Research publications 2020 – present
Journal - Research Article
Agbor Epse Muluh, E., McCormack, J. C., Mo, Y., Garratt, M., & Peng, M. (2024). Gustatory and olfactory shifts during pregnancy and the postpartum period: A systematic review and meta-analysis. Physiology & Behavior, 273, 114388. doi: 10.1016/j.physbeh.2023.114388
Anders, S., Breithausen, B., Unichenko, P., Herde, M. K., Minge, D., Abramian, A., … Steinhäuser, C. (2024). Epileptic activity triggers rapid ROCK1-dependent astrocyte morphology changes. GLIA, 72, 643-659. doi: 10.1002/glia.24495
Camon, C., Prescott, M., Neyt, C., Decourt, C., Stout, M. B., Campbell, R. E., & Garratt, M. (2024). Systemic metabolic benefits of 17α-estradiol are not exclusively mediated by ERα in glutamatergic or GABAergic neurons. GeroScience. Advance online publication. doi: 10.1007/s11357-024-01192-2
Clarke, G. S., Li, H., Ladyman, S. R., Young, R. L., Gatford, K. L., & Page, A. J. (2024). Effect of pregnancy on the expression of nutrient-sensors and satiety hormones in mice. Peptides, 172, 171114. doi: 10.1016/j.peptides.2023.171114
Clarke, G. S., Vincent, A. D., Ladyman, S. R., Gatford, K. L., & Page, A. J. (2024). Circadian patterns of behaviour change during pregnancy in mice. Journal of Physiology. Advance online publication. doi: 10.1113/JP285553
Emanuel, R. H. K., Docherty, P. D., Lunt, H., Murray, R., & Campbell, R. E. (2024). Clustering polycystic ovary syndrome laboratory results extracted from a large internet forum with machine learning. Intelligence-Based Medicine, 9, 100135. doi: 10.1016/j.ibmed.2024.100135
Garratt, M., Try, H., Neyt, C., & Brooks, R. C. (2024). Exposure to female olfactory cues hastens reproductive ageing and increases mortality when mating in male mice. Proceedings of the Royal Society B, 291, 20231848. doi: 10.1098/rspb.2023.1848
Higgins, M. B. A., Glendining, K. A., & Jasoni, C. L. (2024). The temporal and spatial pattern of leptin receptor-expressing cells in the developing mouse hypothalamus. Journal of Neuroendocrinology, 36, e13366. doi: 10.1111/jne.13366
Kamstra, K., van der Burg, C., Quertermous, H. M., Muncaster, S., Todd, E. V., Jasoni, C. L., … Gemmell, N. J. (2024). Neuroanatomy of a sex changing fish: The New Zealand spotty wrasse (Notolabrus celidotus) brain atlas. New Zealand Journal of Zoology, 51(2), 228-239. doi: 10.1080/03014223.2023.2216939
Kerbus, R. I., Decourt, C., Inglis, M. A., Campbell, R. E., & Anderson, G. M. (2024). Androgen receptor actions on AgRP neurons are not a major cause of reproductive and metabolic impairments in peripubertally androgenized mice. Journal of Neuroendocrinology, 36, e13370. doi: 10.1111/jne.13370
Khant Aung, Z., Ladyman, S. R., & Brown, R. S. E. (2024). Transient loss of satiety effects of leptin in middle-aged male mice. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.13386
Menezes, F., Wasinski, F., de Souza, G. O., Nunes, A. P., Bernandes, E. S., dos Santos, S. N., … Brown, R. S. E., … Donato, J., Jr (2024). The pattern of growth hormone action in the mouse brain. Endocrinology, bqae057. Advance online publication. doi: 10.1210/endocr/bqae057
Miller, R. A., Harrison, D. E., Cortopassi, G. A., Dehghan, I., Fernandez, E., Garratt, M., … Strong, R. (2024). Lifespan effects in male UM-HET3 mice treated with sodium thiosulfate, 16-hydroxyestriol, and late-start canagliflozin. GeroScience. Advance online publication. doi: 10.1007/s11357-024-01176-2
Richard, S., Zhou, Y., Jasoni, C. L., & Pankhurst, M. W. (2024). Ovarian follicle size or growth rate can both be determinants of ovulatory follicle selection in mice. Biology of Reproduction, 110(1), 127-136. doi: 10.1093/biolre/ioad134
Rizwan, M. Z., Kamstra, K., Pretz, D., Shepherd, P. R., Tups, A., & Grattan, D. R. (2024). Conditional deletion of β-catenin in the mediobasal hypothalamus impairs adaptive energy expenditure in response to high fat diet and exacerbates diet-induced obesity. Journal of Neuroscience. Advance online publication. doi: 10.1523/jneurosci.1666-23.2024
Sawyer, I. L., Evans, M. C., Mamgain, A., Decourt, C., Iremonger, K. J., & Anderson, G. M. (2024). Chemogenetic activation of RFRP neurons reduces LH pulse frequency in female but not male mice. Journal of the Endocrine Society. Advance online publication. doi: 10.1210/jendso/bvae159/7759651
Sequeira-Bisson, I. R., Lu, L. W., Silvestre, M. P., Plank, L. D., Middleditch, N., Acevedo-Fani, A., Parry-Strong, A., … Tups, A., … Krebs, J. D., … Poppitt, S. D. (2024). Glycaemic response to a nut-enriched diet in Asian Chinese adults with normal or high glycaemia: The Tū Ora RCT. Nutrients, 16(13), 2103. doi: 10.3390/nu16132103
Sucquart, I. E., Coyle, C., Rodriguez Paris, V., Prescott, M., Glendining, K. A., Potapov, K., … Campbell, R. E. (2024). Investigating GABA neuron-specific androgen receptor knockout in two hyperandrogenic models of PCOS. Endocrinology, 165, bqae060. doi: 10.1210/endocr/bqae060
Villa, P. A., Ruggiero-ruff, R. E., Jamieson, B. B., Campbell, R. E., & Cross, D. (2024). Obesity alters POMC and kisspeptin neuron crosstalk leading to reduced luteinizing hormone in male mice. Journal of Neuroscience. Advance online publication. doi: 10.1523/JNEUROSCI.0222-24.2024
Anderson, G. M., Hill, J. W., Kaiser, U. B., Navarro, V. M., Ong, K. K., Perry, J. R. B., … Elias, C. F. (2023). Metabolic control of puberty: 60 years in the footsteps of Kennedy and Mitra's seminal work. Nature Reviews Endocrinology. Advance online publication. doi: 10.1038/s41574-023-00919-z
Aquino, N. S. S., Mansano, N. S., Vieira, F. A. S., Silva, K. S. C., Gusmao, D. O., Anderson, G. M., … Szawka, R. E. (2023). RFamide-related peptide 3 signaling via neuropeptide FF receptor stimulates prolactin secretion in female rats. Endocrinology, 164(8), bqad102. doi: 10.1210/endocr/bqad102
Brown, R. S. E., Jacobs, I. M., Khant Aung, Z., Knowles, P. J., Grattan, D. R., & Ladyman, S. R. (2023). High fat diet-induced maternal obesity in mice impairs peripartum maternal behaviour. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.13350
Clarkson, J., Yip, S. H., Porteous, R., Kauff, A., Heather, A. K., & Herbison, A. E. (2023). CRISPR-Cas9 knockdown of ESR1 in preoptic GABA-kisspeptin neurons suppresses the preovulatory surge and estrous cycles in female mice. eLIFE, 12, RP90959. doi: 10.7554/eLife.90959
Decourt, C., Evans, M. C., Inglis, M. A., & Anderson, G. M. (2023). Central irisin signaling is required for normal timing of puberty in female mice. Endocrinology, 164(2). doi: 10.1210/endocr/bqac208
Decourt, C., Watanabe, Y., Evans, M. C., Inglis, M. A., Fisher, L. C., Jasoni, C. L., Campbell, R. E., & Anderson, G. M. (2023). Deletion of androgen receptors from kisspeptin neurons prevents PCOS features in a letrozole mouse model. Endocrinology, 164(6), bqad077. doi: 10.1210/endocr/bqad077
Donaldson, N. M., Prescott, M., Ruddenklau, A., Campbell, R. E., & Desroziers, E. (2023). Maternal androgen excess significantly impairs sexual behavior in male and female mouse offspring: Perspective for a biological origin of sexual dysfunction in PCOS. Frontiers in Endocrinology, 14, 1116482. doi: 10.3389/fendo.2023.1116482
Emanuel, R. H. K., Docherty, P. D., Lunt, H., & Campbell, R. E. (2023). Comparing literature- and subreddit-derived laboratory values in polycystic ovary syndrome (PCOS): Validation of clinical data posted on PCOS Reddit forums. JMIR Formative Research, 7, e44810. doi: 10.2196/44810
Evans, M. C., Wallace, E. G., Ancel, C. M., & Anderson, G. M. (2023). Leptin, but not estradiol, signaling in PACAP neurons modulates puberty onset. Endocrinology, 164(8), bqad097. doi: 10.1210/endocr/bqad097
Garratt, M., Neyt, C., Ladyman, S. R., Pyrski, M., Zufall, F., & Leinders-Zufall, T. (2023). Sensory detection of female olfactory cues as a central regulator of energy metabolism and body weight in male mice. iScience, 26, 106455. doi: 10.1016/j.isci.2023.106455
Hackwell, E. C. R., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2023). Mechanisms of lactation-induced infertility in female mice. Endocrinology, 164(5), bqad049. doi: 10.1210/endocr/bqad049
Han, S. Y., Morris, P. G., Kim, J.-C., Guru, S., Pardo-Navarro, M., Yeo, S.-H., McQuillan, H. J., & Herbison, A. E. (2023). Mechanism of kisspeptin neuron synchronization for pulsatile hormone secretion in male mice. Cell Reports, 42, 111914. doi: 10.1016/j.celrep.2022.111914
Hassan, M., Grattan, D. R., & Leitch, B. (2023). Developmental inhibitory changes in the primary somatosensory cortex of the stargazer mouse model of absence epilepsy. Biomolecules, 13, 186. doi: 10.3390/biom13010186
Herrera, J. J., Pifer, K., Louzon, S., Leander, D., Fiehn, O., Day, S. M., … Garratt, M. (2023). Early or late-life treatment with acarbose or rapamycin improves physical performance and affects cardiac structure in aging mice. Journals of Gerontology Series A, 78(3), 397-406. doi: 10.1093/gerona/glac221
Kerbus, R. I., Inglis, M. A., & Anderson, G. M. (2023). Neuronal Ptpn1 and Socs3 deletion improves metabolism but not anovulation in a mouse PCOS model. Journal of Endocrinology. Advance online publication. doi: 10.1530/JOE-23-0023
Kumar, S. S., Bouwer, G. T., Jackson, M. K., Perkinson, M. R., McDonald, F. J., Brown, C. H., & Augustine, R. A. (2023). Kisspeptin neuron projections to oxytocin neurons are not necessary for parturition in the mouse. Brain Structure & Function, 228, 1535-1548. doi: 10.1007/s00429-023-02670-7
Lissaman, A. C., Girling, J. E., Cree, L. M., Campbell, R. E., & Ponnampalam, A. P. (2023). Androgen signalling in the ovaries and endometrium. Molecular Human Reproduction, 29(6), gaad017. doi: 10.1093/molehr/gaad017
Liu, X., Porteous, R., & Herbison, A. E. (2023). Robust GABAergic regulation of the GnRH neuron distal dendron. Endocrinology, 164(1), bqac194. doi: 10.1210/endocr/bqac194
Power, E. M., Ganeshan, D., & Iremonger, K. J. (2023). Estradiol regulates voltage-gated potassium currents in corticotropin-releasing hormone neurons. Journal of Experimental Biology. Advance online publication. doi: 10.1242/jeb.245222
Pretz, D., Heyward, P. M., Krebs, J., Gruchot, J., Barter, C., Silcock, P., Downes, N., Rizwan, M. Z., Boucsein, A., Bender, J., Burgess, E. J., Boer, G. A., Keerthisinghe, P., Perry, N. B., & Tups, A. (2023). A dahlia flower extract has anti-diabetic properties by improving insulin function in the brain. Life Metabolism, 2(4), load026. doi: 10.1093/lifemeta/load026
Rizwan, M. Z., Kerbus, R., Kamstra, K., Keerthisinghe, P., & Tups, A. (2023). Dietary wheat gluten induces astro- and microgliosis in the hypothalamus of male mice. Journal of Neuroendocrinology, e13326. Advance online publication. doi: 10.1111/jne.13326
Ruddenklau, A., Glendining, K., Prescott, M., & Campbell, R. E. (2023). Validation of a new custom polyclonal progesterone receptor antibody for immunohistochemistry in the female mouse brain. Journal of the Endocrine Society, bvad113. Advance online publication. doi: 10.1210/jendso/bvad113
Smiley, K. O., Phillipps, H. R., Fang, C., Brown, R. S. E., & Grattan, D. R. (2023). Mating-induced prolactin surge is not required for subsequent neurogenesis in male mice. Frontiers in Behavioral Neuroscience, 17, 1227726. doi: 10.3389/fnbeh.2023.1227726
Swart, J. M., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2023). Pups and prolactin are rewarding to virgin female and pregnant mice. Journal of Neuroendocrinology, 35, e13232. doi: 10.1111/jne.13232
Wall, E. G., Desai, R., Khant Aung, Z., Yeo, S. H., Grattan, D. R., Handelsman, D. J., & Herbison, A. E. (2023). Unexpected plasma gonadal steroid and prolactin levels across the mouse estrous cycle. Endocrinology, 164(6), bqad070. doi: 10.1210/endocr/bqad070
Watanabe, Y., Fisher, L., Campbell, R. E., & Jasoni, C. L. (2023). Defining potential targets of prenatal androgen excess: Expression analysis of androgen receptor on hypothalamic neurons in the fetal female mouse brain. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.13302
Abbasi, M., Augustine, R. A., Iremonger, K. J., & Brown, C. H. (2022). Central kisspeptin does not affect ERK1/2 or p38 phosphorylation in oxytocin neurons of late-pregnant rats. International Journal of Molecular Sciences, 23(14), 7729. doi: 10.3390/ijms23147729
Abbasi, M., Perkinson, M. R., Seymour, A. J., Piet, R., Campbell, R. E., Iremonger, K. J., & Brown, C. H. (2022). Local kisspeptin excitation of rat oxytocin neurones in late pregnancy. Journal of Physiology, 600(7), 1753-1770. doi: 10.1113/jp282531
Ancel, C. M., Evans, M. C., Kerbus, R. I., Wallace, E. G., & Anderson, G. M. (2022). Deletion of PTP 1B from from brain neurons partly protects mice from diet-induced obesity and minimally improves fertility. Endocrinology, 163(2), bqab266. doi: 10.1210/endocr/bqab266
Boer, G. A., Hay, D. L., & Tups, A. (2022). Obesity pharmacotherapy: Incretin action in the central nervous system [Review]. Trends in Pharmacological Sciences, 44(1), 50-63. doi: 10.1016/j.tips.2022.11.001
Brown, E. F., Fronius, M., & Brown, C. H. (2022). Vasopressin regulation of maternal body fluid balance in pregnancy and lactation: A role for TRPV channels? Molecular & Cellular Endocrinology, 558, 111764. doi: 10.1016/j.mce.2022.111764
Coyle, C. S., Prescott, M., Handelsman, D. J., Walters, K. A., & Campbell, R. E. (2022). Chronic androgen excess in female mice does not impact luteinizing hormone pulse frequency or putative GABAergic inputs to GnRH neurons. Journal of Neuroendocrinology, 34, e13110. doi: 10.1111/jne.13110
Decourt, C., Connolly, G. A. D. P., Ancel, C., Inglis, M. A., & Anderson, G. M. (2022). Agouti-related peptide neuronal silencing overcomes delayed puberty in neonatally underfed male mice. Journal of Neuroendocrinology, 34, e13190. doi: 10.1111/jne.13190
Emanuel, R. H. K., Roberts, J., Docherty, P. D., Lunt, H., Campbell, R. E., & Möller, K. (2022). A review of the hormones involved in the endocrine dysfunctions of polycystic ovary syndrome and their interactions. Frontiers in Endocrinology, 13, 1017468. doi: 10.3389/fendo.2022.1017468
Evans, M. C., Campbell, R. E., & Anderson, G. M. (2022). Physiological regulation of leptin as an integrative signal of reproductive readiness [Review]. Current Opinion in Pharmacology, 67, 102321. doi: 10.1016/j.coph.2022.102321
Garratt, M., Erturk, I., Alonzo, R., Zufall, F., Leinders-Zufall, T., Pletcher, S. D., & Miller, R. A. (2022). Lifespan extension in female mice by early, transient exposure to adult female olfactory cues. eLIFE, 11, e84060. doi: 10.7554/eLife.84060
Georgescu, T., Khant Aung, Z., Grattan, D. R., & Brown, R. S. E. (2022). Prolactin-mediated restraint of maternal aggression in lactation. PNAS, 119(6), e2116972119. doi: 10.1073/pnas.2116972119
Gouws, J. M., Sherrington, A., Zheng, S., Kim, J. S., & Iremonger, K. J. (2022). Regulation of corticotropin-releasing hormone neuronal network activity by noradrenergic stress signals. Journal of Physiology, 600(19), 4347-4359. doi: 10.1113/JP283328
Isola, J. V. V., Veiga, G. B., de Brito, C. R. C., Alvarado‑Rincón, J. A., Garcia, D. N., Zanini, B. M., … Garratt, M., … Stout, M. B. (2022). 17α-estradiol does not adversely affect sperm parameters or fertility in male mice: Implications for reproduction-longevity trade-offs. GeroScience. doi: 10.1007/s11357-022-00601-8
Jamieson, B. B., Kim, J. S., & Iremonger, K. J. (2022). Cannabinoid and vanilloid pathways mediate opposing forms of synaptic plasticity in corticotropin-releasing hormone neurons. Journal of Neuroendocrinology, 34, e13084. doi: 10.1111/jne.13084
Jamieson, B. B., Moore, A. M., Lohr, D. B., Thomas, S. X., Coolen, L. M., Lehman, M. N., Campbell, R. E., & Piet, R. (2022). Prenatal androgen treatment impairs the suprachiasmatic nucleus arginine-vasopressin to kisspeptin neuron circuit in female mice. Frontiers in Endocrinology, 13, 951344. doi: 10.3389/fendo.2022.951344
Kamstra, K., Rizwan, M. Z., Grattan, D. R., Horsfield, J. A., & Tups, A. (2022). Leptin regulates glucose homeostasis via the canonical Wnt pathway in the zebrafish. FASEB Journal, 36, e22207. doi: 10.1096/fj.202101764R
Khant Aung, Z., Masih, R. R., Desroziers, E., Campbell, R. E., & Brown, R. S. E. (2022). Enhanced pup retrieval behaviour in a mouse model of polycystic ovary syndrome. Journal of Neuroendocrinology, 34, e13206. doi: 10.1111/jne.13206
McQuillan, H. J., Clarkson, J., Kauff, A., Han, S. Y., Yip, S. H., Cheong, I., Porteous, R., Heather, A. K., & Herbison, A. E. (2022). Definition of the estrogen negative feedback pathway controlling the GnRH pulse generator in female mice. Nature Communications, 13, 7433. doi: 10.1038/s41467-022-35243-z
Ohline, S. M., Liu, X., Ibrahim, M. F., Mockett, B. G., Empson, R. M., Abraham, W. C., Iremonger, K. J., & Jones, P. P. (2022). Altered membrane properties but unchanged intrinsic excitability and spontaneous postsynaptic currents in an aged APPswe/PS1dE9 model of Alzheimer’s disease. Frontiers in Cellular Neuroscience, 16, 958876. doi: 10.3389/fncel.2022.958876
Perkinson, M. R., Kirchner, M. K., Zhang, M., Augustine, R. A., Stern, J. E., & Brown, C. H. (2022). α-Melanocyte-stimulating hormone inhibition of oxytocin neurons switches to excitation in late pregnancy and lactation. Physiological Reports, 10, e15226. doi: 10.14814/phy2.15226
Phillipps, H. R., Khant Aung, Z., & Grattan, D. R. (2022). Elevated prolactin secretion during proestrus in mice: Absence of a defined surge. Journal of Neuroendocrinology, 34, e13129. doi: 10.1111/jne.13129
Radecki, K. C., Ford, M. J., Phillipps, H. R., Lorenson, M. Y., Grattan, D. R., Yamanaka, Y., & Walker, A. M. (2022). Multiple cell types in the oviduct express the prolactin receptor. FASEB BioAdvances, 4, 485-504. doi: 10.1096/fba.2022-00004
Salzano, G., Robert, V., Lomet, D., Decourt, C., Hommet, E., Derouin-Tochon, F., … Beltramo, M. (2022). A customized long acting formulation of the kisspeptin analog C6 triggers ovulation in anestrus ewe. Journal of Endocrinology, 34, e13121. doi: 10.1111/jne.13121
Silva, M. S. B., & Campbell, R. E. (2022). Polycystic Ovary Syndrome and the neuroendocrine consequences of androgen excess. Comprehensive Physiology, 12, 3347-3369. doi: 10.1002/cphy.c210025
Smiley, K. O., Brown, R. S. E., & Grattan, D. R. (2022). Prolactin action is necessary for parental behavior in male mice. Journal of Neuroscience, 42(44), 8308-8327. doi: 10.1523/jneurosci.0558-22.2022
Zhou, Y., Neyt, C., Batchelor, N. J., Kelley, R. L., Jaafar Amsak, K., Anderson, G. M., Oorschot, D. E., Jasoni, C. L., Girling, J. E., & Pankhurst, M. W. (2022). Fetal resorption coincides with dysregulated LH secretion in AMH-overexpressing mice. Journal of Endocrinology, 253(2), 53-62. doi: 10.1530/joe-21-0430
Zhou, Y., Richard, S., Batchelor, N. J., Oorschot, D. E., Anderson, G. M., & Pankhurst, M. W. (2022). Anti-Müllerian hormone-mediated preantral follicle atresia is a key determinant of antral follicle count in mice. Human Reproduction, 37(11), 2635-2645. doi: 10.1093/humrep/deac204
Angelopoulou, E., Inquimbert, P., Klosen, P., Anderson, G., Kalsbeek, A., & Simonneaux, V. (2021). Daily and estral regulation of RFRP-3 neurons in the female mice. Journal of Circadian Rhythms, 19(1), 4. doi: 10.5334/jcr.212
Aoki, M., Gamayun, I., Wyatt, A., Grünewald, R., Simon-Thomas, M., Philipp, S. E., … Grattan, D. R., & Boehm, U. (2021). Prolactin-sensitive olfactory sensory neurons regulate male preference in female mice by modulating responses to chemosensory cues. Science Advances, 7(41), eabg4074. doi: 10.1126/sciadv.abg4074
Debarba, L. K., Jayarathne, H. S. M., Miller, R. A., Garratt, M., & Sadagurski, M. (2021). 17-a-estradiol has sex-specific effects on neuroinflammation that are partly reversed by gonadectomy. Journals of Gerontology Series A. doi: 10.1093/gerona/glab216
Elenis, E., Desroziers, E., Persson, S., Sundström Poromaa, I., & Campbell, R. E. (2021). Early initiation of anti-androgen treatment is associated with increased probability of spontaneous conception leading to childbirth in women with polycystic ovary syndrome: A population-based multiregistry cohort study in Sweden. Human Reproduction, 36(5), 1427-1435. doi: 10.1093/humrep/deaa357
Freeman, A. K., Glendining, K. A., & Jasoni, C. L. (2021). Developmental genes controlling neural circuit formation are expressed in the early postnatal hypothalamus and cellular lining of the third ventricle. Journal of Neuroendocrinology, 33(9), e13020. doi: 10.1111/jne.13020
Garratt, M., Try, H., & Brooks, R. C. (2021). Access to females and early life castration individually extend maximal but not median lifespan in male mice. GeroScience, 43, 1437-1446. doi: 10.1007/s11357-020-00308-8
Henneberger, C., Bard, L., Panatier, A., Reynolds, J. P., Kopach, O., Medvedev, N. I., … Herde, M. K., … Rusakov, D. A. (2021). LTP induction boosts glutamate spillover by driving withdrawal of astroglia. Neuron, 108, 919-936. doi: 10.1016/j.neuron.2020.08.030
Jamieson, B. B., Bouwer, G. T., Campbell, R. E., & Piet, R. (2021). Estrous cycle plasticity in the central clock output to kisspeptin neurons: Implications for the preovulatory surge. Endocrinology, 162(6), 1-20. doi: 10.1210/endocr/bqab071
Khant Aung, Z., Kokay, I. C., Grattan, D. R., & Ladyman, S. R. (2021). Prolactin-induced adaptation in glucose homeostasis in mouse pregnancy is mediated by the pancreas and not in the forebrain. Frontiers in Endocrinology, 12, 765976. doi: 10.3389/fendo.2021.765976
Ladyman, S. R., & Brooks, V. L. (2021). Central actions of insulin during pregnancy and lactation [Invited review]. Journal of Neuroendocrinology, 33, e12946. doi: 10.1111/jne.12946
Ladyman, S. R., Carter, K. M., Gillett, M. L., Khant Aung, Z., & Grattan, D. R. (2021). A reduction in voluntary physical activity in early pregnancy in mice is mediated by prolactin. eLIFE, 10, e62260. doi: 10.7554/eLife.62260
Ladyman, S. R., Larsen, C. M., Taylor, R. S., Grattan, D. R., & McCowan, L. M. E. (2021). Case–control study of prolactin and placental lactogen in SGA pregnancies. Reproduction & Fertility, 2(4), 244-250. doi: 10.1530/RAF-21-0020
Li, T., Jia, S.-W., Hou, D., Liu, X., Li, D., Liu, Y., … Brown, C. H., & Wang, Y.-F. (2021). Intranasal oxytocin restoration of maternal behavior and oxytocin neuronal activity in the supraoptic nucleus in rat dams with pre-labor cesarean delivery. Neuroscience, 468, 235-246. doi: 10.1016/j.neuroscience.2021.06.020
Liu, X., Yeo, S.-H., McQuillan, H. J., Herde, M. K., Hessler, S., Cheong, I., Porteous, R., & Herbison, A. E. (2021). Highly redundant neuropeptide volume co-transmission underlying episodic activation of the GnRH neuron dendron. eLIFE, 10, e62455. doi: 10.7554/eLife.62455
Loehfelm, A., Rizwan, M. Z., & Tups, A. (2021). A New Zealand green-lipped mussel oil-enriched high-fat diet exhibits beneficial effects on body weight and metabolism in mice. British Journal of Nutrition, 125(9), 972-982. doi: 10.1017/s0007114520002342
Mamgain, A., Sawyer, I. L., Timajo, D. A. M., Rizwan, M. Z., Evans, M. C., Ancel, C. M., Inglis, M. A., & Anderson, G. M. (2021). RFamide-related peptide neurons modulate reproductive function and stress responses. Journal of Neuroscience, 41(3), 474-488. doi: 10.1523/JNEUROSCI.1062-20.2020
Minge, D., Domingos, C., Unichenko, P., Behringer, C., Pauletti, A., Anders, S., Herde, M. K., … Henneberger, C. (2021). Heterogeneity and development of fine astrocyte morphology captured by diffraction-limited microscopy. Frontiers in Cellular Neuroscience, 15, 669280. doi: 10.3389/fncel.2021.669280
Nair, B. B., Khant Aung, Z., Porteous, R., Prescott, M., Glendining, K. A., Jenkins, D. E., Augustine, R. A., Silva, M. S. B., Yip, S. H., Bouwer, G. T., Brown, C. H., Jasoni, C. L., Campbell, R. E., Bunn, S. J., Anderson, G. M., Grattan, D. R., Herbison, A. E., & Iremonger, K. J. (2021). Impact of chronic variable stress on neuroendocrine hypothalamus and pituitary in male and female C57BL/6J mice. Journal of Neuroendocrinology, 33, e12972. doi: 10.1111/jne.12972
Perkinson, M., Augustine, R. A., Bouwer, G. T., Brown, E. F., Cheong, I., Seymour, A. J., Fronius, M., & Brown, C. H. (2021). Plasticity in intrinsic excitability of hypothalamic magnocellular neurosecretory neurons in late-pregnant and lactating rats. International Journal of Molecular Sciences, 22(13), 7140. doi: 10.3390/ijms22137140
Power, E. M., & Iremonger, K. J. (2021). Plasticity of intrinsic excitability across the estrous cycle in hypothalamic CRH neurons. Scientific Reports, 11(1), 16700. doi: 10.1038/s41598-021-96341-4
Pretz, D., Le Foll, C., Rizwan, M. Z., Lutz, T. A., & Tups, A. (2021). Hyperleptinemia as a contributing factor for the impairment of glucose intolerance in obesity. FASEB Journal, 35, e21216. doi: 10.1096/fj.202001147R
Roy, R. K., Althammer, F., Seymour, A. J., Du, W., Biancardi, V. C., Hamm, J. P., … Brown, C. H., & Stern, J. E. (2021). Inverse neurovascular coupling contributes to positive feedback excitation of vasopressin neurons during a systemic homeostatic challenge. Cell Reports, 37(5), 109925. doi: 10.1016/j.celrep.2021.109925
Sati, A., Prescott, M., Holland, S., Jasoni, C. L., Desroziers, E., & Campbell, R. E. (2021). Morphological evidence indicate a role for microglia in shaping the polycystic ovary syndrome (PCOS)-like brain. Journal of Neuroendocrinology, 33, e12999. doi: 10.1111/jne.12999
Sethi, S., Augustine, R. A., Bouwer, G. T., Perkinson, M. R., Cheong, I., Bussey, C. T., Schwenke, D. O., Brown, C. H., & Lamberts, R. R. (2021). Increased neuronal activation in sympathoregulatory regions of the brain and spinal cord in type 2 diabetic rats. Journal of Neuroendocrinology, 33, e13016. doi: 10.1111/jne.13016
Sucquart, I. E., Nagarkar, R., Edwards, M. C., Paris, V. R., Aflatounian, A., Bertoldo, M. J., Campbell, R. E., … Walters, K. A. (2021). Neurokinin 3 receptor antagonism ameliorates key metabolic features in a hyperandrogenic PCOS mouse model. Endocrinology, 162(5), 1-15. doi: 10.1210/endocr/bqab020
Sugrue, V. J., Zoller, J. A., Narayan, P., Lu, A. T., Ortega-Recalde, O. J., Grant, M. J., … Bond, D. M., … Garratt, M., … Hore, T. A., & Horvath, S. (2021). Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci. eLIFE, 10, e64932. doi: 10.7554/eLife.64932
Swart, J. M., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2021). Changes in maternal motivation across reproductive states in mice: A role for prolactin receptor activation on GABA neurons. Hormones & Behavior, 135, 105041. doi: 10.1016/j.yhbeh.2021.105041
Watanabe, Y., Prescott, M., Campbell, R. E., & Jasoni, C. L. (2021). Prenatal androgenization causes expression changes of progesterone and androgen receptor mRNAs in the arcuate nucleus of female mice across development. Journal of Neuroendocrinology, 33, e13058. doi: 10.1111/jne.13058
Yeo, S.-H., Herde, M. K., & Herbison, A. E. (2021). Morphological assessment of GABA and glutamate inputs to GnRH neurons in intact female mice using expansion microscopy. Journal of Neuroendocrinology, e13021. doi: 10.1111/jne.13021
Yip, S. H., Campos, P., Liu, X., Porteous, R., & Herbison, A. E. (2021). Innervation of GnRH neuron distal projections and activation by kisspeptin in a new GnRH-Cre rat model. Endocrinology, 162(1), bqaa186. doi: 10.1210/endocr/bqaa186
Yip, S. H., Liu, X., Hessler, S., Cheong, I., Porteous, R., & Herbison, A. E. (2021). Indirect suppression of pulsatile LH secretion by CRH neurons in the female mouse. Endocrinology, 162(3), 1-17. doi: 10.1210/endocr/bqaa237
Barad, Z., Khant Aung, Z., Grattan, D. R., Ladyman, S. R., & Brown, R. S. E. (2020). Impaired prolactin transport into the brain and functional responses to prolactin in aged male mice. Journal of Neuroendocrinology, 32, e12889. doi: 10.1111/jne.12889
Beltramo, M., Robert, V., & Decourt, C. (2020). The kisspeptin system in domestic animals: What we know and what we still need to understand of its role in reproduction. Domestic Animal Endocrinology, 73, 106466. doi: 10.1016/j.domaniend.2020.106466
Coutinho, E. A., Prescott, M., Hessler, S., Marshall, C. J., Herbison, A. E., & Campbell, R. E. (2020). Activation of a classic hunger circuit slows luteinizing hormone pulsatility. Neuroendocrinology, 110(7-8), 671-687. doi: 10.1159/000504225
Dias, G. J., Ramesh, N., Neilson, L., Cornwall, J., Kelly, R. J., & Anderson, G. M. (2020). The adaptive immune response to porous regenerated keratin as a bone graft substitute in an ovine model. International Journal of Biological Macromolecules, 165, 100-106. doi: 10.1016/j.ijbiomac.2020.09.133
Focke, C. M. B., & Iremonger, K. J. (2020). Rhythmicity matters: Circadian and ultradian patterns of HPA axis activity. Molecular & Cellular Endocrinology, 501, 110652. doi: 10.1016/j.mce.2019.110652
Garratt, M., Try, H., Smiley, K. O., Grattan, D. R., & Brooks, R. C. (2020). Mating in the absence of fertilization promotes a growth-reproduction versus lifespan trade-off in female mice. PNAS, 117(27), 15748-15754. doi: 10.1073/pnas.2003159117
Georgescu, T., Ladyman, S. R., Brown, R. S. E., & Grattan, D. R. (2020). Acute effects of prolactin on hypothalamic prolactin receptor expressing neurones in the mouse. Journal of Neuroendocrinology, 32, e12908. doi: 10.1111/jne.12908
Georgescu, T., Lyons, D., Doslikova, B., Garcia, A. P., Marston, O., Burke, L. K., … Heisler, L. K. (2020). Neurochemical characterization of brainstem pro-opiomelanocortin cells. Endocrinology, 161(4), bqaa032. doi: 10.1210/endocr/bqaa032
Glendining, K. A., Higgins, M. B. A., Fisher, L. C., & Jasoni, C. L. (2020). Maternal obesity modulates sexually dimorphic epigenetic regulation and expression of leptin receptor in offspring hippocampus. Brain, Behavior & Immunity, 88, 151-160. doi: 10.1016/j.bbi.2020.03.006
Gustafson, P., Ladyman, S. R., McFadden, S., Larsen, C., Khant Aung, Z., Brown, R. S. E., Bunn, S. J., & Grattan, D. R. (2020). Prolactin receptor-mediated activation of pSTAT5 in the pregnant mouse brain. Journal of Neuroendocrinology, 32, e12901. doi: 10.1111/jne.12901
Han, S. Y., Cheong, I., McLennan, T., & Herbison, A. E. (2020). Neural determinants of pulsatile luteinizing hormone secretion in male mice. Endocrinology, 161(2), 1-10. doi: 10.1210/endocr/bqz045
Herbison, A. E. (2020). A simple model of estrous cycle negative and positive feedback regulation of GnRH secretion. Frontiers in Neuroendocrinology, 57, 100837. doi: 10.1016/j.yfrne.2020.100837
Herde, M. K., Bohmbach, K., Domingos, C., Vana, N., Komorowska-Müller, J. A., Passlick, S., … Henneberger, C. (2020). Local efficacy of glutamate uptake decreases with synapse size. Cell Reports, 32(12), 108182. doi: 10.1016/j.celrep.2020.108182
Herrera, J. J., Louzon, S., Pifer, K., Leander, D., Merrihew, G. E., Park, J. H., … Garratt, M. (2020). Acarbose has sex-dependent and -independent effects on age-related physical function, cardiac health, and lipid biology. JCI Insight, 5(21), e137474. doi: 10.1172/jci.insight.137474
Hessler, S., Liu, X., & Herbison, A. E. (2020). Direct inhibition of arcuate kisspeptin neurones by neuropeptide Y in the male and female mouse. Journal of Neuroendocrinology, 32(5), e12849. doi: 10.1111/jne.12849
Khant Aung, Z., Grattan, D. R., & Ladyman, S. R. (2020). Pregnancy-induced adaptation of central sensitivity to leptin and insulin. Molecular & Cellular Endocrinology, 516, 110933. doi: 10.1016/j.mce.2020.110933
Kokay, I. C., Grattan, D. R., & Murray, J. F. (2020). Prolactin maintains transient melanin-concentrating hormone expression in the medial preoptic area during established lactation. Journal of Neuroendocrinology, 32, e12827. doi: 10.1111/jne.12827
Lemaître, J.-F., Ronget, V., Tidière, N., Allainé, D., Berger, V., Cohas, A., … Garratt, M., … Gaillard, J.-M. (2020). Sex differences in adult lifespan and aging rates of mortality across wild mammals. PNAS, 117(15), 8546-8553. doi: 10.1073/pnas.1911999117
Loehfelm, A., Elder, M. K., Boucsein, A., Jones, P. P., Williams, J. M., & Tups, A. (2020). Docosahexaenoic acid prevents palmitate-induced insulin-dependent impairments of neuronal health. FASEB Journal, 34, 4635-4652. doi: 10.1096/fj.201902517R
Lopez-Vicchi, F., Ladyman, S. R., Ornstein, A. M., Gustafson, P., Knowles, P., Luque, G. M., Grattan, D. R., & Becu-Villalobos, D. (2020). Chronic high prolactin levels impact on gene expression at discrete hypothalamic nuclei involved in food intake. FASEB Journal, 34, 3902-3914. doi: 10.1096/fj.201902357R
Marshall, C. J., Prescott, M., & Campbell, R. E. (2020). Investigating the NPY/AgRP/GABA to GnRH neuron circuit in prenatally androgenized PCOS-like mice. Journal of the Endocrine Society, 4(11), bvaa129. doi: 10.1210/jendso/bvaa129
Paige, C., Barba-Escobedo, P. A., Mecklenburg, J., Patil, M., Goffin, V., Grattan, D. R., … Price, T. J. (2020). Neuroendocrine mechanisms governing sex differences in hyperalgesic priming involve prolactin receptor sensory neuron signaling. Journal of Neuroscience, 40(37), 7080-7090. doi: 10.1523/jneurosci.1499-20.2020
Silva, J. F., Henriques, P. C., Campideli-Santana, A. C., Araujo-Lopes, R., Aquino, N. S. S., Hipolito, L. T. M., … Grattan, D. R., & Szawka, R. E. (2020). Estradiol potentiates but is not essential for prolactin-induced suppression of luteinizing hormone pulses in female rats. Endocrinology, 161, 1-14. doi: 10.1210/endocr/bqaa022
Stagkourakis, S., Smiley, K. O., Williams, P., Kakadellis, S., Ziegler, K., Bakker, J., Brown, R. S. E., … Grattan, D. R., & Broberger, C. (2020). A neuro-hormonal circuit for paternal behavior controlled by a hypothalamic network oscillation. Cell, 182, 960-975. doi: 10.1016/j.cell.2020.07.007
Stener-Victorin, E., Padmanabhan, V., Walters, K. A., Campbell, R. E., Benrick, A., Giacobini, P., … Abbott, D. H. (2020). Animal models to understand the etiology and pathophysiology of polycystic ovary syndrome. Endocrine Reviews, 41, 538-576. doi: 10.1210/endrev/bnaa010
Wang, L., Guo, W., Shen, X., Yeo, S., Long, H., Wang, Z., … Herbison, A. E., & Kuang, Y. (2020). Different dendritic domains of the GnRH neuron underlie the pulse and surge modes of GnRH secretion in female mice. eLIFE, 9, e53945. doi: 10.7554/eLife.53945
Yip, S. H., Araujo-Lopes, R., Szawka, R. E., York, J., Hyland, B., Grattan, D. R., & Bunn, S. J. (2020). Morphological plasticity of the tuberoinfundibular dopaminergic neurons in the rat during the estrous cycle and lactation. Journal of Neuroendocrinology, 32(11), e12884. doi: 10.1111/jne.12884
Journal - Research Other
Campbell, R. E. (2024). Beyond the ovary: Rewiring our perspective on polycystic ovary syndrome. Nature Reviews Endocrinology, 97, 104850. doi: 10.1038/s41574-024-00963-3
Grattan, D. R. (2024). Does the brain make prolactin? Journal of Neuroendocrinology, e13432. Advance online publication. doi: 10.1111/jne.13432
Le Tissier, P. R., & Grattan, D. R. (2024). Physiology is all about interactions: The prolactin and growth hormone systems as exemplars. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.13416
Anderson, G. M. (2023). A neuronal circuit for stress-induced reproductive suppression. Endocrinology, 164(3), bqad018. doi: 10.1210/endocr/bqad018
Evans, M. C., & Anderson, G. M. (2023). The role of RFRP neurons in the allostatic control of reproductive function. International Journal of Molecular Sciences, 24(21), 15851. doi: 10.3390/ijms242115851
Georgescu, T. (2023). The role of maternal hormones in regulating autonomic functions during pregnancy. Journal of Neuroendocrinology. Advance online publication. doi: 10.1111/jne.13348
Glendining, K. A., & Campbell, R. E. (2023). Recent advances in emerging PCOS therapies. Current Opinion in Pharmacology, 68, 102345. doi: 10.1016/j.coph.2022.102345
Goffin, V., Becu-Villalobos, D., Popovic, V., & Grattan, D. R. (2023). Editorial: Towards targeting prolactin signaling in human diseases: Stimulate or inhibit? Frontiers in Endocrinology, 14, 1213895. doi: 10.3389/fendo.2023.1213895
McCormack, J. C., Roberts, R., Garratt, M., Wang, T., Hayes, J., & Peng, M. (2023). Longitudinal study of Energy, Neurosensory and Eating Responses durinG pregnancY (ENERGY cohort): A study protocol. Clinical Nutrition ESPEN. Advance online publication. doi: 10.1016/j.clnesp.2023.01.033
Sati, A., Desroziers, E., & Campbell, R. E. (2023). Microglia: Sculptors of the polycystic ovary syndrome (PCOS)-like brain? Reproduction. Advance online publication. doi: 10.1530/rep-22-0343
Campbell, R. E., Coolen, L. M., Hoffman, G. E., & Hrabovszky, E. (2022). Highlights of neuroanatomical discoveries of the mammalian gonadotropin-releasing hormone system. Journal of Neuroendocrinology, 34, e13115. doi: 10.1111/jne.13115
McCartney, C. R., Campbell, R. E., Marshall, J. C., & Moenter, S. M. (2022). The role of gonadotropin-releasing hormone neurons in polycystic ovary syndrome [Invited]. Journal of Neuroendocrinology, 34, e13093. doi: 10.1111/jne.13093
Boucsein, A., Kamstra, K., & Tups, A. (2021). Central signalling cross-talk between insulin and leptin in glucose and energy homeostasis [Invited]. Journal of Neuroendocrinology, 33, e12944. doi: 10.1111/jne.12944
Clarke, G. S., Gatford, K. L., Young, R. L., Grattan, D. R., Ladyman, S. R., & Page, A. J. (2021). Maternal adaptations to food intake across pregnancy: Central and peripheral mechanisms. Obesity, 29(11), 1813-1824. doi: 10.1002/oby.23224
Evans, M. C., Hill, J. W., & Anderson, G. M. (2021). Role of insulin in the neuroendocrine control of reproduction [Invited]. Journal of Endocrinology, 33, e12930. doi: 10.1111/jne.12930
Evans, M. C., Lord, R. A., & Anderson, G. M. (2021). Multiple leptin signalling pathways in the control of metabolism and fertility: A means to different ends? International Journal of Molecular Sciences, 22, 9210. doi: 10.3390/ijms22179210
Georgescu, T., Lyons, D., & Heisler, L. K. (2021). Role of serotonin in body weight, insulin secretion and glycaemic control. Journal of Neuroendocrinology, 33(4), e12960. doi: 10.1111/jne.12960
Georgescu, T., Swart, J. M., Grattan, D. R., & Brown, R. S. E. (2021). The prolactin family of hormones as regulators of maternal mood and behavior. Frontiers in Global Women's Health, 2, 767467. doi: 10.3389/fgwh.2021.767467
Grattan, D. R., & Andrews, Z. B. (2021). Insulin as a neuroendocrine hormone. Journal of Neuroendocrinology, 33, e12966. doi: 10.1111/jne.12966
Perkinson, M. R., Kim, J. S., Iremonger, K. J., & Brown, C. H. (2021). Visualising oxytocin neurone activity in vivo: The key to unlocking central regulation of parturition and lactation [Invited review]. Journal of Neuroendocrinology, 33, e13012. doi: 10.1111/jne.13012
Porteous, R., Haden, P., Hackwell, E. C. R., Singline, A. J., Herde, M. K., Desai, R., … Grattan, D. R., & Herbison, A. E. (2021). Reformulation of PULSAR for analysis of pulsatile LH secretion and a revised model of estrogen negative feedback in mice. Endocrinology, 162(11). doi: 10.1210/endocr/bqab165
Brown, C. H., Ludwig, M., Tasker, J. G., & Stern, J. E. (2020). Somato-dendritic vasopressin and oxytocin secretion in endocrine and autonomic regulation. Journal of Neuroendocrinology, 32, e12856. doi: 10.1111/jne.12856
Garratt, M. (2020). Why do sexes differ in lifespan extension? Sex-specific pathways of aging and underlying mechanisms for dimorphic responses. Nutrition & Healthy Aging, 5, 247-259. doi: 10.3233/NHA-190067
Glendining, K. A., Fisher, L. C., & Jasoni, C. L. (2020). Maternal obesity modulates expression of Satb2 in hypothalamic VMN of female offspring [Communication]. Life, 10(4), 48. doi: 10.3390/life10040048
Ladyman, S. R., Hackwell, E. C. R., & Brown, R. S. E. (2020). The role of prolactin in co-ordinating fertility and metabolic adaptations during reproduction. Neuropharmacology, 167, 107911. doi: 10.1016/j.neuropharm.2019.107911
Le Tissier, P. R., & Grattan, D. R. (2020). Growth hormone and prolactin: So much still to learn. Journal of Neuroendocrinology, 32(11), e12909. doi: 10.1111/jne.12909
Lemaître, J.-F., Garratt, M., & Gaillard, J.-M. (2020). Going beyond lifespan in comparative biology of aging. Advances in Geriatric Medicine & Research, 2(2), e200011. doi: 10.20900/agmr20200011
Lopez-Vicchi, F., De Winne, C., Brie, B., Sorianello, E., Ladyman, S. R., & Becu-Villalobos, D. (2020). Metabolic functions of prolactin: Physiological and pathological aspects. Journal of Neuroendocrinology, 32, e12888. doi: 10.1111/jne.12888
McCartney, C. R., & Campbell, R. E. (2020). Abnormal GnRH pulsatility in polycystic ovary syndrome: Recent insights. Current Opinion in Endocrine & Metabolic Research, 12, 78-84. doi: 10.1016/j.coemr.2020.04.005
Phillipps, H. R., Yip, S. H., & Grattan, D. R. (2020). Patterns of prolactin secretion. Molecular & Cellular Endocrinology, 502, 110679. doi: 10.1016/j.mce.2019.110679