Jacqueline I Keenan, Alan Aitchison, Frank A Frizelle, Barry D Hock Detection of Chitinase 3-like 1 in Symptomatic Primary Care Patient Faecal Samples Is Not a Reliable Biomarker of Colonic Lesions. Asian Pacific Journal of Cancer Prevention, 2023, 24(7):2289-2293
Arielle Kae Sulit, Michelle Daigneault, Emma Allen-Vercoe, Olin Silander, Barry Hock, Judith McKenzie, John Pearson, Frank Frizelle, Sebastian Schmeier, and Rachel Purcell. Bacterial lipopolysaccharide modulates immune response in the colorectal tumor microenvironment. npj Biofilms and Microbiomes, 2023, Published 23 August
Barry D. Hock, Liping Goddard, Sean A. MacPherson, Matthew Strother, David Gibbs, John F. Pearson, Judith L. McKenzie. Levels and in vitro functional effects of circulating anti-hinge antibodies in melanoma patients receiving the immune checkpoint inhibitor pembrolizumab. PLOS ONE, 2023, Published September 15. https://doi.org/10.1371/journal.pone.0290793
Paula E. Keating, Barry D. Hock, Stewart M. Smith, Paul K. L. Chin, John L. O'Donnell, Murray L. Barclay. Four-year review of New Zealand laboratory infliximab and adalimumab concentration results indicating potential for improved dosing. Internal Medicine Journal, 23 November 2023 https://doi.org/10.1111/imj.16264
2022
Nooshin Ghodsian, Anthony Yeandle, Barry D. Hock and Steven P.Gieseg. CD36 down regulation by the macrophage antioxidant 7,8-dihydroneopterin through modulation of PPAR-γ activity. Free Radic Res. 2022 (5-6):366-367
2021
Keating, Paula; O'Donnell, John; Hock, Barry. Accurate Measurement of Adalimumab Using Competitive Homogeneous Mobility Shift Assay. Therapeutic Drug Monitoring, 2021, 43(1):140-141.
Linda A. Buss, Barry Hock, Troy L. Merry, Abel D. Ang, Bridget A. Robinson, Margaret J. Currie, Gabi U. Dachs. Effect of immune modulation on the skeletal muscle mitochondrial exercise response: An exploratory study in mice with cancer. PLOS ONE. 2021, 16(10): e0258831
Linda A. Buss, Thomas Williams, Barry Hock, Abel D. Ang, Bridget A. Robinson, Margaret J. Currie, Gabi U. Dachs. Effects of exercise and anti-PD-1 on the tumour microenvironment. Immunology Letters. 2021, 239:60-71
Smith-Diaz CC, Magon NJ, McKenzie JL, Hampton MB, Vissers MCM and Das AB. Ascorbate Inhibits Proliferation and Promotes Myeloid Differentiation in TP53-Mutant Leukemia. Front. Oncol. 2021. 11:709543. doi: 10.3389/fonc.2021.709543
Buss LA, Dachs GU, Goddard L, Ang AD, Robinson BA, Currie MJ, Hock B. Is the immunogenicity of PD-1 blocking antibodies a confounding variable in murine studies? Immunol Lett. 2021 Apr 8;234:13-15. doi: 10.1016/j.imlet.2021.04.003. Online ahead of print.
2020
Buss LA, Ang AD, Hock B, Robinson BA, Currie MJ, Dachs GU. Effect of post-implant exercise on tumour growth rate, perfusion and hypoxia in mice. PLoS One. 2020 Mar 18;15(3):e0229290. doi: 10.1371
Baxter-Parker G, Prebble HM, Cross S, Steyn N, Shchepetkina A, Hock BD, Cousins A, Gieseg SP . Neopterin formation through radical scavenging of superoxide by the macrophage synthesised antioxidant 7,8-dihydroneopterin. Free Radic Biol Med. 2020 May 20;152:142-151. doi: 10.1016 5.PMID: 32145301
Keating PE, Duncan R, Spellerberg M, O'Donnell J, Hock BD. Measurement of anti-natalizumab antibodies by homogeneous mobility shift assay. Pathology. 2020 Apr;52(3):373-374. doi: 10.1016
Barry D. Hock, Judith L. McKenzie, Matthew Strother, Liping Goddard, Leah Butt and Margaret J. Currie. Functional effects of immune complexes formed between pembrolizumab and patient-generated anti-drug antibodies. Cancer Immunology, Immunotherapy. 2020, Accepted for publication 9 June 2020.
2019
Jeffry S. Tang, Stephanie M. Bozonet, Judith L. McKenzie, Robert F. Anderson, Laurence D. Melton, and Margreet C. M. Vissers. Physiological Concentrations of Blueberry-Derived Phenolic Acids Reduce Monocyte Adhesion to Human Endothelial Cells. Mol. Nutr. Food Res. 2019, 63, 1900478
Barry D. Hock, Stewart M. Smith, Christopher J. McEntyre, Judith L. McKenzie, Christiaan Sies, Paula E. Keating. Development of a competitive binding homogeneous mobility shift assay for the quantification of adalimumab levels in patient serum. Journal of Immunological Methods. Accepted for publication 12 September 2019.
Purcell RV, Hock BD, Gardner J, Goddard L, MacPherson SA, McKenzie JL. Analysis of human papillomavirus infection and leukaemic infiltrate in cutaneous squamous cell carcinoma from patients with chronic lymphocytic leukaemia. Br J Haematol. 2019 Apr 1. doi: 10.1111/bjh.15907. [Epub ahead of print]
2018
Hock BD, Mulholland KS, Ganly P, McKenzie JL, Pearson JF, MacPherson SA. Impact of increased access to novel agents on the survival of multiple myeloma patients treated at a single New Zealand centre. Intern Med J. 2018, epublished ahead of print, Nov 8.
Barclay ML, Karim S, Helms ETJ, Keating PE, Hock B, Stamp LK, Schultz M. Infliximab and adalimumab concentrations and anti-drug antibodies in inflammatory bowel disease control using New Zealand assays. Intern Med J. 2018 Aug 8
Prebble H, Cross S, Marks E, Healy J, Searle E, Aamir R, Butler A, Roake J, Hock B, Anderson N, Gieseg S. Induced macrophage activation in live excised atherosclerotic plaque. Immunobiology 223 (2018) 526–535
Hock BD, McKenzie JL, Goddard L, Smith SM, McEntyre CJ, Keating PE. Discrimination of anti-drug antibodies with neutralizing capacity in infliximab and adalimumab treated patients: Comparison of the homogeneous mobility shift assay and the affinity capture and elution assay. Therapeutic Drug Monitoring. 2018; 40: 705-715
A.W. Greer, J.L. McKenzie, R.W. McAnulty, J.F. Huntley, T.N. McNeilly. Immune development and performance characteristics of Romney sheep selected for either resistance or resilience to gastrointestinal nematodes. Veterinary Parasitology 250 (2018) 60-67.
2017
Shchepetkina, AA., Hock, BD., Miller, A., Kennedy, MA., Gieseg, SP., Effect of 7,8-dihydroneopterin mediated CD36 down regulation and oxidant scavenging on oxidised low-density lipoprotein induced cell death in human macrophages. International Journal of Biochemistry and Cell Biology http://dx.doi.org/10.1016/j.biocel.2017.03.017
Hock BD, McKenzie JL, Keenan JI. Helicobacter pylori outer membrane vesicles inhibit human T cell responses via induction of monocyte COX-2 expression. Pathogens and Disease. 2017; in press.
Hock BD, MacPherson SA, McKenzie JL. Idelalisib and caffeine reduce suppression of T cell responses mediated by activated chronic lymphocytic leukemia cells. PLoS ONE. 2017, 12(3): e0172858.
2016
Hock BD, McIntosh ND, McKenzie JL, Pearson JF, Simcock JW, MacPherson SA. Incidence of cutaneous squamous cell carcinoma in a New Zealand population of Chronic Lymphocytic Leukaemia patients. Intern Med J. 2016 Dec;46(12):1414-1421.
Seddon A, Hock B, Miller A, Frei L, Pearson J, McKenzie J, Simcock J, Currie M. Cutaneous squamous cell carcinomas with markers of increased metastatic risk are associated with elevated numbers of neutrophils and/or granulocytic myeloid derived suppressor cells. J Dermatol Sci. 2016 Apr 26 epublished ahead of print.
Hock BD, Stamp LK, Hayman MW, Keating PE, Helms ET, Barclay ML. Development of an ELISA based competitive binding assay for the analysis of drug concentration and anti-drug antibody levels in patients receiving adalimumab or infliximab. Therapeutic Drug Monitoring, 2016,38:32-41
2015
Hock BD, McKenzie JL, Cross NB and Currie MJ. Dynamic changes in myeloid derived suppressor cell subsets following renal transplant: A prospective study. Transplant Immunology, 2015, 32 (3):164-171.
2014
Hock BD, Macpherson SA, Fernyhough LJ and McKenzie JL. Chronic Lymphocytic Leukemia Cells become both activated and immunosuppressive following interaction with CD3 and CD28 stimulated PBMC. Leukemia Research, 2014, 38(10):1217-23.
2013
Hock BD, McKenzie JL. Suppression of CD3/CD28 antibody stimulated responses by human granulocytic myeloid-derived suppressor cells: Fact or artefact? Immunol Lett. 2013 May;152(2):151-2
Barry D. Hock, Liam J. Fernyhough, Sheryl M. Gough, Judith L. McKenzie. Clinical Significance of Plasma Levels of Soluble CD40 in Patients with Chronic Lymphocytic Leukemia. Open Journal of Blood Diseases, 2013, 3, 1-5
Fernyhough, L.J., Buchan, V.A., McArthur, L.T., and Hock, B.D. Relative recovery of haematopoietic stem cell products after cryogenic storage of up to 19 years. Bone Marrow Transplantation. 2013; 48(1):32-35
Fernyhough, L.J., Hock, B.D., Taylor, J., Pearson, J., and Ganly, P. Survival of myeloma patients following the introduction of thalidomide as a second line therapy: a retrospective study at a single New Zealand centre. Internal Medicine Journal. 2013;43(2):130-137
2012
Hock BD, Taylor KG, Cross NB, Kettle AJ, Hampton, MB and McKenzie JL. Effect of activated human polymorphonuclear leucocytes on T lymphocyte proliferation and viability. Immunology. 2012; 137, 249-258.
Mottram PL, McKenzie IFC, McKenzie JL. A History of Experimental Small Animal Transplants in Australia : a personal perspective. In: Tait BD ed.More Than a Footnote : The Story of Organ Transplantation in Australia and New Zealand; 2012:449-464.
Hock BD, Mackenzie KA, Cross NB, Taylor KG, Currie MJ, Robinson BA, Simcock JW and McKenzie JL. Renal transplant recipients have elevated frequencies of circulating myeloid-derived suppressor cells. Nephrol Dial Transplant. 2012; 27(1):402-10.
2011
Mackenzie KA, Miller AP, Hock BD, Gardner J, Simcock JW, Roake JA, Dachs GU, Robinson BA, Currie MJ. Angiogenesis and host immune response contribute to the aggressive character of non-melanoma skin cancers in renal transplant recipients. Histopathology. 2011; 58:875-85. Epub date 2011/05/19.
Glubb, D. M., Gearry, R. B., Barclay, M. L., Roberts, R. L., Pearson, J., Keenan, J. I., McKenzie, J and Bentley, R. W. NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease. World Journal of Gastroenterology. 2011; 17(23), 2829-2837.
2010
Hock BD, McKenzie JL, McArthur L, Tansley S, Taylor KG and Fernyhough LJ. Analysis of CD38 expression as a prognostic marker in chronic lymphocytic leukemia patients in a single New Zealand Centre. Intern Med J. 2010 Dec;40(12):842-9
2009
Hock BD, Fernyhough LJ, Gough SM, Steinkasserer A, Cox AG and McKenzie JL. Release and clinical significance of soluble CD83 in chronic lymphocytic leukemia. Leukemia Research. 2009; 33:1089-1095.
2008
Geertsema L, Lucas S, Cotter J, Hock B, McKenzie J and Fernyhough L. The cardiovascular risk factor, soluble CD40 ligand (CD154), but not soluble CD40, is lowered by ultra-endurance exercise in humans. British Journal of Sports Medicine. 2008; published online 26 August.
Saunderson SC, Schuberth PC, Dunn AC, Miller L, Hock BD, MacKay PA, Koch N, Jack RW and McLellan AD. Induction of Exosome Release in Primary B Cells Stimulated via CD40 and the IL-4 Receptor. Journal of Immunology. 2008; 180:8146-8152
2007
Lundell AC, Adlerberth I, Lindberg E, Hock B et al. Increased levels of circulating soluble CD14 but not CD83 in infants are associated with early intestinal colonization with Staphylococcus aureus. Clinical and Experimental Allergy. 2007;37:62-71.
2006
Zinser E, Lechmann M, Golka A, Hock B, Steinkasserer A. Determination of the inhibitory activity and biological half-live of soluble CD83: comparison of wild type and mutant isoforms. Immunobiology. 2006;211:449-453.
Hock B, McKenzie J, Patton WN, Drayson M, Taylor K, Wakeman C, Kantarjian H, Giles F and Albitar M. Circulating levels and clinical significance of soluble CD40 in patients with haematological malignancies. Cancer; 2006;106:2148-2157.
Hock BD, Drayson M, Patton WN, Taylor K, Kerr L, and McKenzie JL. Circulating levels and clinical signifance of soluble CD86 in myeloma patients. British Journal of Haematology; 2006;133:165-172.
Hock B, O'Donnell J, Taylor K, Steinkasserer A, McKenzie J, Rothwell A and Summers K. Levels of the soluble forms of CD80, CD86 and CD83 are elevated in the synovial fluid of rheumatoid arthritis patients. Tissue Antigens; 2006; 67:57-60
Jarvis MD, Rademaker MT, Ellmers LJ, Currie MJ, McKenzie JL, Palmer BR, Frampton CM and Cameron VA. Comparison of infarct-derived and control ovine cardiac myofibroblasts in culture: Response to cytokines and natriuretic peptide receptor expression profiles. American Journal of Physiology. 2006; 291:H1952-H1958
2005
Hock BD, Roberts G, McKenzie JL, Gokhale P, Salm N, McClellan A, Patton WN, Roake JA. Exposure To The Electrofusion Process Can Increase The Immunogenicity Of Human Cells. Cancer Immunology And Immunotherapy, 2005; 54: 880-890.
2004
Hock BD, Starling GC, Patton WN, Salm N, Bond K, McArthur LT and McKenzie JL. Identification of a circulating soluble form of CD80: Levels in patients with hematological malignancies. Leukemia & Lymphoma, 2004; 45: 2111-2118.
Hock BD, Haring LF, Steinkasserer A, Taylor KG, Patton WN and McKenzie JL. The soluble form of CD83 is present at elevated levels in a number of hematological malignancies. Leukemia Research 2004; 28 : 237 241
2003
Hock BD, McKenzie JL, Patton WN, Haring LF, Yang Y, Shen S, Estey EH and Albitar M. Clinical significance of soluble CD86 levels in acute myeloid leukemia and myelodysplastic syndrome. Cancer 2003; 98 :1681 - 1688
Copland MJ, Baird MA, Rades T, McKenzie JL, Becker B, Reck F, Tyler P and Davies NM. "Liposomal delivery of antigen to human dendritic cells." Vaccine 21: 883, 2003
2002
Hock BD, Haring LF, Ebbert AM, Patton WN, McKenzie JL "Differential effects of G-CSF momobilisation on dendritic cell subsets in normal allogeneic donors and patients undergoing autologous transplantation" Bone Marrow Transplantation 30:773, 2002
Hock BD, Patton WN, Budhia S, Mannari D, Robert P and McKenzie JL . Human plasma contains a soluble form of CD86 which is present at elevated levels in some leukemia patients. Leukaemia 16: 865, 2002
Kennedy-Smith AG, McKenzie JL, Owen MC, Davidson PJT, Vuckovic S and Hart DNJ. Prostate specific antigen inhibits immune responses in vitro: a potential role in prostate cancer. Journal of Urology 168:741,2002 August 2002
Hock, B.D., Kato, M., McKenzie, J.L. and Hart, D.N.J. A soluble form of CD83 is released from activated dendritic cells and B lymphocytes, and is detectable in normal human sera. International Immunology 13:959-967, 2002
2001
Summers, K.L., Hock, B.D., McKenzie, J.L. and Hart, D.N.J. Phenotypic characterization of five dendritic cell subsets in human tonsils. American Journal of Pathology 159:285-295, 2001
2000
Sherbini H, Hock BD, Fearnley D, McLellan A, Vuckovic S, Hart DNJ. Lectin ligands on human dendritic cells and identification of a peanut agglutinin positive subset in blood. Cellular Immunology 200: 36, 2000
Kato M, Neil TK, Fearnley DB, McLellan AD, Vuckovic S, and Hart DN: Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells International Immunology 12: 1511, 2000
1999
Hock BD, Fearnley DB, Boyce A, McLellan AD, Sorg RV, Summers KL, Hart DNJ. Human Dendritic cells express a 95 kDa activation/differentiation antigen defined by CMRF-56. Tissue Antigens 53: 320-34, 1999
McLellan AD, Heiser A, and Hart DNJ: Induction of dendritic cell costimulator molecule expression is suppressed by T cells in the absence of antigen specific signalling: role of cluster formation, CD40 and HLA-class II for dendritic cell activation. Immunology 98: 171, 1999
1998
McLellan AD, Sorg RV, Heiser A, Fearnley DB, Hart DNJ: Dendritic cells in the T cell areas of normal human skin display an activated phenotype. Journal of Investigative Dermatology. 111(5): 841, 1998
Mannering SI, McKenzie JL and Hart DNJ. Optimization of the conditions for generating human DC initiated antigen specific T lymphocyte lines in vitro. Journal of .Immunological Methods 219 1: 69, 1998
