Professor Roslyn Kemp

Immunologist
Member, Ako Aotearoa Academy of Tertiary
Teaching Excellence

BSc(Hons), Otago (1997) PhD, Otago, Malaghan Institute (2001) Post-doctoral Fellow, Trudeau Institute, USA (2002-4) Post-doctoral Fellow, Oxford University, UK (2004-5) Career Development Fellow, National Institute for Medical Research, UK (2005-8); Member of Ako Aotearoa Academy for Tertiary Teaching Excellence

Email roslyn.kemp@otago.ac.nz
Tel +64 3 479 7708

Appointed: 2009

Teaching roles

MICR 334 Advanced Immunology (Convenor)
MICR 331 Food Microbiology
MICR 223 Infection and Immunity
MICR 360 Research Perspectives

Research interests

Applied and molecular immunology, cancer immunobiology, vaccines – immunology and technology

Current research

My research focuses on T cells as mediators of anti-tumour immunity and inflammation. Specifically, we study the role of inflammation and the unique features of different subsets of T cells and myeloid cells, focussing on cancer and gut-specific immune responses; and how these cell subsets are involved in patient outcome. We use high dimensional tools and analyses to study the networks of cells and molecules in the immune response

We are currently looking at T cell and myeloid cell subsets in colorectal cancer and inflammatory bowel disease to improve diagnosis, prognosis and treatment. We are analysing the molecular signalling pathways in T cells.

Research projects

My current areas of research are mucosal and tumour immune responses, inflammation and T cell memory.

Mucosal Immune Responses in Cancer and Inflammatory Diseases

Using immune responses in the tumour to predict patient outcome in colorectal cancer
Investigating T cell responses in inflammatory bowel disease patients
Using human intestinal organoids to model the gut immune response
Heterogeneity and plasticity of T cell subsets in the gut mucosa and their influence on anti-tumour immune responses
Generating gut-specific memory T cells through vaccination
Development of new analytical tools to study high dimensional immune data

CD8+ T Cell Memory

Interactions between naïve and memory T cell populations
Vaccination strategies to generate effective T cell memory populations

Molecular Pathways controlling T cells

Molecular signals controlling memory T cell development and maintenance
Signalling pathways in tumour immune responses

Lab group

Dr Andrew Highton, Kia Niwha Leader Fellow
https://www.teniwha.com/news/kia-niwha-leader-fellowships-announced
Dr Kirsten Ward-Hartstonge, Research Fellow
Dr Safina Gadeock, Research Fellow
Dr Lisa Fan, Research Assistant and Lab Manager

Postgraduate students

Janet Rhodes: PhD student
- 2018 – HRC Clinical Research Fellowship
- 2019 – Gut Cancer Foundation Award
- 2019 – Richard Stewart Fund
- 2019 – AAI Travel for Techniques Award
Doug Gaskarth: PhD student
- 2022 – Sandy Smith Memorial Award
- 2021 – Best poster award, BMS Postgraduate symposium
- 2020 – Cancer Society of NZ PhD Scholarship
Rory Costello: PhD student
- 2023 Australasian Cytometry Society Travel Award
Brad Devery: PhD student
- 2023 Australasian Cytometry Society Travel Award
- 2023 Admitted to ASI Advanced Immunology School
Mikayla King, BSc Hons student
Millie Ro,: BBiomedSc Hons student
Naomi Grambin, BSc Hons student
Josephine Maes, Visiting student

Past lab members

Kaleialoha Nginingini, Intern, 2024
Justin Tirados, BBiomedSc Hons student 2019; PhD student 2020-23. Current position: flow cytometry manager, University of Otago
- 2022 Australasian Cytometry Society Travel Award
Gemma Laws, BBiomedSc Hons student 2014; MSc student 2017-18; PhD student 2020-23. Current position: postdoctoral fellow, Oxford University, UK PhD student
- 2022 – Winner Buck Award - best student presentation NZASI
- 2022 – ASI Travel Award
- 2022 – MPPT Travel Award
- 2022 – AAI Travel for Techniques Award
- 2021 – Best student presentation, BMS Postgraduate symposium
Jessica Harte, BBiomedSc Hons student 2018; PhD student 2019-23. Current position: postdoctoral fellow, Walter and Elisa Hall Institute, Melbourne
- 2022 – Cancer Research Trust Professional Development Award
- 2022 – Australasian Cytometry Society Travel Award
- 2022 – ASI Travel Award
- 2019 – Cancer Society of NZ PhD Scholarship
Moira Heron, BSc Hons student 2021. Current position: University of Otago administration
Ginny Niemi, MSc student 2016-17; lab manager 2017-20. Current position: research technician, Amaroq
Sonya Fenton, BBiomedsci Hons student 2020. Current position: Dunedin Colorectal Cohort Research Fellow
Amy Watts, BBiomedsci Hons student 2020. Current position - High School Teacher, Lumsden
Paulo Urbano, Postdoctoral fellow 2019-2020. Current position: Field Service Engineer- Flow Cyotmetry, Copenhagen
Hamish Angus, BSc Hons student 2016; PhD student 2017-2020. Current position: Teach First NZ Scholar, Whangarei High School
Doug Gaskarth, MSc student 2018 - 2019. Current position: PhD student, Kemp lab
Luis Munoz-Erazo, postdoctoral fellow 2018-2019. Current position: University of Auckland
Sam Norton, BBiomedSci (Hons) student 2013, PhD student 2014 - 2017, postdoctoral fellow 2018-19. Current position: founder, Nanix, www.nanix.co.nz; Bioinformatics Software Engineer, Becton Dickinson
- 2nd place, OSMS Postgraduate Symposium Poster 2016
- Sandy Smith Scholarship 2015
- Genesis Oncology Trust Professional Development Award 2015
- Webster Centre for Infectious Disease Travel Award 2014
- ASI Travel Award 2014
- Gut Health Network Travel Award 2014
- winner OMSRS PhD Award 2014
Simon Shirley, MSc student 2015 (with Sarah Hook); PhD student 2016 - 2019 (with Julie Cakebread and Ali Hodgkinson, AgResearch) . Current position: postdoctoral fellow, Rockefeller University, New York, USA
Julia Leman, MSc student 2017 - 2018. Current position: PhD student, Germany
- 2nd Place BMS Postgraduate Symposium Short Talk 2017
Kit Moloney-Geany, PGDip student 2018. Current position: PhD student, Department of Biochemistry
Kirsten Ward-Harststonge, PGDipSci student 2013, PhD student 2014 - 2017. Current Position: Postdoctoral Fellow, University of Otago.
- Winner NZASI Buck Award Immunology 2017
- Genesis Professional Development Award 2017
- Winner - Young Researcher Award NZ Society of Oncology 2016
- Winner OMSRS PhD Award 2016
- Winner OSMS Postgraduate Symposium PK Talk 2016
- Awarded ASI Travel Award to attend ICI 2016
- Awarded Lotteries Research Health PhD Scholarship 2014
- Awarded Genesis Oncology Trust Post-graduate Scholarship 2014 (declined)
- winner - Brenda Shore Award for Women 2014
- winner - Todd Foundation Award for Excellence 2014
Shirley Shen, MSc student 2015 - 2017. Current Position: Regulatory Affairs and Medical Associate, Pharmaco NZ
- Student Representative Australasian Society of Cytometry
- 2nd Place OSMS Postgraduate Symposium PK Talk 2016
Garrett Chin, BSc (Hons) student 2015. Current Position: Engagement Manager, Hounslow Borough Based Partnership, London, UK
Ed Taylor, BSc (Hons) student 2011; summer student 2010/11; PhD student 2012 - 2016. Current Position: Product @ Kiwibank
- Webster Centre for Infectious Disease Travel Award 2014
- Maurice and Phyllis Paykel Trust Travel Award 2014
- ASI Travel Award 2014
- Gut Health Network Travel Award 2014
- runner up Buck Award for best student presentation NZASI 2014
- awarded Sandy Smith Memorial Scholarship 2013
- awarded ASI Travel Award 2013
- awarded NZASI Travel Award 2013
- winner Eli Lilly Award for best trainee presentation at NZSO 2013
- awarded NZSO Trainee Travel Award 2012
- 1st equal 4th Year student presentation 2011
- Featured in ODT 2013
Andrew Highton, B. Biomed. Sci Hons Student 2010; Ph.D. student 2011 - 2015. Current position: University of Otago
- winner Eli Lilley Award for best trainee presentation at NZSO 2014
- awarded NZSO Travel Grant 2014
- awarded Nuffield Medical Post-doctoral Fellowship to Oxford University 2014
- 1st= poster prize - Australasian Vaccines and Immunotherapeutics Development Meeting 2014
- highly commended (poster) OSMS Postgraduate Research Forum 2014
- awarded Gut Health Network Travel Award 2013
- awarded NZASI Travel Award 2013
- awarded Webster Center for Infectious Disease Travel Scholarship 2013
- winner of the Otago Medical Research Society Prize at the Division of Health Sciences Annual Research Forum 2012
- awarded Sandy Smith Memorial Scholarship 2012
- awarded ASI Travel Award 2010
Tim McCulloch, Research Technician 2014. Current position: PhD Student, Australia.
Tom Worters, BBiomedSci (Hons) Student 2014 (with Grant Butt). Current position: Policy Officer, Department of Premier and Cabinet, Victoria, Australia
- awarded First Class Hons
Elliott Dunn, M.Sc Student 2012 – 2014. Current position: Brandon Capital.
- second place Dept 4th Year Presentations 2012
- awarded second prize at the Otago Medical School Research Society Awards for 4th Year Students 2012
- awarded second prize at the Otago Medical School Research Society Awards for Summer Students 2013
- People's Choice Award - 2013 OSMS Postgrad Symposium
- Winner - Baxter Healthcare Young Investigator Award 2013
- awarded Gut Health Network Travel Award 2013
Kristian Thomson, M.Sc Student (with Michelle McConnell) 2012 – 2014. Awarded NZASI Travel Award 2013. Current position: PhD student, Germany
Georgia Bell, Summer Student 2011-12, PGDip.Sci Student 2012 - 2013. Current position - Kai Putaiao Maori, ESR.
- Research Technician 2012 – 2014
- awarded Rona Scholarship 2014
Adrian Patterson, Summer Student 2012-13. Awarded University of Otago Scholarship in Science. Current position: Medical Writer, BPAC
Adam Girardin, Research Technician: 2009 - 2012. Current position - GP registrar, Melbourne.
- awarded NZSO Trainee Member Travel Award 2011
Cameron Field, B.Sc Hons Student 2011, Research Technician 2012. Current position - Biotech Drug Discovery Program Lead, London, UK.
- awarded Best Student Presentation Award at NZASI 2012
Elyce du Mez, B.Sc Hons Student 2011; Summer Student 2011/12, Research Technician July 2012 - Oct 2012. Current position: Assurity Consulting.
Fabienne Libuda, Visiting M.Sc Student (Hannover Medical School) 2011/12. Current position - PhD student, Hanover, Germany.
Julia Prier, B.Sc Hons Student 2010; Summer Student 2009/10, 2010/11
- awarded ASI Travel Award 2010
- awarded Webster Centre for Infectious Disease Postgraduate Travel Award 2010
- Highly Commended OSMS Summer Studentship 2010/11

Nicola King, Summer Student 2009/10, 2010/11

Other activities

Deputy HOD, Microbiology and Immunology
Member, Ako Aotearoa Academy for Tertiary Teaching Excellence
Council Member, International Union of Immunological Societies
Co-chair IUIS Committees: Publications, Education, Gender Equity
Centre for Translational Cancer Research
New Zealand Society of Oncology
Gut Health Network
Live Human Tissue Network
University of Otago Supervisor of the Year 2013, 2020

Current sources of funding

Health Research Council NZ
Maurice Wilkins Centre
Marsden Fund

Collaborations

T Cell Responses in Colorectal Cancer - Dr Mik Black, Department of Biochemistry, Prof John McCall, Department of Surgical Sciences, Prof Sarah Hook, School of Pharmacy
Immune Scoring in Colorectal Cancer - Prof John McCall, Department of Surgery; Dr Michael Jameson, Waikato DHB, Dr Sharon Pattison, Department of Medicine
Enhancing T Cell Memory with Vaccination - Professor Sarah Hook, School of Pharmacy
Gut Immune Responses in Patients with Inflammatory Disease - Professor Michael Schultz, Department of Medicine, Dr Ella Iosua, Centre for Biostatistics
High Dimensional Analysis of Immune Responses - Dr Helen McGuire, Professor Barbara Fazekas de St Groth, Dr Tom Ashhurst, Dr Felix Marsh-Wakefield; University of Sydney
Immune and Microbial Interactions – Professor Xin Luo, Virginia Tech

Publications

Costello, R. M., Fenton, S., McGuire, H., Lim, L., Howell, D., Raza, Q., … Kemp, R. (2024). Predicting colorectal patient prognoses by functional characterisation of heterogeneous cell types and their spatial interaction using a new technique: Whole slide imaging mass cytometry. Cancer Research, 84(6, Suppl.), 67. doi: 10.1158/1538-7445.AM2024-67 Conference Contribution - Published proceedings: Abstract

Kemp, R. A., & Brown, D. M. (2024). How to be a scientist: Critical thinking in the life sciences. Boca Raton, FL: CRC Press, 252p. doi: 10.1201/9781003326366 Authored Book - Research

Norton, S. E., Khong, T., Ramachandran, M., Highton, A. J., Ward-Hartstonge, K. A., Shortt, J. S., … Kemp, R. A. (2023). Changes in immune cell populations following KappaMab, lenalidomide and low-dose dexamethasone treatment in multiple myeloma. Clinical & Translational Immunology, 12, e1478. doi: 10.1002/cti2.1478 Journal - Research Article

Major, G., Longoni, A., Simcock, J., Magon, N. J., Harte, J., Bathish, B., Kemp, R., Woodfield, T., & Lim, K. S. (2023). Clinical applicability of visible light-mediated cross-linking for structural soft tissue reconstruction. Advanced Science, 10, 2300538. doi: 10.1002/advs.202300538 Journal - Research Article

Kemp, R. (2022, October). Some T cells are more equal than others. University of Otago, Dunedin, New Zealand. [Inaugural Professorial Lecture]. Other Research Output

2024

Authored Book - Research

Kemp, R. A., & Brown, D. M. (2024). How to be a scientist: Critical thinking in the life sciences. Boca Raton, FL: CRC Press, 252p. doi: 10.1201/9781003326366

Conference Contribution - Published proceedings: Abstract

2023

Journal - Research Article

2022

Journal - Research Article

Angus, H. C. K., Urbano, P. C. M., Laws, G. A., Fan, S., Gadeock, S., Schultz, M., … Highton, A. J., & Kemp, R. A. (2022). An autologous colonic organoid-derived monolayer model to study immune: bacterial interactions in Crohn's disease patients. Clinical & Translational Immunology, 11, e1407. doi: 10.1002/cti2.1407

Naqash, A., Stuart, G., Kemp, R., & Wise, L. (2022). Parapoxvirus interleukin-10 homologues vary in their receptor binding, anti-inflammatory, and stimulatory activities. Pathogens, 11, 507. doi: 10.3390/pathogens11050507

Urbano, P. C. M., Angus, H. C. K., Gadeock, S., Schultz, M., & Kemp, R. A. (2022). Assessment of source material for human intestinal organoid culture for research and clinical use. BMC Research Notes, 15, 35. doi: 10.1186/s13104-022-05925-4

Kalff, A., Khong, T., Ramachandran, M., Ho, P. J., Mollee, P., D'Rozario, J., … Norton, S., Kemp, R., … Spencer, A. (2022). Planned withdrawal of dexamethasone after pomalidomide low dose dexamethasone induction for lenalidomide-refractory multiple myeloma (ALLG MM14). Haematologica, 107(1), 321-325. doi: 10.3324/haematol.2021.278655

Conference Contribution - Published proceedings: Abstract

Highton, A., Urbano, P., Fan, L., Laws, G., Schultz, M., & Kemp, R. (2022). Predicting anti-TNF responses in inflammatory bowel disease patients using intestinal organoids. Proceedings of the New Zealand Branch of the Australian and New Zealand Society for Immunology (NZASI) Conference. (pp. 34). Retrieved from https://nzasi2022.com/programme

Laws, G., Angus, H., Fan, L., Urbano, P., Highton, A., Schultz, M., & Kemp, R. (2022). Inflammatory T cells result in epithelial damage in patients with Crohn's disease. Proceedings of the New Zealand Branch of the Australian and New Zealand Society for Immunology (NZASI) Conference. (pp. 26). Retrieved from https://nzasi2022.com/programme

Gaskarth, D., Niemi, G., Morgan, X., & Kemp, R. (2022). Short-chain fatty-acids: Boosting the anti-tumour function of CD8+ T cells. Proceedings of the New Zealand Branch of the Australian and New Zealand Society for Immunology (NZASI) Conference. (pp. 21). Retrieved from https://nzasi2022.com/programme

Costello, R., Rhodes, J., Miller, M., Munro, F., Kemp, R., & Slatter, T. (2022). Association of cancer-associated fibroblast phenotype and frequency with two-point immunoscore in colorectal cancer patients. Proceedings of the New Zealand Branch of the Australian and New Zealand Society for Immunology (NZASI) Conference. (pp. 11). Retrieved from https://nzasi2022.com/programme

Other Research Output

Kemp, R. (2022, October). Some T cells are more equal than others. University of Otago, Dunedin, New Zealand. [Inaugural Professorial Lecture].

2021

Journal - Research Article

Hazlett, J., Niemi, V., Aiderus, A., Powell, K., Wise, L., Kemp, R., & Dunbier, A. K. (2021). Oestrogen deprivation induces chemokine production and immune cell recruitment in in vitro and in vivo models of oestrogen receptor-positive breast cancer. Breast Cancer Research, 23, 95. doi: 10.1186/s13058-021-01472-1

Naciute, M., Kiwitt, T., Kemp, R. A., & Hook, S. (2021). Bacteria biohybrid oral vaccines for colorectal cancer treatment reduce tumor growth and increase immune infiltration. Vaccine, 39, 5589-5599. doi: 10.1016/j.vaccine.2021.08.028

Laws, G. A., Hale, J. D. F., & Kemp, R. A. (2021). Human systemic immune response to ingestion of the oral probiotic Streptococcus salivarius BLIS K12. Probiotics & Antimicrobial Proteins, 13, 1521-1529. doi: 10.1007/s12602-021-09822-3

Journal - Research Other

Marsh-Wakefield, F. M. D., Mitchell, A. J., Norton, S. E., Ashurst, T. M., Leman, J. K. H., Roberts, J. M., Harte, J. E., … Kemp, R. A. (2021). Making the most of high-dimensional cytometry data. Immunology & Cell Biology, 99, 680-696. doi: 10.1111/imcb.12456

Conference Contribution - Published proceedings: Abstract

Tabi-Amponsah, A. D., Stuart, G. S., Kemp, R. A., & Wise, L. M. (2021). Dissecting the receptor signalling events responsible for the immune suppressive and immune stimulatory effects of IL-10. New Zealand Medical Journal, 134(1547), (pp. 144). Retrieved from https://www.nzma.org.nz/journal

Naqash, A., Kemp, R., Glass, M., & Wise, L. (2021). Control of immune cell function by IL-10 proteins derived from viruses. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 46). [Abstract]

Harte, J., Leman, J., Munro, F., McCall, J., McGuire, H., & Kemp, R. (2021). Inhibitory receptor expressing T cells produce functional cytokines and are enriched in the tumour compared to the non-tumour bowel and peripheral blood of patients with colorectal cancer. New Zealand Medical Journal, 134(1537), (pp. 111). Retrieved from https://www.nzma.org.nz/journal

Conference Contribution - Verbal presentation and other Conference outputs

Kemp, R. (2021, July). Why do scientists discount evidence that addresses gender equity? Verbal presentation at the Association for Women in the Sciences (AWIS) Triennial Conference: Embracing Diversity, Dunedin, New Zealand.

2020

Chapter in Book - Research

Leman, J. K. H., Munoz-Erazo, L., & Kemp, R. A. (2020). The intestinal tumour microenvironment. In A. Birbrair (Ed.), Tumor microenvironments in organs: From the brain to the skin: Part A. (pp. 1-22). Cham, Switzerland: Springer. doi: 10.1007/978-3-030-36214-0_1

Journal - Research Article

Niemi, V., Gaskarth, D., & Kemp, R. A. (2020). Extensive variability in the composition of immune infiltrate in different mouse models of cancer. Laboratory Animal Research, 36, 43. doi: 10.1186/s42826-020-00075-9

Naciute, M., Niemi, V., Kemp, R. A., & Hook, S. (2020). Lipid-encapsulated oral therapeutic peptide vaccines reduce tumour growth in an orthotopic mouse model of colorectal cancer. European Journal of Pharmaceutics & Biopharmaceutics, 153, 183-192. doi: 10.1016/j.ejpb.2020.04.020

Journal - Research Other

Munoz-Erazo, L., Rhodes, J. L., Marion, V. C., & Kemp, R. A. (2020). Tertiary lymphoid structures in cancer: Considerations for patient prognosis. Cellular & Molecular Immunology, 17, 570-575. doi: 10.1038/s41423-020-0457-0

Norton, S. E., Leman, J. K. H., Khong, T., Spencer, A., Fazekas de St Groth, B., McGuire, H. M., & Kemp, R. A. (2020). Brick plots: An intuitive platform for visualizing multiparametric immunophenotyped cell clusters. BMC Bioinformatics, 21, 145. doi: 10.1186/s12859-020-3469-y

Angus, H. C. K., Butt, A. G., Schultz, M., & Kemp, R. A. (2020). Intestinal organoids as a tool for inflammatory bowel disease research. Frontiers in Medicine, 6, 334. doi: 10.3389/fmed.2019.00334

Conference Contribution - Published proceedings: Abstract

Dunbier, A. K., Hazlett, J. A., Powell, K., Niemi, G., & Kemp, R. (2020). Investigation of combination treatment an aromatase inhibitor and anti-inflammatory treatment in a model of oestrogen receptor positive breast cancer. Cancer Research, 80(4, Suppl.), P1-03-07. doi: 10.1158/1538-7445.Sabcs19-p1-03-07

Kemp, R., Angus, H., Butt, G., & Schultz, M. (2020). Understanding human Crohn's disease: T cell immunoprofiling and in vitro primary intestinal epithelial monolayer models. Journal of Immunology, 204(1, Suppl.), 224.4. [Abstract]

2019

Chapter in Book - Research

Norton, S., & Kemp, R. (2019). Computational analysis of high-dimensional mass cytometry data from clinical tissue samples. In H. M. McGuire & T. M. Ashhurst (Eds.), Mass cytometry: Methods and protocols: Methods in molecular biology (Vol. 1989). (pp. 295-308). New York, NY: Humana Press. doi: 10.1007/978-1-4939-9454-0_19

Journal - Research Article

Norton, S. E., Ward-Hartstonge, K. A., McCall, J. L., Leman, J. K. H., Taylor, E. S., Munro, F., Black, M. A., … Kemp, R. A. (2019). High-dimensional mass cytometric analysis reveals an increase in effector regulatory T cells as a distinguishing feature of colorectal tumors. Journal of Immunology, 202, 1871-1884. doi: 10.4049/jimmunol.1801368

Lepletier, A., Lutzky, V. P., Mittal, D., Stannard, K., Watkins, T. S., Ratnatunga, C. N., … Kemp, R. A., … Miles, J. J. (2019). The immune checkpoint CD96 defines a distinct lymphocyte phenotype and is highly expressed on tumor-infiltrating T cells. Immunology & Cell Biology, 97, 152-164. doi: 10.1111/imcb.12205

Journal - Research Other

Laws, G. A., & Kemp, R. A. (2019). Probiotics and health: Understanding probiotic trials. New Zealand Medical Journal, 132(1498), 90-96. Retrieved from https://www.nzma.org.nz/journal

Sarfati, D., Jackson, C. G. C. A., Macfarlane, S., Bissett, I., Robson, B., Gurney, J., Kemp, R., … McMenamin, J. (2019). Cancer Care at a Crossroads: Time to make a choice. New Zealand Medical Journal, 132(1493), 6-11. Retrieved from https://www.nzma.org.nz/journal

2018

Journal - Research Article

Leman, J. K. H., Sandford, S. K., Rhodes, J. L., & Kemp, R. A. (2018). Multiparametric analysis of colorectal cancer immune responses. World Journal of Gastroenterology, 24(27), 2995-3005. doi: 10.3748/wjg.v24.i27.2995

Taylor, E. S., McCall, J. L., Shen, S., Girardin, A., Munro, F. M., Black, M. A., Ward-Hartstonge, K. A., & Kemp, R. A. (2018). Prognostic roles for IL-2-producing and CD69⁺ T cell subsets in colorectal cancer patients. International Journal of Cancer, 143(8), 2008-2016. doi: 10.1002/ijc.31598

Conference Contribution - Published proceedings: Abstract

Moloney-Geany, K., Norton, S., Ward-Hartstonge, K., Munro, F., McCall, J., & Kemp, R. (2018). Suppression of effector T cell function in colorectal cancer. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Rhodes, J., McCall, J., Pattison, S., Ward-Hartstonge, K., Sandford, S., Munro, F., Black, M., & Kemp, R. (2018). Refining multiplex immunohistochemistry to quantify in situ immune infiltrate: Improving survival of colorectal cancer patients. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Naciute, M., Niemi, G., Gibson, B., Kemp, R., & Hook, S. (2018). Oral therapeutic vaccination against colorectal cancer. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Hazlett, J., Niemi, G., Kemp, R., & Dunbier, A. (2018). Investigation of combination treatment an aromatase inhibitor and anti-inflammatory treatment in a model of oestrogen receptor positive breast cancer. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Harte, J., Niemi, G., Hook, S., & Kemp, R. (2018). Detection of AH1 antigen specific T cells in a murine colorectal cancer model. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Gaskarth, D., Niemi, G., Highton, A., Hook, S., & Kemp, R. (2018). Characterising T cell response in an orthotopic intracaecal mouse model of colorectal cancer. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Leman, J., McCall, J., Ward-Hartstonge, K., Norton, S., Munro, F., McGuire, H., & Kemp, R. (2018). Characterising dysfunctional T cells in colorectal cancer. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Norton, S., Ward-Hartstonge, K., McCall, J., Leman, J., Shen, S., Taylor, E., Munro, F., Black, M., … Kemp, R. (2018). An increase in effector Tregs is a classifying feature of the immune landscape in colorectal tumours. Proceedings of the New Zealand Society for Oncology (NZSO) Conference. Retrieved from http://www.nzsoncology.org.nz/

Niemi, G. R., Highton, A. J., Hook, S. M., & Kemp, R. A. (2018). Modulating the immune response to colorectal cancer in mice using a cancer vaccine. New Zealand Medical Journal, 131(1470), (pp. 111). Retrieved from https://www.nzma.org.nz/journal

Conference Contribution - Verbal presentation and other Conference outputs

Gaskarth, D. A., Niemi, G. R., Highton, A., Hook, S., & Kemp, R. A. (2018, August). Characterising T cell responses in an orthotopic intracaecal mouse model of colorectal cancer. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Niemi, G. R., Naciute, M., Cockerill, S., & Kemp, R. A. (2018, August). Immunologic considerations of a surgical mouse model of colorectal cancer. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Laws, G., Hale, J., McConnell, M., & Kemp, R. (2018, August). The effect of the probiotic Streptococcus salivarious (BLIS) K12 on human systemic immune responses. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Shirley, S., Kemp, R., Cakebread, J., & Hodgkinson, A. (2018, August). Is the immune system of naïve mice affected by cow's milk? Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Angus, H. C. K., Aluzaite, K., Butt, G. A., Schultz, M., & Kemp, R. A. (2018, August). Novel investigation of Crohn's disease T cell phenotypes and functionality in an in vitro human colonoid model. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Rhodes, J. L., McCall, J. L., Pattison, S. T., Ward-Hartstonge, K. A., Sandford, S. K., Munro, F. M., Black, M. A., & Kemp, R. A. (2018, August). Refining multiplex immunohistochemistry to quantify in situ immune infiltrate: Improving survival of colorectal cancer patients. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Hazlett, J., Niemi, G., Kemp, R., & Dunbier, A. (2018, August). Investigation of combination treatment of an aromatase inhibitor and anti-inflammatory treatment in a model of oestrogen receptor positive breast cancer. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Naciute, M., Niemi, G., Gibson, B., Kemp, R., & Hook, S. (2018, August). Immune response to oral therapeutic vaccination against colorectal cancer. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Leman, J., McCall, J., Ward-Hartstonge, K. A., Norton, S., Munro, F., McGuire, H., & Kemp, R. A. (2018, August). Characterising dysfunctional T cells in colorectal cancer. Verbal presentation at the Queenstown Molecular Biology (QMB) and Australasian Society for Immunology New Zealand Branch (ASI-NZ) Joint Meeting, Queenstown, New Zealand.

Other Research Output

Kemp, R. (2018, July). Vision Mātauranga/Responsiveness to Māori statements. Department of Biochemistry, and Department of Microbiology & Immunology, University of Otago, Dunedin, New Zealand. [Department Seminar].

2017

Journal - Research Article

Ward-Hartstonge, K. A., McCall, J. L., McCulloch, T. R., Kamps, A.-K., Girardin, A., Cretney, E., Munro, F. M., & Kemp, R. A. (2017). Inclusion of BLIMP-1⁺ effector regulatory T cells improves the Immunoscore in a cohort of New Zealand colorectal cancer patients: A pilot study. Cancer Immunology, Immunotherapy, 66(4), 515-522. doi: 10.1007/s00262-016-1951-1

Journal - Research Other

Ward-Hartstonge, K. A., & Kemp, R. A. (2017). Regulatory T-cell heterogeneity and the cancer immune response. Clinical & Translational Immunology, 6, e154. doi: 10.1038/cti.2017.43

Conference Contribution - Published proceedings: Abstract

Kemp, R. (2017). Immunology in cancer: Using big data to improve outcomes. New Zealand Dental Journal, 113(4), (pp. 52). [Abstract]

Angus, H., Norton, S., Dunn, E., Aluzaite, K., Gadeock, S., Butt, G., & Kemp, R. (2017). Development of in vitro models for human Crohn's disease. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 4). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html

Niemi, G., Hook, S., & Kemp, R. (2017). Comparison of immune cell infiltrate between subcutaneous melanoma and colon carcinoma mouse models. Proceedings of the University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka. (pp. 62-63). Retrieved from http://www.otago.ac.nz/graduate-research/scholarships/otago643219.html

Hazlett, J., Hunter, B., Kemp, R., & Dunbier, A. (2017). Investigating immune responsiveness in oestrogen receptor positive breast cancer. In A. Blackman, L. Gillman, C. Oliver & D. Dantzic (Eds.), Proceedings of the Inaugural New Zealand Breast Cancer Symposium (NZBCS): United for a Cure through Research. (pp. 52). Auckland, New Zealand: Auckland University of Technology. [Abstract]

Niemi, G., Naciute, M., Highton, A., Gibson, B., Hook, S., & Kemp, R. (2017). Altering the immune response to colorectal cancer in mouse models. Proceedings of the 46th Australasian Society for Immunology (ASI) Annual Scientific Meeting. 341. Retrieved from http://www.asi2017.org/

Niemi, V. R., Highton, A. J., Hook, S. M., & Kemp, R. A. (2017). Comparison of immune cell infiltrate between subcutaneous melanoma and colon carcinoma mouse models. New Zealand Medical Journal, 130(1452), (pp. 78). Retrieved from https://www.nzma.org.nz/journal

Conference Contribution - Verbal presentation and other Conference outputs

Kemp, R. (2017, October). Infiltrating immune cells that predict patient outcome. Invited presentation at the New Zealand Society for Oncology (NZSO) Conference, Auckland, New Zealand.

Angus, H., Aluzaite, K., Schultz, M., Butt, G., & Kemp, R. (2017, July). Investigation into T cell-mediated Crohn's disease. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.

Ward Hartstonge, K. A., McCall, J. L., Kamps, A.-K., McCulloch, T., Cretney, E., Munro, F., & Kemp, R. A. (2017, July). Blimp-1⁺ IL-10-producing regulatory T cells are associated with longer disease-free survival in colorectal cancer. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.

Kennedy, B. R., McCall, J. L., Miller, A. P., Gibbs, D. D., Kemp, R. A., & Currie, M. J. (2017, July). Identifying neutrophil subpopulations in colorectal cancer. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.

Shirley, S., Kemp, R., Hodgkinson, A., & Cakebread, J. (2017, July). Are immune responses in mice affected by cow's milk? Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.

Dunbier, A., Hazlett, J., Wise, L., & Kemp, R. (2017, July). Effect of oestrogen deprivation on chemokine expression and immune cell recruitment in breast cancer. Verbal presentation at the New Zealand Branch of the Australasian Society for Immunology (NZ ASI) Annual Scientific Meeting, Christchurch, New Zealand.

2016

Journal - Research Article

Neumann, S., Shirley, S. A., Kemp, R. A., & Hook, S. M. (2016). Improved antitumor activity of a therapeutic melanoma vaccine through the use of the dual COX-2/5-LO inhibitor licofelone. Frontiers in Immunology, 7(537), 537. doi: 10.3389/fimmu.2016.00537

Highton, A. J., Girardin, A., Bell, G. M., Hook, S. M., & Kemp, R. A. (2016). Chitosan gel vaccine protects against tumour growth in an intracaecal mouse model of cancer by modulating systemic immune responses. BMC Immunology, 17, 39. doi: 10.1186/s12865-016-0178-4

Taylor, E. S., McCall, J. L., Girardin, A., Munro, F. M., Black, M. A., & Kemp, R. A. (2016). Functional impairment of infiltrating T cells in human colorectal cancer. OncoImmunology, 5(11), e1234573. doi: 10.1080/2162402X.2016.1234573

Parayath, N. N., Nehoff, H., Norton, S. E., Highton, A. J., Taurin, S., Kemp, R. A., & Greish, K. (2016). Styrene maleic acid-encapsulated paclitaxel micelles: Antitumor activity and toxicity studies following oral administration in a murine orthotopic colon cancer model. International Journal of Nanomedicine, 11, 3979-3991. doi: 10.2147/IJN.S110251

Dunn, E. T. J., Taylor, E. S., Stebbings, S., Schultz, M., Butt, A. G., & Kemp, R. A. (2016). Distinct immune signatures in the colon of Crohn's disease and ankylosing spondylitis patients in the absence of inflammation. Immunology & Cell Biology, 94(5), 421-429. doi: 10.1038/icb.2015.112

Norton, S. E., Dunn, E. T. J., McCall, J. L., Munro, F., & Kemp, R. A. (2016). Gut macrophage phenotype is dependent on the tumor microenvironment in colorectal cancer. Clinical & Translational Immunology, 5(4), e76. doi: 10.1038/cti.2016.21

Conference Contribution - Published proceedings: Abstract

Kemp, R., Ward Hartstonge, K. A., McCulloch, T., Kamps, A.-K., Cretney, E., & McCall, J. (2016). Infiltrate of effector regulatory T cells predicts outcome in a cohort of New Zealand colorectal cancer patients: A pilot study. Journal of Immunology, 196(1, Suppl. ), 212.3. [Abstract]

Norton, S., Taylor, E., Dunn, E., Munro, F., Black, M., McCall, J., & Kemp, R. (2016). Tumours from patients with colorectal cancer may dysregulate gut macrophage function and phenotype. European Journal of Immunology, 46(Suppl. 1), (pp. 439). doi: 10.1002/eji.201670200

Shen, S., Taylor, E., Ward-Hartstonge, K., McCall, J., & Kemp, R. (2016). Impaired signalling in T cells from patients with colorectal cancer in response to IL-2 and IL-7. European Journal of Immunology, 46(Suppl. 1), (pp. 231). doi: 10.1002/eji.201670200

Highton, A., Niemi, V., Hook, S., & Kemp, R. (2016). Chitosan hydrogel vaccine generates CD8⁺ T cell memory protective in a mouse tumour model of colorectal cancer. European Journal of Immunology, 46(Suppl. 1), (pp. 201). doi: 10.1002/eji.201670200

Ward Hartstonge, K., McCulloch, T., Kamps, A., Cretney, E., Munro, F., McCall, J., & Kemp, R. (2016). Effector regulatory T cells are associated with disease-free survival in colorectal cancer. European Journal of Immunology, 46(Suppl. 1), (pp. 35-36). doi: 10.1002/eji.201670200

Shen, S., Taylor, E. S., Munro, F., McCall, J. L., Ward-Hartstonge, K. A., & Kemp, R. A. (2016). Determining the role of tumour infiltrating IL-2 producing T cells in patients with colorectal cancer. New Zealand Medical Journal, 129(1441), (pp. 109). Retrieved from http://www.nzma.org.nz/journal

2015

Chapter in Book - Research

Highton, A. J., & Kemp, R. A. (2015). Immunological background. In C. Foged, T. Rades, Y. Perrie & S. Hook (Eds.), Subunit vaccine delivery. (pp. 3-14). New York: Springer. doi: 10.1007/978-1-4939-1417-3

Journal - Research Article

Norton, S. E., Ward-Hartstonge, K. A., Taylor, E. S., & Kemp, R. A. (2015). Immune cell interplay in colorectal cancer prognosis. World Journal of Gastrointestinal Oncology, 7(10), 221-232. doi: 10.4251/wjgo.v7.i10.221

Highton, A. J., Kojarunchitt, T., Girardin, A., Hook, S., & Kemp, R. A. (2015). Chitosan hydrogel vaccine generates protective CD8 T cell memory against mouse melanoma. Immunology & Cell Biology, 93, 634-640. doi: 10.1038/icb.2015.14

Conference Contribution - Published proceedings: Abstract

Parayath, N. N., Norton, S., Taurin, S., Kemp, R., & Greish, K. (2015). Styrene maleic acid micelles as a nanocarrier system for oral delivery of paclitaxel. Proceedings of the Australasian Pharmaceutical Science Association and the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (APSA-ASCEPT) Joint Scientific Meeting: Drugs to Medicines: Up Close and Personal. 240. Retrieved from http://www.asceptasm.com/

Kemp, R., Norton, S., Taylor, E., Dunn, E., Munro, F., Black, M., & McCall, J. (2015). Colorectal tumour associated macrophages are more pro-inflammatory than adjacent control bowel tissue macrophage populations. Journal of Immunology, 194(1, Suppl.), TUM6P.1003. [Abstract]

Conference Contribution - Poster Presentation (not in published proceedings)

Ward-Hartstonge, K., McCulloch, T., Cretney, E., Munro, F., McCall, J., & Kemp, R. (2015, August-September). Analysis of specific T cell infiltrate can predict patient prognosis in a NZ cohort of colorectal cancer patients. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Thomson, K., Kemp, R., Brooks, H., & McConnell, M. (2015, November). Probiotic bacteria reduce the pro-inflammatory response by enterocytes in response to bacteria isolated from cases of necrotizing enterocolitis. Verbal presentation at the Toxicology Symposium: Toxicology for the Modern Researcher, Dunedin, New Zealand.

Dunbier, A. K., Hazlett, J. A., Hunter, B. L., Buchanan, S. T., Bundock, A. S., Wise, L. M., Kemp, R. A., & Dowsett, M. (2015, August-September). Determinants of resistance to endocrine therapy in breast cancer. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Kemp, R. (2015, August-September). Using the complex immune response in colorectal cancer to predict patient outcome. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2014

Journal - Research Article

Neumann, S., Burkert, K., Kemp, R., Rades, T., Dunbar, P. R., & Hook, S. (2014). Activation of the NLRP3 inflammasome is not a feature of all particulate vaccine adjuvants. Immunology & Cell Biology, 92, 535-542. doi: 10.1038/icb.2014.21

Conference Contribution - Published proceedings: Abstract

Ward-Hartstonge, K., Taha, A., Hung, N., Kemp, R., & Slatter, T. (2014). Increased CD163 expression defines a subgroup of glioblastoma multiforme. New Zealand Medical Journal, 127(1395). Retrieved from http://www.nzma.org.nz/journal

Conference Contribution - Poster Presentation (not in published proceedings)

Ward Hartstonge, K., Taylor, E., Slatter, T., McCulloch, T., Cretney, E., & Kemp, R. (2014, November). The characterisation and role of effector regulatory T cells in colorectal cancer. Poster session presented at the New Zealand Society of Gastroenterology & New Zealand Nurses Organisation Gastroenterology Section Annual Scientific Meeting, Auckland, New Zealand.

Shirley, S., Hook, S., Kemp, R., & Neumann, S. (2014, November). MDSC and their potential role in therapeutic vaccine formulations. Poster session presented at the Devices for Diagnostics and Drug Delivery (D4) Conference, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Kemp, R. (2014, August). The balance of immune populations in colorectal cancer: A new target for immunotherapy. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2013

Journal - Research Article

Schultz, M., Dunn, E., Taylor, E., Butt, G. A., & Kemp, R. (2013). The Gut Map Project: T cell distribution in inflammation of the gut. Journal of Gastroenterology & Hepatology, 28(Suppl. 3), 588. doi: 10.1111/jgh.12363_2

Kemp, R., Dunn, E., & Schultz, M. (2013). Immunomodulators in inflammatory bowel disease: An emerging role for biologic agents. BioDrugs, 27(6), 585-590. doi: 10.1007/s40259-013-0045-2

Girardin, A., McCall, J., Black, M. A., Edwards, F., Phillips, V., Taylor, E. S., Reeve, A. E., & Kemp, R. A. (2013). Inflammatory and regulatory T cells contribute to a unique immune microenvironment in tumor tissue of colorectal cancer patients. International Journal of Cancer, 132(8), 1842-1850. doi: 10.1002/ijc.27855

Conference Contribution - Published proceedings: Abstract

Kemp, R., Taylor, E., Girardin, A., Munro, F., Black, M., & McCall, J. (2013). Inflammatory and regulatory T cells contribute to a unique immune microenvironment in tumor tissue of colorectal cancer patients. Journal of Immunology, 190(1, Suppl.), 170.29. [Abstract]

Neumann, S., Kemp, R., Dunbar, R., Rades, T., & Hook, S. (2013). Activation of the NLRP3 inflammasome through chitosan nanoparticles and subsequent cytokine production leads to the generation of CD11b⁺ Gr-1⁺ myeloid derived suppressor cells. Proceedings of the 11th Annual Meeting of the Association for Cancer Immunotherapy (CIMT). (pp. 178). Retrieved from http://www.cimt.eu/meetings/archive

Thomson, K., Kemp, R., & McConnell, M. (2013). Probiotic bacteria influence IL-8 production by HT-29 enterocytes in response to enterobacteriaceae. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 166-167). Retrieved from http://www.asi2013.org/

Neumann, S., Young, K., Kemp, R., Painter, G., Dunbar, R., & Hook, S. (2013). Investigating cytotoxic T cell responses to long peptide vaccine formulations. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 158). Retrieved from http://www.asi2013.org/

Highton, A., Hook, S., & Kemp, R. (2013). Immunisation using a sustained release vaccine generates functional CD8 T cell memory. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 156-157). Retrieved from http://www.asi2013.org/

Ward-Hartstonge, K., Taylor, E., Cretney, E., Slatter, T., & Kemp, R. (2013). Effector regulatory T cells in colorectal cancer. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 142). Retrieved from http://www.asi2013.org/

Bell, G., Budhwani, M., Highton, A., Hibma, M., & Kemp, R. (2013). Construction of a melanoma cell line for orthotopic models of cancer. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 132). Retrieved from http://www.asi2013.org/

Taylor, E., Girardin, A., Dunn, E., Munro, F., Black, M., McCall, J., & Kemp, R. (2013). Analysis of T cell subsets in colorectal cancer patients. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 102). Retrieved from http://www.asi2013.org/

Dunn, E., Taylor, E., Schultz, M., Butt, G., & Kemp, R. (2013). Macrophage and T cell distribution in autoimmune inflammation of the gut. Proceedings of the 43rd Australasian Society for Immunology (ASI) Annual Scientific Meeting. (pp. 86). Retrieved from http://www.asi2013.org/

Dunn, E., Taylor, E., Stebbings, S., Schultz, M., Butt, G., & Kemp, R. (2013). T cell distribution in gastrointestinal inflammatory disorders. New Zealand Medical Journal, 126(1387). Retrieved from http://www.nzma.org.nz/journal

Norton, S., Dunn, E., Munro, F., McCall, J., & Kemp, R. (2013). Phenotypic and functional characterisation of human macrophages: A role in colorectal cancer. New Zealand Medical Journal, 126(1386). Retrieved from http://www.nzma.org.nz/journal

Dunn, E., Kemp, R., Schultz, M., & Butt, G. (2013). Long-term in vitro expansion of human intestinal organoids. New Zealand Medical Journal, 126(1374). Retrieved from http://www.nzma.org.nz/journal

Neumann, S., Kemp, R., Rades, T., Dunbar, R., & Hook, S. (2013). Evaluating adjuvant characteristics of particulate formulations. Proceedings of 15th Conference on Formulation and Delivery of Bioactives: Found in Translation. Retrieved from http://bioactives.otago.ac.nz/

Conference Contribution - Poster Presentation (not in published proceedings)

Dunn, E., Taylor, E., Schultz, M., Butt, G., & Kemp, R. (2013, September). Macrophage and T cell distribution in autoimmune inflammation of the gut. Poster session presented at the Division of Health Sciences Research Forum: Foundations for Health: Otago Health Research, Christchurch, New Zealand.

2012

Journal - Research Article

Gordon, S., Young, K., Wilson, R., Rizwan, S., Kemp, R., Rades, T., & Hook, S. (2012). Chitosan hydrogels containing liposomes and cubosomes as particulate sustained release vaccine delivery systems. Journal of Liposome Research, 22(3), 193-204. doi: 10.3109/08982104.2011.637502

Conference Contribution - Published proceedings: Abstract

Dunn, E., Taylor, E., Schultz, M., Butt, G., & Kemp, R. (2012). Macrophage and T cell distribution in autoimmune inflammation of the gut. New Zealand Medical Journal, 125(1367). Retrieved from http://www.nzma.org.nz/journal

Highton, A., Girardin, A., Hook, S., & Kemp, R. (2012). Immunisation using a sustained release vaccine generates CD8 T cell memory population in the gut. New Zealand Medical Journal, 125(1364). Retrieved from http://www.nzma.org.nz/journal

Highton, A., Girardin, A., Hook, S. M., & Kemp, R. A. (2012). Immunisation using sustained release vaccines generates a discrete CD8 T cell memory population in the gut. Proceedings of the New Zealand Chapter of the Controlled Release Society 14th Conference on Formulation and Delivery of Bioactives. Retrieved from http://bioactives.otago.ac.nz/

Conference Contribution - Poster Presentation (not in published proceedings)

Highton, A. J., Girardin, A., Hook, S. M., & Kemp, R. A. (2012, September). Immunisation using sustained release vaccines generates a discrete CD8T cell memory population in the gut. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand.

Taylor, E., Girardin, A., Dunn, E., Munro, F., Black, M., McCall, J., & Kemp, R. (2012, September). T cell subset analysis in human colorectal cancer patients. Poster session presented at the Division of Health Sciences Research Forum: Health Matters: Research Excellence at Otago, Dunedin, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Kemp, R., Day, A., Nolan, A., Tannock, G., & Gearry, R. (2012, June). Who are we (Part I). Panel discussion at the Inaugural GutHealth Network Workshop, Dunedin, New Zealand.

2011

Journal - Research Article

Kemp, R. A., Black, M. A., McCall, J., Yoon, H.-S., Phillips, V., Anjomshoaa, A., & Reeve, A. E. (2011). T cell subpopulations in lymph nodes may not be predictive of patient outcome in colorectal cancer. Journal of Experimental & Clinical Cancer Research, 30, 78. doi: 10.1186/1756-9966-30-78

Conference Contribution - Poster Presentation (not in published proceedings)

Highton, A. J., Girardin, A., Hook, S. M., & Kemp, R. A. (2011, December). Immunisation using sustained release vaccines generates a discrete CD8 T cell memory population in the gut. Poster session presented at the 41st Australasian Society for Immunology (ASI) Annual Meeting, Adelaide, Australia.

Conference Contribution - Verbal presentation and other Conference outputs

Kemp, R. (2011, February). Characterising immunological needs of patients. Invited presentation at the New Zealand Chapter of the Controlled Release Society 13th Conference on Formulation and Delivery of Bioactives, Dunedin, New Zealand.

2010

Journal - Research Article

Ting, Y. T., Coates, T. P., Marti, H. P., Dunn, A. C., Parker, R. M., Pickering, J. W., Jack, R. W., Kemp, R. A., Walker, R. J., & McLellan, A. D. (2010). Urinary soluble HLA-DR is a potential biomarker for acute renal transplant rejection. Transplantation, 89(9), 1071-1078. doi: 10.1097/TP.0b013e3181d15492

Kemp, R. A., Pearson, C. F., Cornish, G. H., & Seddon, B. P. (2010). Evidence of STAT5-dependent and -independent routes to CD8 memory formation and a preferential role for IL-7 over IL-15 in STAT5 activation. Immunology & Cell Biology, 88, 213-219. doi: 10.1038/icb.2009.95

Bouwer, A. L., Netter, P., Kemp, R. A., & McLellan, A. D. (2010). A defined serum-free medium useful for monitoring anti-melanoma responses induced by dendritic cell immunotherapy. Journal of Immunological Methods, 352, 178-181. doi: 10.1016/j.jim.2009.11.001

Conference Contribution - Published proceedings: Abstract

Highton, A., Girardin, A., Hook, S., & Kemp, R. (2010). Site-specific memory T cells generated from sustained antigen-release vaccination. New Zealand Medical Journal. 123(1327). Retrieved from http://journal.nzma.org.nz/journal/123-1327/4493/content.pdf

Prier, J., Girardin, A., & Kemp, R. (2010). Differential requirements for T cell receptor and gamma chain cytokine receptors in naïve and memory T cells. New Zealand Medical Journal. 123(1327). Retrieved from http://journal.nzma.org.nz/journal/123-1327/4493/content.pdf

Prier, J., Girardin, A., & Kemp, R. (2010). Disrupting cell metabolism to enhance memory responses to vaccination. New Zealand Medical Journal, 123(1314). Retrieved from http://journal.nzma.org.nz/journal/123-1314/4120/content.pdf

Conference Contribution - Poster Presentation (not in published proceedings)

Kemp, R., Girardin, A., Yoon, H.-S., Phillips, V., Anjomshoaa, A., & Reeve, A. (2010, August). The presence of Foxp3⁺ T cells in the lymph node as an indicator of patient outcome in colorectal cancer. Poster session presented at the 14th International Congress of Immunology, Kobe, Japan.

Conference Contribution - Verbal presentation and other Conference outputs

Prier, J. E., Girardin, A. T., & Kemp, R. A. (2010, July). Disrupting cell metabolism enhances CD8 T cell memory responses to vaccination. Verbal presentation at the New Zealand Australasian Society for Immunology (NZ ASI) Branch Meeting, Wellington, New Zealand.

Girardin, A., Hook, S. M., Kemp, R. A., & Highton, A. J. (2010, July). Site specific memory T cells generated from slow antigen release vaccination. Verbal presentation at the New Zealand Australasian Society for Immunology (NZ ASI) Branch Meeting, Wellington, New Zealand.

Girardin, A., Phillips, V., Anjomshoaa, A., McCall, J., Dunbar, P. R., Reeve, A., Yoon, H.-S., & Kemp, R. (2010, May). T cell mediated immune responses in colorectal cancer patients. Verbal presentation at the New Zealand Society for Oncology (NZSO) Annual Meeting, Auckland, New Zealand.

2009

Conference Contribution - Published proceedings: Abstract

Kemp, R. A., Yoon, H.-S., Anjomshoaa, A., & Reeve, A. E. (2009). Using T cell responses in the lymph node to predict patient outcome in colorectal cancer. Journal of Immunology. 182(Meeting Abstracts 1). [Abstract]

Ting, Y., Coates, P. T., Marti, H., Dunn, A. C., Parker, R. M., Jack, R. W., Kemp, R. A., Walker, R. J., & McLellan, A. D. (2009). Urinary soluble HLA-DR is a potential biomarker for acute renal transplant rejection. Proceedings of the Australasian Society for Immunology 39th Annual Scientific Meeting. ASI. Retrieved from http://www.asi2009.org/

Saunderson, S. C., Kemp, R. A., & McLellan, A. D. (2009). CD169 (sialoadhesin) mediates sialic acid-dependent binding of exosomes to marginal zone metallophilic macrophages and subcapsular sinus macrophages. Proceedings of the Australasian Society for Immunology 39th Annual Scientific Meeting. ASI. Retrieved from http://www.asi2009.org/

Kemp, R. A., Yoon, H.-S., Phillips, V., Anjomshoaa, A., & Reeve, A. E. (2009). Using T cell responses in the lymph node to predict patient outcome in colorectal cancer. Proceedings of the Australasian Society for Immunology 39th Annual Scientific Meeting. ASI. Retrieved from http://www.asi2009.org/

Bouwer, A. L., Stoitzner, P., Kemp, R. A., & McLellan, A. D. (2009). Natural killer cells activate CD8⁺ T cells at both the priming and challenge phases of an anti-tumour response. Proceedings of the Australasian Society for Immunology 39th Annual Scientific Meeting. ASI. Retrieved from http://www.asi2009.org/

Conference Contribution - Verbal presentation and other Conference outputs

Kemp, R. (2009, November). Vaccination strategies to enhance T cell memory responses. Verbal presentation at the National Immunisation Conference, Auckland, New Zealand.

2008

Conference Contribution - Poster Presentation (not in published proceedings)

Kemp, R., Yoon, H.-S., Phillips, V., Anjomshoaa, A., & Reeve, A. (2008, December). Using T cell responses in the lymph node to predict patient outcome in colorectal cancer. Poster session presented at the Australasian Society for Immunology 38th Annual Scientific Meeting, Canberra, Australia.

Conference Contribution - Verbal presentation and other Conference outputs

Kemp, R., Yoon, H.-S., Phillips, V., Anjomshoaa, A., & Reeve, A. (2008, December). Using T cell responses in the lymph node to predict patient outcome in colorectal cancer. Verbal presentation at the Australasian Society for Immunology 38th Annual Scientific Meeting, Canberra, Australia.

Kemp, R. A., & Seddon, B. P. (2008, June). STAT5 activation is necessary but not sufficient for CD8⁺ memory T cell formation and maintenance. Verbal presentation at the New Zealand Australasian Society for Immunology (NZ ASI) Branch Meeting, Wellington, New Zealand.

2005

Journal - Research Article

Kemp, R. A., Bäckström, B. T., & Ronchese, F. (2005). The phenotype of type 1 and type 2 CD8⁺ T cells activated in vitro is affected by culture conditions and correlates with effector activity. Immunology, 115(3), 315-324. doi: 10.1111/j.1365-2567.2005.02168.x

2004

Journal - Research Article

Begg, D., Kemp, R. A., & Griffin, F. (2004). Normal levels of immunocompetence in possums (Trichosurus vulpecula) exposed to different laboratory housing conditions post capture. Immunology & Cell Biology, 82, 253-256. doi: 10.1046/j.1440-1711.2004.01219.x

2001

Journal - Research Article

Kemp, R. A., & Ronchese, F. (2001). Tumor-specific Tc1 but not Tc2 cells deliver protective anti-tumor immunity. Journal of Immunology, 167, 6497-6502.

Chtanova, T., Kemp, R. A., Sutherland, A., Ronchese, F., & Mackay, C. (2001). Gene microarrays reveal extensive differential gene expression in both CD4+ and CD8+ type 1 and type 2 T cells. Journal of Immunology, 167, 3057-3063.

2000

Journal - Research Article

Ritchie, D., Hermans, I., Lumsden, J., Scanga, C., Roberts, J., Yang, J., Kemp, R. A., & Ronchese, F. (2000). Dendritic cell elimination as an assay of cytotoxic T lymphocyte activity in vivo. Journal of Immunological Methods, 256, 109-117.

1998

Journal - Research Article

Bremer, P. J., Osborne, C. M., Smith, J. J., & Kemp, R. A. (1998). Survival of Listeria monocytogenes in seawater and affect of seawater exposure on thermal resistance. Journal of Applied Microbiology, 85(3), 545-553.

Bremer, P. J., Osborne, C. M., & Kemp, R. A. (1998). Thermal-death times of Hafnia alvei cells in a model suspension and in artifically contaminated hot smoked Kahawai (Arripis trutta). Journal of Food Protection, 61(8), 1047-1051.

1997

Conference Contribution - Verbal presentation and other Conference outputs

Osborne, C. M., Kemp, R. A., Bremer, P. J., & Fletcher, G. C. (1997, July). Control of histamine forming bacteria (Hafnia alvei)during the production of hot smoked kahawai. Verbal presentation at the New Zealand Institute of Food Science and Technology National Conference, Napier.

Bremer, P. J., Osborne, C. M., Kemp, R. A., & Smith, J. J. (1997, July). Survival, recoverability, sublethal injury and alteration of thermal death point of Listeria monocytogenes on exposure to seawater. Verbal presentation at the New Zealand Institute of Food Science and Technology National Conference, Napier.