Details
- Close date
- Thursday, 30 November 2023
- Academic background
- Health Sciences
- Host campus
- Dunedin
- Qualifications
- Master's, PhD
- Department
- Pathology (Dunedin)
- Supervisor
- Dr Adele Woolley
Overview
Osteoarthritis (OA) is a debilitating disease which is projected to affect increasing numbers of our aging population, posing an ongoing and significant health and economic burden to New Zealand.
OA is the most common form of arthritis and is traditionally associated with mechanical 'wear and tear'. There are limited therapeutic options available, resulting in prolonged disability and decreased quality of life, until the advent of end stage joint replacement. Recent research has found that patients may suffer from different types of OA which are due to a variety of factors including some which are driven by inflammation.
This proposal aims to identify inflammatory biomarkers in patients with this inflammatory subtype which will lead to both early intervention and to greatly improved health outcomes.
This project uses immunofluorescence to label specific proteins in patient tissue before imaging using microscopy. It also involves the use of RNAScope to label specific transcripts within the cells
Useful information
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