The sequencing of the human genome in 2001 initiated a decade of rapid advance in understanding the impact of genetic variation in the human genome on human disease.
This, and the advent of new 'next generation sequencing' technologies that enables identification of all variation in individual genomes, ensures that genetic approaches to human diseases will continue to be prominent in health research.
Conducting Māori and Pacific-focused research requires consultation and on-going engagement with specific communities and organisations, to initiating and conducting the research consistent with cultural values and protocols, as well as dissemination and translation.
This represents unique challenges including appropriate processes needed to facilitate genomic scientists to fulfil obligations to Māori and Pacific communities and assist their engagement with these communities. The growth of Māori and Pacific capability in genetics is required.
The focus of this theme will be on strengthening research with Māori and Pacific communities (in New Zealand and the South Pacific) on genetics of health. This will be achieved by integrating diverse areas of expertise:
- Engagement with communities on initiation of genetic research projects and translation of results
- Increasing Māori and Pacific capability in genetics
- Improved statistical and bioinformatic approaches
- More knowledge about how modern genomes were shaped by migration and environment
