Investigation of genetic and epigenetic signatures of primary and metastatic cancer (melanoma and colorectal cancer)

Details

Close date

No date set

Academic background

Health Sciences, Sciences

Host campus

Dunedin

Qualification

Postgraduate Certificate, Postgraduate Diploma, Master's, PhD, Honours

Department

Pathology (Dunedin)

Supervisor

Associate Professor Aniruddha Chatterjee, Dr Euan Rodger

Overview

If you would like to join our lab to perform cutting edge research while collaborating with top clinicians in New Zealand and internationally, please enquire to find out more.

The aim of this theme is to identify progressive epigenetic changes responsible for or involved in cancer metastasis. There is substantial interest in developing methylation-based biomarkers (as these are DNA based, they are stable and easily measurable). Further, unlike genetic changes, epigenetic changes are reversible and the growing efforts to develop combinatorial therapies (e.g. immunotherapy with epigenetic therapies) are already showing promising results. Improved understanding of functional epigenetic changes would significantly contribute to develop early cancer detection strategies and new epigenetic therapies to enhance patient outcomes.

Useful information

• Graduate research at the University of Otago
• Scholarships at the University of Otago

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