Paumann-Page M, Tscheliessnig R, Sevcnikar B, Katz RS, Schwartz I, Hofbauer S, Pfanzagl V, Furtmüller PG, Obinger C. Monomeric and homotrimeric solution structures of truncated human peroxidasin 1 variants. Biochim Biophys Acta Proteins Proteom. 2020 Jan;1868(1):140249. doi: 10.1016/j.bbapap.2019.07.002. Epub 2019 Jul 8. PMID: 31295557
Zawari M., Poller B., Walker G.F., Pearson A.G., Hampton M.B. and Carr A.C. Formulation of broccoli sprout powder in gastro-resistant capsules protects against the acidic pH of the stomach in vitro, but does not increase isothiocyanate bioavailability in vivo. Antioxidants in press, 2019.
Rani Talla U., Bozonet S.N., Parker H.A., Hampton M.B. and Vissers M.C.M. Prolonged exposure to hypoxia induces an autophagy-like cell survival program in human neutrophils. J Leukocyte Biology. in press
Dickerhof N, Isles V, Pattemore P, Hampton MB, Kettle AJ. Exposure of Pseudomonas aeruginosa to bactericidal hypochlorous acid during neutrophil phagocytosis is compromised in cystic fibrosis. JBC, In press, Available online doi: 10.1074/jbc.RA119.009934
Dagnell M, Cheng Q, Rizvi SHM, Pace PE, Boivin B, Winterbourn CC, Arnér ESJ. Bicarbonate is essential for protein tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades. J Biol Chem. 2019 Jun 13. pii: jbc.RA119.009001. doi: 10.1074/jbc.RA119.009001. [Epub ahead of print]
Bozonet SM, Carr AC. The Role of Physiological Vitamin C Concentrations on Key Functions of Neutrophils Isolated from Healthy Individuals. Nutrients 2019, 11(6), 1363; https://doi.org/10.3390/nu11061363 This will be published in the special issue: Vitamin C: From Bench to Bedside
Tang JS, Bozonet SM, McKenzie JL, Anderson RF, Melton LD, Vissers MCM. Physiological concentrations of blueberry-derived phenolic acids reduce monocyte adhesion to human endothelial cells. Molecular Nutrition & Food Research (Impact Factor 2017 - 5.15).
Cheng D, Talib J, Stanley CP, Rashid I, Michaëlsson E, Lindstedt E, Croft KD, Kettle AJ, Maghzal GJ, Stocker R. Inhibition of MPO (Myeloperoxidase) Attenuates Endothelial Dysfunction in Mouse Models of Vascular Inflammation and Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology. May 2019
Hoskin T, Crowther JM, Cheung J, Epton MJ, Sly PD, Elder PA, Dobson RCJ, Kettle AJ, Dickerhof N. Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis. Redox Biology, In print
Campbell EJ, Dachs GU, Morrin H, Davey V, Robinson BA, Vissers MCM. Activation of the hypoxia pathway in breast cancer tissue and patient survival are inversely associated with tumor ascorbate levels. BMC Cancer; In press, (2019)
Wohlrab C, Kuiper C, Vissers MCM, Phillips E, Robinson BA, Dachs GU. Ascorbate modulates the hypoxic pathway in renal cell carcinoma cells by increasing intracellular activity of the HIF hydroxylases in renal cell carcinoma cells. Hypoxia; In press (2019)
de Souza LF, Pearson AG, Pace PE, Dafre AL, Meotti FC, Hampton MB, Winterbourn CC. Peroxiredoxin expression and redox status in neutrophils and HL-60 cells. in press Free Radical Biology and Medicine.
2018
Winterbourn CC. Regulation of intracellular glutathione, Redox Biology, available online 26 December 2018
Wilson R, Willis J, Gearry R, Hughes A, Lawley B, Skidmore P, Frampton C, Fleming E, Anderson A, Jones L, Tannock G, Carr A. SunGold kiwifruit supplementation of individuals with prediabetes alters gut microbiota and improves vitamin C status, anthropometric and clinical markers. Nutrients, 2018, in press.
Foster M, Carr A, Antony A, Peng S, Fitzpatrick M. Intravenous vitamin C administration improved blood cell counts and health-related quality of life of patient with history of relapsed acute myeloid leukaemia. Antioxidants, 2018, in press.
Pullar J, Carr A, Bozonet S, Vissers M. High vitamin C status is associated with elevated mood in male tertiary students. Antioxidants, 2018, in press.
Prier M, Carr A, Baillie N. No reported renal stones with intravenous vitamin C administration: A prospective case series study. Antioxidants, 2018, in press.
Bathish B, Turner R, Paumann-Page M, Kettle AJ, Winterbourn CC. Characterisation of peroxidasin activity in isolated extracellular matrix and direct detection of hypobromous acid formation. Archives of Biochemistry and Biophysics, 4 Apr 2018
Pullar JM, Bayer S, Carr AC. Appropriate Handling, Processing and Analysis of Blood Samples is Essential to Avoid Oxidation of Vitamin C to Dehydroascorbic Acid. 2018, Antioxidants, in Press.
Khalilova IS, Dickerhof N, Mocatta TJ, Bhagra CJ, McClean DR, Obinger C, Kettle AJ. A myeloperoxidase precursor, pro-myeloperoxidase, is present in human plasma and elevated in cardiovascular disease patients. PLOS ONE
Forbes LV, Kettle AJ. A multi-substrate assay for finding physiologically effective inhibitors of myeloperoxidase. Analytical Biochemistry 544 (2018)
Tang, J. S., Vissers, M. C. M., Anderson, R. F., Sreebhavan, S., Bozonet, Stephanie. M., Scheepens, A. and Melton, L. D. Bioavailable Blueberry-Derived Phenolic Acids at Physiological Concentrations Enhance Nrf2-Regulated Antioxidant Responses in Human Vascular Endothelial Cells. Mol. Nutr. Food Res., Accepted Manuscript.
Coker MS, Forbes LV, Plowman-Holmes M, Murdoch DR, Winterbourn CC, Kettle AJ. Interactions of staphyloxanthin and enterobactin with myeloperoxidase and reactive chlorine species. Archives of Biochemistry and Biophysics 646 (2018) 80-89
A Carr, C Wohlrab, P Young, R Bellomo. Stability of intravenous vitamin C solutions: a technical report, Critical Care & Resuscitation, 2018, in press.
Hampton MB, Vick KA, Skoko JJ, Neumann CA. Peroxiredoxin Involvement in the Initiation and Progression of Human Cancer. Antioxid Redox Signal. 2018 Mar 1;28(7):591-608. doi: 10.1089/ars.2017.7422. Epub 2018 Feb 1.
Yewdall NA, Peskin A, Hampton MB, Goldstone D, Pearce FG, Gerrard JA. Quaternary structure influences the peroxidase activity of peroxiredoxin 3. Biochem Biophys Res Commun. 2018 Feb 10.
Winterbourn CC1. Biological Production, Detection, and Fate of Hydrogen Peroxide. Antioxid Redox Signal. 2017 Dec 14. doi: 10.1089/ars.2017.7425. [Epub ahead of print]
Schindler L, Dickerhof N, Hampton MB, Bernhagen J. Post-translational regulation of macrophage migration inhibitory factor: Basis for functional fine-tuning. Redox Biology (15) 135-142, 2018
Das, A. B., Sadowska-Bartosz, I., Königstorfer, A., Kettle, A. J., Winterbourn C. C. (2018). Superoxide dismutase protects ribonucleotide reductase from inactivation in yeast. Free Radical Biology & Medicine, 116, 114-122. doi: 10.1016/j.freeradbiomed.2018.01.001
Vissers, M. C. M., & Das, A. B. Potential Mechanisms of Action for Vitamin C in Cancer: Reviewing the Evidence. Frontiers in Physiology, 9, 809,(2018). https://doi.org/10.3389/fphys.2018.00809