Desroziers Laboratory

2023

Journal - Research Article

Donaldson, N. M., Prescott, M., Ruddenklau, A., Campbell, R. E., & Desroziers, E. (2023). Maternal androgen excess significantly impairs sexual behavior in male and female mouse offspring: Perspective for a biological origin of sexual dysfunction in PCOS. Frontiers in Endocrinology, 14, 1116482. doi: 10.3389/fendo.2023.1116482

Journal - Research Other

Sati, A., Desroziers, E., & Campbell, R. E. (2023). Microglia: Sculptors of the polycystic ovary syndrome (PCOS)-like brain? Reproduction. Advance online publication. doi: 10.1530/rep-22-0343

2022

Journal - Research Article

Khant Aung, Z., Masih, R. R., Desroziers, E., Campbell, R. E., & Brown, R. S. E. (2022). Enhanced pup retrieval behaviour in a mouse model of polycystic ovary syndrome. Journal of Neuroendocrinology, 34, e13206. doi: 10.1111/jne.13206

Journal - Research Other

Desroziers, E. (2022). Unusual suspects: Glial cells in fertility regulation and their suspected role in polycystic ovary syndrome. Journal of Neuroendocrinology, 34, e13136. doi: 10.1111/jne.13136

Conference Contribution - Verbal presentation and other Conference outputs

Campbell, R. E., Sati, A., Coyle, C., Prescott, M., Jasoni, C. L., & Desroziers, E. (2022, August). How androgen excess shapes the polycystic ovary syndrome (PCOS)-like brain. Verbal presentation at the Metabolic & Cardiovascular Disease Satellite Meeting: Queenstown Research Week, Queenstown, New Zealand.

2021

Journal - Research Article

Sati, A., Prescott, M., Holland, S., Jasoni, C. L., Desroziers, E., & Campbell, R. E. (2021). Morphological evidence indicate a role for microglia in shaping the polycystic ovary syndrome (PCOS)-like brain. Journal of Neuroendocrinology, 33, e12999. doi: 10.1111/jne.12999

Elenis, E., Desroziers, E., Persson, S., Sundström Poromaa, I., & Campbell, R. E. (2021). Early initiation of anti-androgen treatment is associated with increased probability of spontaneous conception leading to childbirth in women with polycystic ovary syndrome: A population-based multiregistry cohort study in Sweden. Human Reproduction, 36(5), 1427-1435. doi: 10.1093/humrep/deaa357

Conference Contribution - Published proceedings: Abstract

Sati, A., Prescott, M., Jasoni, C. L., Desroziers, E., & Campbell, R. E. (2021). The role of microglia in the polycystic ovary syndrome (PCOS)-like brain. Journal of the Endocrine Society, 5(Suppl. 1), (pp. A556). doi: 10.1210/jendso/bvab048.1133

2020

Journal - Research Other

Winship, A., Donoghue, J., Houston, B. J., Martin, J. H., Lord, T., Adwal, A., … Desroziers, E., … Bromfield, E. G. (2020). Reproductive health research in Australia and New Zealand: Highlights from the Annual Meeting of the Society for Reproductive Biology, 2019. Reproduction, Fertility & Development, 32(7), 637-647. doi: 10.1071/RD19449

2019

Journal - Research Article

Silva, M. S. B., Desroziers, E., Hessler, S., Prescott, M., Coyle, C., Herbison, A. E., & Campbell, R. E. (2019). Activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion and reproductive dysfunction: Implications for polycystic ovary syndrome. EBioMedicine, 44, 582-596. doi: 10.1016/j.ebiom.2019.05.065

Conference Contribution - Published proceedings: Abstract

Holland, S., Prescott, M., Desroziers, E., & Campbell, R. (2019). Elucidating the effect of prenatal androgen excess on male reproductive function and metabolism. New Zealand Medical Journal, 132(1499), (pp. 88). Retrieved from https://www.nzma.org.nz/journal

Conference Contribution - Poster Presentation (not in published proceedings)

Sati, A., Prescott, M., Desroziers, E., Jasoni, C. L., & Campbell, R. E. (2019, September). The impact of prenatal androgen excess on microglia in the female mouse brain. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Desroziers, E., Prescott, M., & Campbell, R. E. (2019, August-September). Prenatal androgen excess impairs sexual behavior in adult female mice: Perspective on sexual dysfunction in PCOS. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Desroziers, E., Hessler, S., Prescott, M., Coyle, C., Herbison, A. E., & Campbell, R. E. (2019, August-September). Chemogenetic activation of arcuate GABA neurons lead to reproductive dysfunction in female: Implication for polycystic ovary syndrome. Verbal presentation at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2018

Journal - Research Article

Moore, A. M., Prescott, M., Czieselsky, K., Desroziers, E., Yip, S. H., Campbell, R. E., & Herbison, A. E. (2018). Synaptic innervation of the GnRH neuron distal dendron in female mice. Endocrinology, 159(9), 3200-3208. doi: 10.1210/en.2018-00505

Hellier, V., Brock, O., Candlish, M., Desroziers, E., Aoki, M., Mayer, C., Piet, R., Herbison, A., … Bakker, J. (2018). Female sexual behavior in mice is controlled by kisspeptin neurons. Nature Communications, 9, 400. doi: 10.1038/s41467-017-02797-2

Conference Contribution - Published proceedings: Abstract

Desroziers, E., Prescott, M., & Campbell, R. E. (2018). Impaired sexual behaviour in a mouse model of PCOS. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 288-289). Retrieved from http://www.icn2018.org/

Desroziers, E., Coutinho, E., Prescott, M., Silva, M., Holland, S., & Campbell, R. E. (2018). The impact of chronic activation of arcuate GABA neurons on fertility. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 246). Retrieved from http://www.icn2018.org/

Coutinho, E., Prescott, M., Desroziers, E., Hessler, S., & Campbell, R. E. (2018). Activation of ARN AgRP/NPY neurons slows LH pulsality in control and PCOS mice. Proceedings of the 9th International Congress of Neuroendocrinology (ICN). (pp. 133). Retrieved from http://www.icn2018.org/

Conference Contribution - Poster Presentation (not in published proceedings)

Coutinho, E. A., Prescott, M., Desroziers, E., Marshall, C., Hessler, S., Herbison, A. E., & Campbell, R. E. (2018, August). Role of arcuate nucleus AgRP/NPY neurons in LH secretion and fertility. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Holland, S., Prescott, M., Desroziers, E., & Campbell, R. E. (2018, August). Elucidating the effect of prenatal androgen excess on male reproductive function metabolism. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Desroziers, E., Prescott, M., & Campbell, R. E. (2018, August). Impaired sexual behaviour in a mouse model of PCOS. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Conference Contribution - Verbal presentation and other Conference outputs

Ross, P. G., Desroziers, E., Prescott, M., Silva, M., & Campbell, R. E. (2018, August). Long term effects of androgen receptor blockade in a mouse model of polycystic ovarian syndrome. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Ruddenklau, A. L., Desroziers, E., Prescott, M., Silva, M. S., & Campbell, R. E. (2018, August). Can androgen receptor blockade restore progesterone sensitivity in a mouse model of polycystic ovary syndrome (PCOS)? Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Desroziers, E., Coutinho, E., Prescott, M., Silva, M., Holland, S., & Campbell, R. E. (2018, August). The impact of chronic activation of arcuate GABA neurons on fertility. Verbal presentation at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Other Research Output

Desroziers, E. (2018, September). Role of arcurate GABA neurons in fertility. Department of Physiology, University of Otago, Dunedin, New Zealand. [Department Seminar].

2017

Journal - Research Article

Marshall, C. J., Desroziers, E., McLennan, T., & Campbell, R. E. (2017). Defining subpopulations of arcuate nucleus GABA neurons in male, female, and prenatally androgenized female mice. Neuroendocrinology, 105(2), 157-169. doi: 10.1159/000452105

Desroziers, E., Brock, O., & Bakker, J. (2017). Potential contribution of progesterone receptors to the development of sexual behavior in male and female mice. Hormones & Behavior, 90, 31-38. doi: 10.1016/j.yhbeh.2016.05.008

Conference Contribution - Published proceedings: Abstract

Coutinho, E. A., Desroziers, E., Prescott, M., & Campbell, R. E. (2017). Chemogenetic activation of arcuate neuropeptide Y neurons alters luteinising hormone secretion in mice. Endocrine Reviews, 38(3, Suppl.), SAT 447. [Abstract]

Conference Contribution - Poster Presentation (not in published proceedings)

Coutinho, E. A., Desroziers, E., Prescott, M., & Campbell, R. E. (2017, September). Activation of arcuate neuropeptide Y neurons alters luteinising hormone secretion in mice. Poster session presented at the Medical Sciences Congress (MedSci), Queenstown, New Zealand.

Prescott, M., Czieselsky, K., Desroziers, E., Herbison, A. E., & Campbell, R. E. (2017, September). Finding CLARITY: Visualising the gonadotrophin-releasing hormone neuron. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Holland, S. L., Desroziers, E., Silva, M., Prescott, M., & Campbell, R. E. (2017, September). Investigating the role of microglia in polycystic ovary syndrome (PCOS). Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Desroziers, E., Coutinho, E., Prescott, M., Silva, S., Holland, S., & Campbell, R. E. (2017, September). Deciphering the role of arcuate GABA neurons in fertility regulation with chemogenetic tools in vivo. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

Coutinho, E. A., Desroziers, E., Prescott, M., & Campbell, R. E. (2017, September). Activations of arcuate neuropeptide Y neurons alters luteinising hormone secretion in mice. Poster session presented at the Queenstown Molecular Biology (QMB) Meetings, Queenstown, New Zealand.

2016

Journal - Research Article

Pinet-Charvet, C., Geller, S., Desroziers, E., Ottogalli, M., Lomet, D., Georgelin, C., … Duittoz, A. (2016). GnRH episodic secretion is altered by pharmacological blockade of gap junctions: Possible involvement of glial cells. Endocrinology, 157(1), 304-322. doi: 10.1210/en.2015-1437

Conference Contribution - Published proceedings: Abstract

Marshall, C. J., Desroziers, E., & Campbell, R. E. (2016). Defining subpopulations of arcuate nucleus GABA neurons in male, female and prenatally androgenized female mice: A role for GABAergic NPY neurons in regulating fertility? Proceedings of the Society for Neuroscience 46th Annual Meeting. 339.02/TT8. SfN. Retrieved from https://www.sfn.org/

Conference Contribution - Poster Presentation (not in published proceedings)

Desroziers, E., Marshall, C. J., Prescott, M., & Campbell, R. E. (2016, August). Sexually differentiated co-expression of neuronal nitric oxide synthase (nNOS) in arcuate nucleus GABA neurons. Poster session presented at the Medical Sciences Congress (MedSci), Nelson, New Zealand.

2013

Journal - Research Article

Franceschini, I., & Desroziers, E. (2013). Development and aging of the kisspeptin-GPR54 system in the mammalian brain: What are the impacts on female reproductive function? Frontiers in Endocrinology, 4, 22. doi: 10.3389/fendo.2013.00022

Overgaard, A., Tena-Sempere, M., Franceschini, I., Desroziers, E., Simonneaux, V., & Mikkelsen, J. D. (2013). Comparative analysis of kisspeptin-immunoreactivity reveals genuine differences in the hypothalamic Kiss1 systems between rats and mice. Peptides, 45, 85-90. doi: 10.1016/j.peptides.2013.04.013

Franceschini, I., Yeo, S. H., Beltramo, M., Desroziers, E., Okamura, H., Herbison, A. E., & Caraty, A. (2013). Immunohistochemical evidence for the presence of various kisspeptin isoforms in the mammalian brain. Journal of Neuroendocrinology, 25(9), 839-851. doi: 10.1111/jne.12069

2012

Journal - Research Article

Desroziers, E., Mikkelsen, J. D., Duittoz, A., & Franceschini, I. (2012). Kisspeptin-immunoreactivity changes in a sex- and hypothalamic-region-specific manner across rat postnatal development. Journal of Neuroendocrinology, 24(8), 1154-1165. doi: 10.1111/j.1365-2826.2012.02317.x

Desroziers, E., Droguerre, M., Bentsen, A. H., Robert, V., Mikkelsen, J. D., Caraty, A., … Franceschini, I. (2012). Embryonic development of kisspeptin neurones in rat. Journal of Neuroendocrinology, 24(10), 1284-1295. doi: 10.1111/j.1365-2826.2012.02333.x

2010

Journal - Research Article

Desroziers, E., Mikkelsen, J., Simonneaux, V., Keller, M., Tillet, Y., Caraty, A., & Franceschini, I. (2010). Mapping of kisspeptin fibres in the brain of the pro-oestrous rat. Journal of Neuroendocrinology, 22(10), 1101-1112. doi: 10.1111/j.1365-2826.2010.02053.x

Franceschini, I., Desroziers, E., Caraty, A., & Duittoz, A. (2010). The intimate relationship of gonadotropin-releasing hormone neurons with the polysialyated neural cell adhesion molecule revisited across development and adult plasticity. European Journal of Neuroscience, 32(12), 2031-2041. doi: 10.1111/j.1460-9568.2010.07517.x