPV testing for cervical cancer screening, and knowledge of HPV: A survey of primary healthcare smear-takers across Aotearoa New Zealand. New Zealand Medical Journal/Te ara tika o te hauora hapori, 137(1590), 57-76. Retrieved from https://www.nzmj.org.nz/
Journal - Research Other
Te Whaiti, S., Sykes, P. H., Scott, N., & Simcock, B. (2024). Let's use an equity framework to improve research, its design, implementation, and community. International Journal of Gynecological Cancer. Advance online publication. doi: 10.1136/ijgc-2024-005938
Conference Contribution - Published proceedings: Abstract
McBain, L., Innes, C., Bell, R., Sykes, P., & Rose, S. B. (2024). Experience of HPV primary screening utilising self-testing: A cross-sectional survey of 'Lets's test for HPV' study participants in Aotearoa New Zealand. Australian Journal of Primary Health, 30, (pp. 25). doi: 10.1071/PYv30n4abs
2023
Journal - Research Article
Nagao, S., Fujiwara, K., Yamamoto, K., Tanabe, H., Okamoto, A., Takehara, K., … Sykes, P., … Enomoto, T. (2023). Intraperitoneal carboplatin for ovarian cancer - A phase 2/3 trial. NEJM Evidence, 2(5). doi: 10.1056/EVIDoa2200225
Majid, M. A., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2023). The effects of the obesity-related hormones leptin, insulin, IGF-I and adiponectin on Ishikawa and HEC-1A, MCF-7 and SKOV-3 cancer cell lines. EC Gynaecology, 12(8). Retrieved from https://ecronicon.net/ec_gynaecology
Chitcholtan, K., Dyer, A., & Sykes, P. (2023). Predicting tumour progression of ID-8 syngeneic mouse ovarian cancer with blood biomarkers fo CA-125, IL-6 and VEGF: A prospective laboratory-based study. Clinical & Experimental Obstetrics & Gynaecology, 50(10), 212. doi: 10.31083/j.ceog5010212
Saito, M., Rajesh, A., Innes, C., van der Griend, R., Fitzgerald, P., Simcock, B., Sykes, P., & Hibma, M. (2023). The high-risk human papillomavirus type influences the tissue microenvironment in cervical intraepithelial neoplasia grade 2. Viruses, 15, 1953. doi: 10.3390/v15091953
Mertens, R. C. E., Sykes, P. H., Innes, C. R., Simcock, B. J., & Petrich, S. (2023). Endometrial cancer diagnoses prompted by routine cervical cytology: A retrospective case study. New Zealand Medical Journal/Te ara tika o te hauora hapori, 136(1581), 56-65. Retrieved from https://journal.nzma.org.nz/
Borchowsky, K., Rush, M., Mullally, T., McBain, L., Hudson, B., McMenamin, J., … Sykes, P., & Garrett, S. (2023). Primary care experiences in the 'Let's test for HPV' study: A qualitative analysis. Journal of Primary Health Care, 15(2), 147-154. doi: 10.1071/HC23038
Kumar, D., Moghiseh, M., Chitcholtan, K., Mutreja, I., Lowe, C., Kaushik, A., Butler, A., Sykes, P., Anderson, N., & Raja, A. (2023). LHRH conjugated gold nanoparticles assisted efficient ovarian cancer targeting evaluated via spectral photon-counting CT imaging: A proof-of-concept research. Journal of Materials Chemistry B, 11, 1916-1928. doi: 10.1039/d2tb02416k
Cabasag, C. J., Arnold, M., Rutherford, M., Ferlay, J., Bardot, A., Morgan, E., … Sykes, P., … Soerjomataram, I. (2023). Shifting incidence and survival of epithelial ovarian cancer (1995-2014): A SurvMark-2 study. International Journal of Cancer, 152, 1763-1777. doi: 10.1002/ijc.34403
Journal - Research Other
Lawton, B., MacDonald, E. J., Storey, F., Stanton, J.-A., Adcock, A., Gibson, M., … King, F., … Watson, H., Bennett, M., Lambert, C. S., Geller, S., Paasi, I., Hibma, M., Sykes, P., Hawkes, D., & Saville, M. (2023). A model for empowering rural solutions for cervical cancer prevention (He Tapu Te Whare Tangata): Protocol for a cluster randomized crossover trial. JMIR Research Protocols, 12, e51643. doi: 10.2196/51643
Yunianto, I., Currie, M., Chitcholtan, K., & Sykes, P. (2023). Potential drug repurposing of ruxolitinib to inhibit the JAK/STAT pathway for the treatment of patients with epithelial ovarian cancer. Journal of Obstetrics & Gynaecology Research, 49, 2563-2574. doi: 10.1111/jog.15761
Gibson-Helm, M., Slater, T., MacDonald, E. J., Stevenson, K., Adcock, A., Geller, S., … Hibma, M., Sykes, P., … Lawton, B. (2023). Te Ara Waiora-Implementing human papillomavirus (HPV) primary testing to prevent cervical cancer in Aotearoa New Zealand: A protocol for a non-inferiority trial. PLoS ONE, 18(3), e0280643. doi: 10.1371/journal.pone.0280643
Journal - Professional & Other Non-Research Articles
Allanson, E. R., Burling, M., Simcock, B., Nicklin, J., & Sykes, P. H. (2023). The Australian Society of Gynaecological Oncology Western Pacific Liaison Group [Corners of the world]. International Journal of Gynecological Cancer, 33(11), 1819-1820. doi: 10.1136/ijgc-2023-004845
2022
Journal - Research Article
Saito, M., Rajesh, A., Innes, C., van der Griend, R., Fitzgerald, P., Simcock, B., Sykes, P., & Hibma, M. (2022). Blimp-1 is a prognostic indicator for progression of cervical intraepithelial neoplasia grade 2. Journal of Cancer Research & Clinical Oncology, 148, 1991-2002. doi: 10.1007/s00432-022-03993-4
Dunn, E., Chitcholtan, K., Sykes, P., & Garrill, A. (2022). The anti-proliferative effect of PI3K/mTOR and ERK inhibition in monolayer and three-dimensional ovarian cancer cell models. Cancers, 14, 395. doi: 10.3390/cancers14020395
Sarwar, M., Sykes, P. H., Chitcholtan, K., & Evans, J. J. (2022). Collagen I dysregulation is pivotal for ovarian cancer progression. Tissue & Cell, 74, 101704. doi: 10.1016/j.tice.2021.101704
Sykes, P. H., Simcock, B. J., Innes, C. R., Harker, D., Williman, J. A., Whitehead, M., van der Griend, R. A., … Hibma, M., … Petrich, S., … Sadler, L. (2022). Predicting regression of cervical intraepithelial neoplasia grade 2 in women under 25 years. American Journal of Obstetrics & Gynecology, 226, 222.e1-222.e13. doi: 10.1016/j.ajog.2021.09.009
Journal - Research Other
Taghavi, K., Lamb, J., MacNab, H., Innes, C., Peddie, D., Harker, D., Williman, J., Sykes, P., & Simcock, B. (2022). Patient choice may improve adherence to follow-up in cervical screening: A randomised-control trial. New Zealand Medical Journal, 135(1550), 134-144. Retrieved from https://journal.nzma.org.nz/
Boo, M., Sykes, P., & Simcock, B. (2022). Use of direct oral anticoagulants for postoperative venous thromboembolism prophylaxis after surgery for gynecologic malignancies. International Journal of Gynecological Cancer, 32, 189-194. doi: 10.1136/ijgc-2021-003006
Conference Contribution - Verbal presentation and other Conference outputs
Saito, M., Rajesh, A., Innes, C., van der Griend, R., Fitzgerald, P., Simcock, B., Sykes, P., & Hibma, M. (2022, August). The immune microenvironment in progression and regression of cervical intraepithelial neoplasia grade 2. Verbal presentation at the Cancer Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.
2021
Journal - Research Article
Edmonson, R. J., O'Connell, R. L., Banerjee, S., Mileshkin, L., Sykes, P., Beale, P., … on behalf of PARAGON Investigators. (2021). Phase 2 study of anastrozole in rare cohorts of patients with estrogen receptor/progesterone receptor positive leiomyosarcomas and carcinosarcomas of the uterine corpus: The PARAGON trial (ANZGOG 0903). Gynecologic Oncology, 163, 524-530. doi: 10.1016/j.ygyno.2021.09.010
Janda, M., Robledo, K. P., Gebski, V., Armes, J. E., Alizart, M., Cummings, M., … Sykes, P., … Obermair, A. (2021). Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: Results of a randomized clinical trial. Gynecologic Oncology, 161(1), 143-151. doi: 10.1016/j.ygyno.2021.01.029
Sarwar, M., Sykes, P. H., Chitcholtan, K., & Evans, J. J. (2021). Deciphering biophysical modulation in ovarian cancer cells. Cell Biochemistry & Biophysics, 79, 375-386. doi: 10.1007/s12013-020-00964-9
2020
Journal - Research Article
Goyani, A. D., Innes, C. R., Simcock, B. J., Harker, D., Dudley, N. M., Eva, L., Bergzoll, C., MacNab, H., & Sykes, P. H. (2020). Trends in the diagnosis of high-grade cervical abnormalities in young women in the post-vaccination era. New Zealand Medical Journal, 133(1524), 50-63. Retrieved from https://www.nzma.org.nz/journal
Cohen, P. A., Leung, Y., Anderson, L., van der Griend, R., Chivers, P., Bilic, S., … Harker, D., … Simcock, B., … Sykes, P., … Wrede, C. D. H. (2020). Excisional treatment comparison for in situ endocervical adenocarcinoma (EXCISE): A phase 2 pilot randomized controlled trial to compare histopathological margin status, specimen size and fragmentation after loop electrosurgical excision procedure and cold knife cone biopsy. Gynecologic Oncology, 159, 623-629. doi: 10.1016/j.ygyno.2020.09.053
Norell, C. H., Butler, J., Farrell, R., Altman, A., Bentley, J., Cabasag, C. J., … Sykes, P. H., … Harrison, S. (2020). Exploring international differences in ovarian cancer treatment: A comparison of clinical practice guidelines and patterns of care. International Journal of Gynecological Cancer, 30, 1748-1756. doi: 10.1136/ijgc-2020-001403
Chitcholtan, K., Harker, D., Simcock, B., & Sykes, P. (2020). Sensitivity of EGFR/HER-2 positive cells isolated from ascitic fluid of advanced ovarian cancer patients to EGFR/HER-2 inhibitors. Applied Sciences, 10(7), 2343. doi: 10.3390/app10072343
Dempster-Rivett, K., Innes, C. R., Simcock, B. J., Harker, D., Williman, J. A., Van Der Griend, R. A., Whitehead, M., Hibma, M., … Petrich, S., Faherty, J., … Sykes, P. H. (2020). Evaluation of guidelines for observational management of cervical intraepithelial neoplasia 2 in young women. American Journal of Obstetrics & Gynecology, 223, 408.e1-408.e11. doi: 10.1016/j.ajog.2020.02.029
Cabasag, C. J., Butler, J., Arnold, M., Rutherford, M., Bardot, A., Ferlay, J., … Sykes, P., … Soerjomataram, I. (2020). Exploring variations in ovarian cancer survival by age and stage (ICBP SurvMark-2): A population-based study. Gynecologic Oncology, 157, 234-244. doi: 10.1016/j.ygyno.2019.12.047
Innes, C. R. H., Williman, J. A., Simcock, B. J., Hider, P., Sage, M., Dempster-Rivett, K., … Sykes, P. H. (2020). Impact of human papillomavirus vaccination on rates of abnormal cervical cytology and histology in young New Zealand women. New Zealand Medical Journal, 133(1508), 72-84. Retrieved from https://www.nzma.org.nz/journal
Journal - Research Other
Sarwar, M., Sykes, P., & Evans, J. J. (2020). A doctrine of ovarian cancer translational research needs revisiting. International Journal of Cancer Management, 13(8), e105436. doi: 10.5812/ijcm.105436
Butler, J., Finley, C., Norell, C. H., Harrison, S., Bryant, H., Achiam, M. P., … Sykes, P., & Thomas, R. (2020). New approaches to cancer care in a COVID-19 world. Lancet Oncology, 21(7), e339-e340. doi: 10.1016/S1470-2045(20)30340-5
Sarwar, M., Sykes, P. H., Chitcholtan, K., & Evans, J. J. (2020). Extracellular biophysical environment: Guilty of being a modulator of drug sensitivity in ovarian cancer cells. Biochemical & Biophysical Research Communications, 527(1), 180-186. doi: 10.1016/j.bbrc.2020.04.107
2019
Journal - Research Article
Yeoh, S., Simcock, B., Innes, C., Mclachlan, J., Harker, D., & Sykes, P. (2019). Trends in the overall survival rates in women with advanced ovarian cancer in a single tertiary centre in New Zealand. Australian & New Zealand Journal of Obstetrics & Gynaecology, 59, 861-866. doi: 10.1111/ajo.13076
Tang, M., O'Connell, R. L., Amant, F., Beale, P., McNally, O., Sjoquist, K. M., … Sykes, P., … Friedlander, M. (2019). PARAGON: A phase II study of anastrozole in patients with estrogen receptor-positive recurrent/metastatic low-grade ovarian cancers and serous borderline ovarian tumors. Gynecologic Oncology, 154, 531-538. doi: 10.1016/j.ygyno.2019.06.011
Cohen, P. A., Powell, A., Böhm, S., Gilks, C. B., Stewart, C. J. R., Meniawy, T. M., … van der Griend, R., … the HGSC CRS Collaborative Network, including Simcock, B., Sykes, P., Vaughan, M. M., & Singh, N. (2019). Pathological chemotherapy response score is prognostic in tubo-ovarian high-grade serous carcinoma: A systematic review and meta-analysis of individual patient data. Gynecologic Oncology, 154, 441-448. doi: 10.1016/j.ygyno.2019.04.679
Ekeroma, A. J., Naik, S., & Sykes, P. (2019). Systematic review of effective cervical cancer treatments in Small Island Developing States: A narrative synthesis. Pacific Journal of Reproductive Health, (8), 462-474. doi: 10.18313/pjrh.2019.906
Sykes, P., Eva, L., van der Griend, R., McNally, O., Blomfield, P., Brand, A., … Petrich, S., Kenwright, D., … Innes, C., Harker, D., … Simcock, B. (2019). Pathological process has a crucial role in sentinel node biopsy for vulvar cancer. Gynecologic Oncology, 153, 292-296. doi: 10.1016/j.ygyno.2019.02.012
Fraser, K., Tan, A. L., Innes, C., Stephens, R., Tristram, A., Petrich, S., Lintott, C., Sykes, P. H., … Simcock, B. (2019). Patterns of referral and uptake of BReast CAncer (BRCA) gene testing of eligible women with ovarian cancer in New Zealand. New Zealand Medical Journal, 132(1490), 26-35. Retrieved from https://www.nzma.org.nz/journal
Adcock, A., Cram, F., Lawton, B., Geller, S., Hibma, M., Sykes, P., … Hart, S. (2019). Acceptability of self-taken vaginal HPV sample for cervical screening among an under-screened Indigenous population. Australian & New Zealand Journal of Obstetrics & Gynaecology, 59, 301-307. doi: 10.1111/ajo.12933
Sarwar, M., Sykes, P. H., Chitcholtan, K., Alkaisi, M. M., & Evans, J. J. (2019). The extracellular topographical environment influences ovarian cancer cell behaviour. Biochemical & Biophysical Research Communications, 508, 1188-1194. doi: 10.1016/j.bbrc.2018.12.067
Journal - Research Other
Evans, J. J., Alkaisi, M. M., & Sykes, P. H. (2019). Tumour initiation: A discussion on evidence for a "load-trigger" mechanism [Hypothesis]. Cell Biochemistry & Biophysics, 77, 293-308. doi: 10.1007/s12013-019-00888-z
Conference Contribution - Published proceedings: Abstract
Bowden, V., Cuddihy, S., Yeoh, S., Innes, C., van der Griend, R., Simcock, B., Sykes, P., & Harker, D. (2019). Audit of intraoperative ovarian frozen section accuracy in a single tertiary centre. Australian & New Zealand Journal of Obstetrics & Gynaecology, 59(Suppl. 1), (pp. 53-54). doi: 10.1111/ajo.13067
2018
Journal - Research Article
Innes, C. R., Sykes, P. H., Harker, D., Williman, J. A., Van der Griend, R. A., Whitehead, M., Hibma, M., … Petrich, S., Faherty, J., … Simcock, B. J. (2018). Changes in human papillomavirus genotypes associated with cervical intraepithelial neoplasia grade 2 lesions in a cohort of young women (2013–2016). Papillomavirus Research, 6, 77-82. doi: 10.1016/j.pvr.2018.10.010
Hider, P., Dempster-Rivett, K., Williman, J., Dempster-Rivett, M., Sadler, L., McLeod, M., Miller, A., & Sykes, P. (2018). A review of cervical cancer occurrences in New Zealand 2008–2012. New Zealand Medical Journal, 131(1472), 53-63. Retrieved from https://www.nzma.org.nz/journal
Hassan, W., Chitcholtan, K., Sykes, P., & Garrill, A. (2018). Ascitic fluid from advanced ovarian cancer patients compromises the activity of receptor tyrosine kinase inhibitors in 3D cell clusters of ovarian cancer cells. Cancer Letters, 420, 168-181. doi: 10.1016/j.canlet.2018.02.013
Evans, G. E., Phillipson, G. T. M., Sykes, P. H., McNoe, L. A., Print, C. G., & Evans, J. J. (2018). Does the endometrial gene expression of fertile women vary within and between cycles? Human Reproduction, 33(3), 452-463. doi: 10.1093/humrep/dex385
Conference Contribution - Published proceedings: Abstract
Tino, A., Dachs, G., Sykes, P., Evans, J., & Chitcholtan, K. (2018). Ovarian cancer cell lines grown in a three dimensional collagen model respond differentially to lysophosphatidic acid and tumour necrosis factor-alpha. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/
Sarwar, M., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2018). Microenvironment biophysics: It is vital to tumour cell behaviour including resistance to chemotherapy. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/
Conference Contribution - Poster Presentation (not in published proceedings)
Sarwar, M., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2018, August). Unseen to be seen: A hidden microenvironment regulates ovarian cancer cell behaviour. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Chitcholtan, K., Harker, D., Simcock, B., & Sykes, P. (2018, August). Inhibition of EGFR/HER-2 affects growth of ascitic ovarian cancer cells in vitro study. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.
Conference Contribution - Verbal presentation and other Conference outputs
Evans, J. J., Alkaisi, M. M., & Sykes, P. H. (2018, August). An alliance of biophysics, biochemistry and genetics initiates cancers. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2017
Journal - Research Article
Janda, M., Gebski, V., Davies, L. C., Forder, P., Brand, A., Hogg, R., … Sykes, P., … Simcock, B., … Obermair, A. (2017). Effect of total laparoscopic hysterectomy vs total abdominal hysterectomy on disease-free survival among women with stage 1 endometrial cancer: A randomised clinical trial. JAMA, 317(12), 1224-1233. doi: 10.1001/jama.2017.2068
Kumar, D., Mutreja, I., Chitcholtan, K., & Sykes, P. (2017). Cytotoxicity and cellular uptake of different sized gold nanoparticles in ovarian cancer cells. Nanotechnology, 28, 475101. doi: 10.1088/1361-6528/aa935e
Jamieson, A., Sykes, P., Eva, L., Bergzoll, C., & Simcock, B. (2017). Subtypes of stage IV ovarian cancer: Response to treatment and patterns of disease recurrence. Gynecologic Oncology, 146(2), 273-278. doi: 10.1016/j.ygyno.2017.05.023
Lindemann, K., Kok, P.-S., Stockler, M., Sykes, P., & Brand, A. (2017). Enhanced recovery after surgery for suspected ovarian malignancy: A survey of perioperative practice among gynecologic oncologists in Australia and New Zealand to inform a clinical trial. International Journal of Gynecological Cancer, 27(5), 1046-1050. doi: 10.1097/igc.0000000000000982
Taghavi, K., Morell, S., Lamb, J., MacNab, H., Innes, C., Coffey, K., Williman, J., Simcock, B., & Sykes, P. (2017). Initial observation of CIN2 does not appear to reduce quality of life in women under 25 years of age. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(4), 473-478. doi: 10.1111/ajo.12633
Tan, L. H., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2017). Cell-like features imprinted in the physical nano- and micro-topography of the environment modify the responses to anti-cancer drugs of endometrial cancer cells. Biofabrication, 9(1), 015017. doi: 10.1088/1758-5090/aa5c9a
Journal - Research Other
Cohen, P., Brand, A., Sykes, P., Wrede, D. C. H., McNally, O., Eva, L., … Stoyles, P. (2017). Excisional treatment in women with cervical adenocarcinoma in situ (AIS): A prospective randomised controlled non-inferiority trial to compare AIS persistence/recurrence after loop electrosurgical excision procedure with cold knife cone biopsy: Protocol for a pilot study. BMJ Open, 7, e017576. doi: 10.1136/bmjopen-2017-017576
Conference Contribution - Published proceedings: Abstract
Adams, F., Sykes, P., Simcock, B., MacNab, H., Innes, C., & Scowcroft, H. (2017). Rates of high grade histology (CIN grade 2 or 3) in women over 30 years referred with low grade cervical cytology and the role of hrHPV. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(Suppl. 1), (pp. 23-24). doi: 10.1111/ajo.12724
Harlow, K., Sykes, P., & De Silva, S. (2017). Attempted implementation of the new Ministry of Health High Suspicion of Cancer definitions for gynaecological malignancies on referrals from primary care to a tertiary gynaecology service in New Zealand: A prospective audit. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(Suppl. 1), (pp. 47). doi: 10.1111/ajo.12725
Yunianto, I., Chitcholtan, K., Currie, M., & Sykes, P. (2017). JAK/STAT pathway inhibition for the treatment of ovarian cancer. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 98). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html
Simcock, B., Innes, C., Sykes, P., Harker, D., Williman, J., van der Griend, R., … Bergzoll, C., Petrich, S., & Lawton, B. (2017). Changing face of HPV in CIN2 in young New Zealand women. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(Suppl. 1), (pp. 62). doi: 10.1111/ajo.12725
Innes, C., Sykes, P., Williman, J., Dempster-Rivett, K., Simcock, B., Hider, P., & Lawton, B. (2017). Impact of HPV vaccination on rates of high grade cervical abnormalities in young NZ women: Register data matching study. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(Suppl. 1), (pp. 6). doi: 10.1111/ajo.12723
Dempster-Rivett, K., Sykes, P., Williman, J., Hider, P., & Dempster-Rivett, M. (2017). Review of cervical cancer cases in New Zealand from 2008-2012 in relation to cervical screening history. Australian & New Zealand Journal of Obstetrics & Gynaecology, 57(Suppl. 1), (pp. 40). doi: 10.1111/ajo.12725
Raja, A. Y., Moghiesh, M., Kumar, D., Sykes, P., Butler, A. P., & Anderson, N. (2017). Effect of size and concentration of gold nanoparticles on spectral CT imaging of cancer cells. Proceedings of the 8th International Conference on Advanced Materials and Nanotechnology (AMN8). (pp. 105). Retrieved from http://confer.co.nz/amn8/
Conference Contribution - Verbal presentation and other Conference outputs
Simcock, B. J., Sykes, P. H., Innes, C. R. H., Lawton, B., Dudley, N., & van der Griend, R. (2017, March). CIN3MA: Observational management of CIN3 in women under 25 years. Verbal presentation at the Australian Society for Colposcopy and Cervical Pathology (ASCCP) XXVth Scientific Meeting, Sydney, Australia.
Sykes, P., Innes, C. R. H., van der Griend, R., Fitzgerald, P., & Simcock, B. (2017, March). Decreasing prevalence of HPV16 & 18 genotypes in young New Zealand women with biopsy-diagnosed CIN2. Verbal presentation at the Australian Society for Colposcopy and Cervical Pathology (ASCCP) XXVth Scientific Meeting, Sydney, Australia.
Dempster-Rivett, K., Innes, C. R., Simcock, B., & Sykes, P. (2017, March). The reliability of colposcopy and cervical cytology in observational management of CIN 2 in women under 25. Verbal presentation at the Australian Society for Colposcopy and Cervical Pathology (ASCCP) XXVth Scientific Meeting, Sydney, Australia.
Sarwar, M., Chitcholtan, K., Alkaisi, M. M., Sykes, P. H., & Evans, J. J. (2017, September). The cell-environment handshake: An interaction that regulates gene expression. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2016
Journal - Research Article
Tino, A. B., Chitcholtan, K., Sykes, P. H., & Garrill, A. (2016). Resveratrol and acetyl-resveratrol modulate activity of VEGF and IL-8 in ovarian cancer cell aggregates via attenuation of the NF-κB protein. Journal of Ovarian Research, 9, 84. doi: 10.1186/s13048-016-0293-0
Hassan, W., Chitcholtan, K., Sykes, P., & Garrill, A. (2016). A combination of two receptor tyrosine kinase inhibitors, canertinib and PHA665752 comprises ovarian cancer cell growth in 3D cell models. Oncology & Therapy, 4(2), 257-274. doi: 10.1007/s40487-016-0031-1
Kumar, D., Mutreja, I., & Sykes, P. (2016). Seed mediated synthesis of highly mono-dispersed gold nanoparticles in the presence of hydroquinone. Nanotechnology, 27, 355601. doi: 10.1088/0957-4484/27/35/355601
Stravens, M., Short, J., Johnson, K., Simcock, B., Shand, B., McGeoch, G., & Sykes, P. (2016). Management of postmenopausal bleeding by general practitioners in a community setting: An observational study. New Zealand Medical Journal, 129(1434), 59-68. Retrieved from http://www.nzma.org.nz/journal
Journal - Research Other
Sykes, P., Innes, C., Harker, D., Whitehead, M., van der Griend, R., Lawton, B., Hibma, M., … Petrich, S., Faherty, J., Bergzoll, C., … Parker, C., Sadler, L., & Simcock, B. (2016). Observational management of CIN 2 in young women: A prospective multicenter trial. Journal of Lower Genital Tract Disease, 20(4), 343-347. doi: 10.1097/lgt.0000000000000244
Conference Contribution - Published proceedings: Abstract
Saito, M., Budhwani, M., Coffey, K., Sykes, P., & Hibma, M. (2016). Immunological markers of persistence & regression in cervical intraepithelial neoplasia grade 2 in women under 25. European Journal of Immunology, 46(Suppl. 1), (pp. 217-218). doi: 10.1002/eji.201670200
2015
Journal - Research Article
Hogg, S. J., Chitcholtan, K., Hassan, W., Sykes, P. H., & Garrill, A. (2015). Resveratrol, acetyl-resveratrol, and polydatin exhibit antigrowth activity against 3D cell aggregates of the SKOV-3 and OVCAR-8 ovarian cancer cell lines. Obstetrics & Gynecology International, 2015, 279591. doi: 10.1155/2015/279591
Tan, L. H., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2015). The characteristics of Ishikawa endometrial cancer cells are modified by substrate topography with cell-like features and the polymer surface. International Journal of Nanomedicine, 10, 4883-4895. doi: 10.2147/ijn.s86336
Hogg, S. J., Evans, J. J., Sykes, P. H., & Chitcholtan, K. (2015). A method to investigate the anti-metabolic activity of anti-cancer agents on ovarian cancer cells cultured in a 96-well high throughput format. Journal of Ovarian Research, 8, 43. doi: 10.1186/s13048-015-0172-0
Wilkinson, T. M., Sykes, P. H. H., Simcock, B., & Petrich, S. (2015). Recurrence of high-grade cervical abnormalities following conservative management of cervical intraepithelial neoplasia grade 2. American Journal of Obstetrics & Gynecology, 212(6), 769.e1-769.e7. doi: 10.1016/j.ajog.2015.01.010
Slatter, T. L., Hsia, H., Samaranayaka, A., Sykes, P., Clow, W., Devenish, C. J., … Royds, J. A., … Hung, N. A. (2015). Loss of ATRX and DAXX expression identifies poor prognosis for smooth muscle tumours of uncertain malignant potential and early stage uterine leiomyosarcoma. Journal of Pathology: Clinical Research, 1(2), 95-105. doi: 10.1002/cjp2.11
Journal - Research Other
Taghavi, K., Sykes, P., Innes, C., Gibbs, D., Hunter, L. A., McBurnie, W., & Simcock, B. (2015). Wrong place at the wrong time: A case of cervical embryonal rhabdomyosarcoma in pregnancy. Gynecologic Oncology Reports, 12, 77-79. doi: 10.1016/j.gore.2015.04.001
Conference Contribution - Verbal presentation and other Conference outputs
Tan, L. H., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2015, August-September). Functioning of Ishikawa cancer cells is dependent on the physical microenvironment, which can modify genetic activities. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2014
Journal - Research Article
Lawton, B., Filoche, S. K., Rose, S. B., Stanley, J., Garrett, S., Robson, B., Brown, S., & Sykes, P. (2014). Uterine cancer: Exploring access to services in the public health system. Australian & New Zealand Journal of Obstetrics & Gynaecology, 54(5), 457-461. doi: 10.1111/ajo.12237
Amant, F., Floquet, A., Friedlander, M., Kristensen, G., Mahner, S., Nam, E. J., … Sykes, P., … Seddon, B. (2014). Gynecological Cancer InterGroup (GCIG) consensus review for endometrial stromal sarcoma. International Journal of Gynecological Cancer, 24(9, Suppl. 3), S67-S72. doi: 10.1097/igc.0000000000000205
Sykes, P., Gopala, K., Tan, A. L., Kenwright, D., Petrich, S., Molijn, A., & Chen, J. (2014). Type distribution of human papillomavirus among adult women diagnosed with invasive cervical cancer (stage 1b or higher) in New Zealand. BMC Infectious Diseases, 14, 374. doi: 10.1186/1471-2334-14-374
Evans, G. E., Martínez-Conejero, J. A., Phillipson, G. T. M., Sykes, P. H., Sin, I. L., Lam, E. Y. N., … Evans, J. J. (2014). In the secretory endometria of women, luminal epithelia exhibit gene and protein expressions that differ from those of glandular epithelia. Fertility & Sterility, 102(1), 307-317. doi: 10.1016/j.fertnstert.2014.04.005
Journal - Research Other
Sykes, P. (2014). [Review of the book The rise and fall of National Women’s Hospital: A history]. New Zealand Medical Journal, 127(1394). Retrieved from http://www.nzma.org.nz/journal
Conference Contribution - Published proceedings: Abstract
Evans, J. J., Tan, L. H., Sykes, P. H., & Alkaisi, M. M. (2014). Topography of the microenvironment determines cancer cell behaviour. Endocrine Reviews, 35(3, Suppl.), MON-315. Retrieved from http://press.endocrine.org/series/endo-meetings
Evans, J. J., Majid, M., Chitcholtan, K., & Sykes, P. H. (2014). Responses of proliferation and VEGF secretion by Ishikawa cells are not parallel when exposed to leptin and adiponectin. Endocrine Reviews, 35(3, Suppl.), MON-0306. Retrieved from http://press.endocrine.org/series/endo-meetings
Conference Contribution - Poster Presentation (not in published proceedings)
Chitcholtan, K., Evans, J., & Sykes, P. (2014, November). Inhibition of EGFR/HER-2 affects growth of ascitic ovarian cancer cells in vitro study. Poster session presented at the 15th Biennial Meeting of the International Gynecologic Cancer Society (IGCS), Melbourne, Australia.
Majid, M. A., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2014, November). Growth factors modulate endometrium cancer cells' proliferation and VEGF secretion. Poster session presented at the 15th Biennial Meeting of the International Gynecologic Cancer Society (IGCS), Melbourne, Australia.
2013
Chapter in Book - Other
Sykes, P. (2013). Obstetrics and Gynaecology. In P. Joyce, G. Nicholls, K. Thomas & T. Wilkinson (Eds.), The Christchurch experience: 40 years of research and teaching. (pp. 33-37). Christchurch, New Zealand: University of Otago.
Journal - Research Article
Kang, M. Y., Sykes, P., Herbison, P., & Petrich, S. (2013). Retrospective analysis on timeframes of referral, diagnosis and treatment of patients with endometrial carcinomas in Dunedin Hospital, 2008–2011. New Zealand Medical Journal, 126(1384). Retrieved from http://www.nzma.org.nz/journal
Chitcholtan, K., Asselin, E., Parent, S., Sykes, P. H., & Evans, J. J. (2013). Differences in growth properties of endometrial cancer in three dimensional (3D) culture and 2D cell monolayer. Experimental Cell Research, 319(1), 75-87. doi: 10.1016/j.yexcr.2012.09.012
Conference Contribution - Verbal presentation and other Conference outputs
Tan, T., Sykes, P. H., Alkaisi, M. M., & Evans, J. J. (2013, August). Behaviour of cancer cells on a surface imprinted with their own features. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
Majid, M., Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2013, August). Adipokines alter behaviour of endometrial cancer cells. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2012
Journal - Research Article
Kondalsamy-Chennakesavan, S., Janda, M., Gebski, V., Baker, J., Brand, A., Hogg, R., … Sykes, P., … Simcock, B., … Obermair, A. (2012). Risk factors to predict the incidence of surgical adverse events following open or laparoscopic surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial. European Journal of Cancer, 48(14), 2155-2162. doi: 10.1016/j.ejca.2012.03.013
Obermair, A., Janda, M., Baker, J., Kondalsamy-Chennakesavan, S., Brand, A., Hogg, R., … Sykes, P., … Simcock, B., … Gebski, V. (2012). Improved surgical safety after laparoscopic compared to open surgery for apparent early stage endometrial cancer: Results from a randomised controlled trial. European Journal of Cancer, 48(8), 1147-1153. doi: 10.1016/j.ejca.2012.02.055
Lawton, B. A., Rose, S. B., Pullon, S., Stanley, J., Garrett, S., Sykes, P., Cormack, D., Robson, B., Langdana, F., Cooper, A., & Filoche, S. K. (2012). The impact of outpatient booking systems on waiting times for investigation of suspected cancer: The case of post-menopausal bleeding. Clinical Ovarian & Other Gynecologic Cancer, 5(2), 87-93. doi: 10.1016/j.cogc.2013.06.001
Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2012). The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer. Journal of Translational Medicine, 10(1), 38-53. doi: 10.1186/1479-5876-10-38
Sykes, P., Vaughan, M., Chrystal, K., Ehrenberg, N., Hefford, M., Hutchings, S., … Ngan Kee, D. (2012). Providing care for women with gynaecological malignancy: The need for a coordinated national approach. New Zealand Medical Journal, 125(1360). Retrieved from http://www.nzma.org.nz/journal
Kondalsamy-Chennakesavan, S., Yu, C., Kattan, M. W., Leung, Y., Sykes, P., Nascimento, M., … Obermair, A. (2012). Nomograms to predict isolated loco-regional or distant recurrence among women with uterine cancer. Gynecologic Oncology, 125(3), 520-525. doi: 10.1016/j.ygyno.2012.02.022
Evans, G. E., Martínez-Conejero, J. A., Phillipson, G. T. M., Simón, C., McNoe, L. A., Sykes, P. H., … Evans, J. J. (2012). Gene and protein expression signature of endometrial glandular and stromal compartments during the window of implantation. Fertility & Sterility, 97(6), 1365-1373. doi: 10.1016/j.fertnstert.2012.03.007
Evans, J. J., Chitcholtan, K., Dann, J. M., Guilford, P., Harris, G., Lewis, L. K., Nagase, J., … Sykes, P. H. (2012). Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades. Gynecologic Oncology, 125(1), 214-219. doi: 10.1016/j.ygyno.2011.12.429
Journal - Research Other
Walker, N. H., Sabanli, M., Sykes, P. H., Russell, P., & Perez, D. (2012). Successful reproductive outcome following treatment of advanced small cell carcinoma of the ovary. Gynecologic Oncology Reports, 2(3), 115-117. doi: 10.1016/j.gynor.2012.06.001
Sykes, P. H., McAllum, B. E., Simcock, B., & Sadler, L. (2012). [Reply to letter to the editor Initial diagnosis of CIN 2—should patients be managed expectatively?]. American Journal of Obstetrics & Gynecology, 206(3), e11-e12. doi: 10.1016/j.ajog.2011.11.004
Conference Contribution - Published proceedings: Abstract
Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2012). Three-dimensional (3D) micro-environments may provide cell templates for drugs that are different from those of two dimensions (2D). Endocrine Reviews, 33(3, Suppl.), SAT-271. Retrieved from http://press.endocrine.org/series/endo-meetings
Sykes, P., Gopala, K., & Chen, J. (2012). Prevalence and type distribution of human papillomavirus (HPV) in New Zealand women with invasive cervical cancer. International Journal of Gynecological Cancer, 22(8, Suppl. 3), (pp. E767). doi: 10.1097/01.IGC.0000422085.58592.d3
2011
Journal - Research Article
McAllum, B., Sykes, P. H. H., Sadler, L., MacNab, H., Simcock, B. J., & Mekhail, A. K. (2011). Is the treatment of CIN 2 always necessary in women under 25? American Journal of Obstetrics & Gynecology, 205(5), 478.e1-478.e7. doi: 10.1016/j.ajog.2011.06.069
McLeod, M., Cormack, D., Harris, R., Robson, B., Sykes, P., & Crengle, S. (2011). Achieving equitable outcomes for Māori women with cervical cancer in New Zealand: Health provider views. New Zealand Medical Journal, 124(1334). Retrieved from http://journal.nzma.org.nz/journal/124-1334/4661/content.pdf
Obermair, A., Mileshkin, L., Bolz, K., Kondalsamy-Chennakesavan, S., Cheuk, R., Vasey, P., … Sykes, P., & Janda, M. (2011). Prospective, non-randomized phase 2 clinical trial of carboplatin plus paclitaxel with sequential radical pelvic radiotherapy for uterine papillary serous carcinoma. Gynecologic Oncology, 120(2), 179-184. doi: 10.1016/j.ygyno.2010.10.039
Conference Contribution - Published proceedings: Abstract
Flanagan, L., Sykes, P., Miller, A., & Hibma, M. (2011). Antigen presenting cells in the human papillomavirus-induced tumour microenvironment. New Zealand Medical Journal, 124(1346). Retrieved from http://journal.nzma.org.nz/journal/124-1346/4980/content.pdf
Kuiper, C., Molenaar, I. G. M., Dachs, G. U., Currie, M. J., Sykes, P. H., & Vissers, M. C. M. (2011). Low ascorbate levels are associated with high hypoxia-inducible factor-1 activity and a more aggressive tumor phenotype in endometrial cancer. Clinical and Experimental Metastasis. 28(2), (pp. 175). doi: 10.1007/s10585-010-9361-9
Conference Contribution - Verbal presentation and other Conference outputs
Chitcholtan, K., Sykes, P. H., & Evans, J. J. (2011, August). Responses of cancer cells, to doxorubicon and cisplatin, are different in 3D and 2D environments. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.
2010
Journal - Research Article
Janda, M., Gebski, V., Brand, A., Hogg, R., Jobling, T. W., Land, R., … Sykes, P., … Obermair, A. (2010). Quality of life after total laparoscopic hysterectomy versus total abdominal hysterectomy for stage I endometrial cancer (LACE): A randomised trial. Lancet Oncology, 11(8), 772-780. doi: 10.1016/S1470-2045(10)70145-5
Smart, O. C., Sykes, P., McNab, H., & Jennings, L. (2010). Testing for high risk human papilloma virus in the initial follow-up of women treated for high-grade squamous intraepithelial lesions. Australian & New Zealand Journal of Obstetrics & Gynaecology, 50(2), 164-167. doi: 10.1111/j.1479-828X.2009.01132.x
Kuiper, C., Molenaar, I. G. M., Dachs, G. U., Currie, M. J., Sykes, P. H., & Vissers, M. C. M. (2010). Low ascorbate levels are associated with increased hypoxia-inducible factor-1 activity and an aggressive tumor phenotype in endometrial cancer. Cancer Research, 70(14), 5749-5758. doi: 10.1158/0008-5472.CAN-10-0263
McLeod, M., Harris, R., Purdie, G., Cormack, D., Robson, B., Sykes, P., Crengle, S., Iupati, D., & Walker, N. (2010). Improving survival disparities in cervical cancer between Māori and non-Māori women in New Zealand: A National Retrospective Cohort Study. Australian & New Zealand Journal of Public Health, 34(2), 193-199. doi: 10.1111/j.1753-6405.2010.00506.x
Priest, P., Sadler, L., Sykes, P., Marshall, R., Peters, J., & Crengle, S. (2010). Determinants of inequalities in cervical cancer stage at diagnosis and survival in New Zealand. Cancer Causes & Control, 21, 209-214. doi: 10.1007/s10552-009-9451-7
Conference Contribution - Published proceedings: Abstract
Chitcholtan, K., Evans, J., & Sykes, P. H. (2010). Multicellular spheroids of epithelial endometrial cancer: Characterisation and application for anti-cancer drug screening. Proceedings of the International Gynecologic Cancer Society (IGCS) 13th Biennial Meeting. Retrieved from http://www.igcs.org/index.html
Obermair, A., Gebski, V., Nicklin, J., Perrin, L., Jobling, T., Manolitsas, T., … Sykes, P., … Janda, M. (2010). The laparoscopic approach to carcinoma of the endometrium (LACE) randomized trial: Adverse events comparing total laparoscopic hysterectomy versus total abdominal hysterectomy. International Journal of Gynecological Cancer, 20(Suppl. 2). Retrieved from http://journals.lww.com/ijgc/Documents/IGCS%2013%20Meeting%20Abstracts,%20Prague.pdf
2009
Journal - Research Article
Su, H. Y., & Sykes, P. H. (2009). Waiting times for gynaecological cancer surgery. New Zealand Medical Journal, 122(1305). Retrieved from http://journal.nzma.org.nz/journal/122-1305/3854/content.pdf
Dann, J. M., Sykes, P. H., Mason, D. R., & Evans, J. J. (2009). Regulation of Vascular Endothelial Growth Factor in endometrial tumour cells by resveratrol and EGCG. Gynecologic Oncology, 113(3), 374-378.
Journal - Research Other
Sykes, P., Miller, A., & Peddie, D. (2009). Unsatisfactory cervical cytology screening specimens are associated with missed cervical dysplasia and cancer [Author's reply]. BJOG, 116(6), 867. doi: 10.1111/j.1471-0528.2009.02114.x
Conference Contribution - Published proceedings: Abstract
Dann, J. M., Sykes, P. H., Mason, D. R., & Evans, J. J. (2009). Resveratrol and (-)-epigallocatechin-3-gallate reduce VEGF secretion from endometrial tumour cells. Reproductive Sciences, 16(3, Suppl.), 284, (pp. 151A). doi: 10.1177/193371912009163s167
Kuiper, C., Molenaar, I., Dachs, G., Currie, M., Sykes, P., & Vissers, M. (2009). Low ascorbate levels in endometrial tumours are associated with high HIF-1 activity and a more aggressive phenotype. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Dann, J., Evans, J., Sykes, P., Vissers, M., & Mason, D. (2009). Food compounds in the regulation of angiogenic factors in endometrial cancer. Proceedings of the ComBio2009 Conference. [CD-ROM] [Abstract]
Kuiper, C., Molenaar, I., Dachs, G., Currie, M., Sykes, P., & Vissers, M. (2009). Low ascorbate levels in endometrial tumours are associated with high HIF-1 activity and a more aggressive phenotype. Free Radical Biology and Medicine. 47(Suppl. 1), (pp. S172-S173). [Abstract]
2008
Journal - Research Article
Sykes, P. H., Harker, D. Y., Miller, A., Whitehead, M., Neal, H., Wells, J. E., & Peddie, D. (2008). A randomised comparison of SurePath liquid-based cytology and conventional smear cytology in a colposcopy clinic setting. BJOG, 115(11), 1375-1381. doi: 10.1111/j.1471-0528.2008.01865.x
Journal - Research Other
Sykes, P., Sadler, L., & Priest, P. (2008). Screening the hard to reach: Improving morbidity and mortality from cervical cancer in New Zealand [Editorial]. New Zealand Medical Journal, 121(1277). Retrieved from http://journal.nzma.org.nz/journal/121-1277/3135/content.pdf
2007
Journal - Research Article
Jones, R. W., Coughlan, E. P., Reid, J. S., Sykes, P., Watson, P. D., & Cook, C. (2007). Human papilloma virus vaccines and their role in cancer prevention. New Zealand Medical Journal, 120(1266). Retrieved from http://journal.nzma.org.nz/journal/120-1266/2829/content.pdf
Journal - Research Other
North, J., Perez, D., Fentiman, G., Sykes, P., Dempster, A., & Pearse, M. (2007). Primary breast cancer of the vulva: Case report and literature review. Australian & New Zealand Journal of Obstetrics & Gynaecology, 47(1), 77-79. doi: 10.1111/j.1479-828X.2006.00685.x
Conference Contribution - Verbal presentation and other Conference outputs
Sykes, P., Evans, J., Nagasaki, J., Fisher, M., McGraine, Y., & Guilford, P. (2007, May). Understanding angiogenesis in endometrial cancer: A path to new therapies. Verbal presentation at the New Zealand Society for Oncology Conference, Dunedin, New Zealand.
2006
Journal - Research Article
Muys, J. J., Alkaisi, M. M., Melville, D. O. S., Nagase, J., Sykes, P., Parguez, G. M., & Evans, J. J. (2006). Cellular transfer and AFM imaging of cancer cells using Bioimprint. Journal of Nanobiotechnology, 4. Retrieved from http://www.jnanobiotechnology.com/content/4/1/1
Watson, A. J., Smith, B. B., Whitehead, M. R., Sykes, P. H., & Frizelle, F. A. (2006). Malignant progression of anal intra-epithelial neoplasia. ANZ Journal of Surgery, 76(8), 715-717.
Journal - Research Other
Vaughan, M., Sykes, P., Johnson, C., Fitzharris, B., on behalf of the New Zealand Gynaecologic Cancer Group. (2006). Improving outcomes in ovarian cancer [Editorial]. New Zealand Medical Journal, 119(1242). Retrieved from http://journal.nzma.org.nz/journal/119-1242/2171/content.pdf
Conference Contribution - Published proceedings: Abstract
Priest, P., Sadler, L., Sykes, P., Crengle, S., Peters, J., & Marshall, R. (2006). Determinants of ethnic inequalities in cervical cancer survival in New Zealand. Australasian Epidemiologist, 13(3), 69. [Abstract]
Conference Contribution - Verbal presentation and other Conference outputs
Sykes, P. (2006, February). Anal intraepithelial neoplasia. Verbal presentation at the International Society for the Study of Vulvo-vaginal Disease: XVIII World Congree, Queenstown, New Zealand.
Evans, J. J., Muys, J. J., Alkaisi, M. M., Sykes, P. H., Nagase, J., Savigny, P., & McGrath, K. (2006, January). The function of biological cells as revealed by atomic force microscopy. Verbal presentation at the Second BioNanoNetwork (BNN) Meeting, Christchurch, New Zealand.
Sykes, P. (2006, September). New Zealand perspectives on HPV. Verbal presentation at the Vision for Vaccines Symposium, Auckland, New Zealand.
2005
Journal - Research Article
Pather, S., Ford, M., Reid, R., & Sykes, P. (2005). Postpartum curettage: An audit of 200 cases. Australian & New Zealand Journal of Obstetrics & Gynaecology, 45, 368-371.
Sykes, P., Jennings, L., Harker, D., & Beynon, K. (2005). Human papilloma virus is detectable by the Hybrid Capture 2 test in cervical smear samples from women over 40 years of age with high-grade squamous intraepithelial lesions. Australian & New Zealand Journal of Obstetrics & Gynaecology, 45, 457-459.
Sykes, P. H., Reddy, J., & Peddie, D. J. (2005). Does regular cervical screening protect women from microinvasive squamous cell carcinoma of the cervix? A retrospective case-control study. BJOG, 112, 807-809.
Sadler, L., & Sykes, P. (2005). How little is known about cervical cancer in pregnancy? [Editorial]. Annals of Oncology, 16, 341-343.
Sykes, P., Harker, D., & Peddie, D. (2005). Findings and outcome of teenage women referred for colposcopy at Christchurch Women's Hospital, New Zealand. New Zealand Medical Journal, 118(1211). Retrieved from http://journal.nzma.org.nz/journal/118-1211/1350/content.pdf
Conference Contribution - Published proceedings: Abstract
Sykes, P. (2005). Colposcopy and treatment for young women under the age of 20. Proceedings of the Australian Society for Colposcopy and Cervical Pathology 19th Scientific Meeting. [Abstract]
2004
Journal - Research Article
Jones, S., Sykes, P., Pather, S., & Peddie, D. (2004). Is there a role for colposcopy in the follow-up of treated low grade squamous intraepithelial lesions? Australian & New Zealand Journal of Obstetrics & Gynaecology, 44, 574-576.
Losco, G., Sykes, P., Anderson, N., Roberts, H., Fulton, J., & Fraser, H. (2004). Clinical utility of magnetic resonance imaging and the preoperative identification of low risk endometrial cancer. Australian & New Zealand Journal of Obstetrics & Gynaecology, 44(5), 419-422. doi: 10.1111/j.1479-828X.2004.00282.x
Abbas, M. M., Evans, J. J., Sykes, P. H., & Benny, P. S. (2004). Modulation of vascular endothelial growth factor and thymidine phosphorylase in normal human endometrial stromal cells. Fertility & Sterility, 82(Suppl. 3), 1048-1053.
2003
Journal - Research Article
Sykes, P., Allen, D., Cohen, C., Scurry, J., & Yeo, D. (2003). Does the density of lymphatic vascular space invasion affect the prognosis of stage Ib and IIA node negative carcinoma of the cervix? International Journal of Gynecological Cancer, 13, 313-316.
Conference Contribution - Published proceedings: Abstract
Sykes, P. (2003). Does cervical screening prevent microinvasive cancer of the cervix? Proceedings of the Australian Society of Colposcopy and Cervical Pthology XVIIIth Scientific Meeting. [Abstract]
2002
Journal - Research Article
Sykes, P., Nam, S., Wynne, C. J., Anderson, N., North, C. J., Hunter, L., … Fentiman, G. S. (2002). The pre-operative identification of low-risk endometrial cancer: An audit of women treated in the South Island of New Zealand 1998-2000. Australian & New Zealand Journal of Obstetrics & Gynaecology, 42(4), 387-390.
Frizelle, F. A., Beasley, S. W., Roake, J. A., & Sykes, P. (2002). Specialisation within the specialty of general surgery; can the potential advantages be realised? New Zealand Medical Journal, 115, 295-298.
Smith, N., Sykes, P., Frizelle, F. A., & McCormick, P. (2002). High-grade vulval intraepithelial neoplasia (VIN3): A retrospective outcome and relationship to squamous cell carcinoma of the vulva 1989-1999. Australian & New Zealand Journal of Obstetrics & Gynaecology, 42, 67-74.
2001
Journal - Research Article
Pather, S., Sykes, P. H., Davis, R., Reid, R. A., & Skjellerup, N. R. (2001). Thromboprophylaxis following caesarean section; hospital protocols are necessary. New Zealand Medical Journal, 114, 339-340.
Simcock, B., Sykes, P. H., & Laney, M. G. (2001). The impact of the National Cervical Screening Programme on the presentation of cancer of the cervix in Canterbury. New Zealand Medical Journal, 114, 378-380.
1999
Journal - Research Article
Foate, J., Begg, E. J., Anderson, T. J., Bagshaw, P. F., Coulter, G., George, P. M., Macleod, S., … Sykes, P. (1999). The Stent report one year on. New Zealand Medical Journal, 112, 278-279.
1998
Journal - Research Article
Sykes, P., & Mulvaney, P. H. (1998). Mesothelial cell hyperplasia in laparoscopy sites may cause difficulties in the diagnosis, staging, and management of ovarian tumours: a case report. International Journal of Gynecological Cancer, 8, 345-348.
Journal - Research Other
Sykes, P. H., & Mulvany, N. J. (1998). Mesothelial cell hyperplasia in laparoscopy sites may cause difficulties in the diagnosis, staging and management of ovarian tumours: A case report. International Journal of Gynecological Cancer, 8, 345-348.
Black, K., Sykes, P., & Östör, A. G. (1998). Trophoblastic differentiation in an endometrial carcinoma [Case report]. Australian & New Zealand Journal of Obstetrics & Gynaecology, 38(4), 472-473. doi: 10.1111/j.1479-828X.1998.tb03116.x
1997
Journal - Research Article
Sykes, P., Quinn, M. A., & Rome, R. (1997). Ovarian tumours of low malignant potential: A retrospective study of 234 patients. International Journal of Gynecological Cancer, 7, 218-226.
Mulvany, N. J., & Sykes, P. (1997). Desmoplastic melanoma of the vulva. Pathology, 29(2), 241-245. doi: 10.1080/00313029700169974