Dr Olivia Harrison, Our People, Department of Psychology

Email olivia.harrison@otago.ac.nz
Tel +64 3 479 8818

My research focuses on mental health and its relationship to interoception (how we perceive our body).

I use neuroimaging and computational models to better understand how the brain perceives and learns about changes in the body, with a particular focus on breathing. My work also aims to understand how currently available treatments such as anxiolytics and exercise can improve conditions such as anxiety and depression.

Publications

Harrison, O. K., & Pink, A. (2024). Interoception and physical health. In J. Murphy & R. Brewer (Eds.), Interoception: A comprehensive guide. (pp. 227-264). Cham, Switzerland: Springer Nature. doi: 10.1007/978-3-031-68521-7_8 Chapter in Book - Research

Chin, P., Gorman, F., Beck, F., Russell, B. R., Stephan, K. E., & Harrison, O. K. (2024). A systematic review of brief respiratory, embodiment, cognitive and mindfulness interventions to reduce state anxiety. Frontiers in Psychology. Advance online publication. doi: 10.3389/fpsyg.2024.1412928 Journal - Research Other

Brand, K., Wise, T., Hess, A. J., Russell, B. R., Stephan, K. E., & Harrison, O. K. (2024). Incorporating uncertainty within dynamic interoceptive learning. Frontiers in Psychology, 15, 1254564. doi: 10.3389/fpsyg.2024.1254564 Journal - Research Article

Cawood, T., Russell, B., Harrison, O., & Linscott, R. (2023). Altered brain morphology and chemistry correlates with augmented drug therapy for treatment-resistant schizophrenia. Proceedings of the Psycolloquy Symposium. (pp. 33). Dunedin, New Zealand: Department of Psychology, University of Otago. Retrieved from https://www.otago.ac.nz/psychology/research/otago059081.html Conference Contribution - Published proceedings: Abstract

Kemp, A., Harrison, O., Russell, B., & Glue, P. (2023). Using neuroimaging to investigate functional connectivity alterations associated with anxiety. Proceedings of the Psycolloquy Symposium. (pp. 29). Dunedin, New Zealand: Department of Psychology, University of Otago. Retrieved from https://www.otago.ac.nz/psychology/research/otago059081.html Conference Contribution - Published proceedings: Abstract

2024

Chapter in Book - Research

Journal - Research Article

Journal - Research Other

2023

Chapter in Book - Research

Harrison, O. K., Brooks, J. C. W., & Clare, S. (2023). Brainstem imaging. In K. Markenroth Bloch, M. Guye & B. A. Poser (Eds.), Ultra-high field neuro MRI (Vol. 10). (pp. 287-299). Cambridge, MA: Academic Press. doi: 10.1016/B978-0-323-99898-7.00017-1

Journal - Research Article

Finnegan, S. L., Harrison, O. K., Booth, S., Dennis, A., Ezra, M., Harmer, C. J., … Pattinson, K. T. S. (2023). The effect of D-cycloserine on brain processing of breathlessness over pulmonary rehabilitation: An experimental medicine study. ERJ Open Research, 9(2), 00479-2022. doi: 10.1183/23120541.00479-2022

Journal - Research Other

Connor, M., Hargreaves, E. A., Scanlon, O. K., & Harrison, O. K. (2023). The effect of acute exercise on state anxiety: A systematic review. Sports, 11, 145. doi: 10.3390/sports11080145

Conference Contribution - Published proceedings: Abstract

2022

Journal - Research Article

Harrison, O., Russell, B. R., & Pattinson, K. T. S. (2022). Perceptual and ventilatory responses to hypercapnia in athletes and sedentary individuals. Frontiers in Physiology, 13, 820307. doi: 10.3389/fphys.2022.820307

Nikolova, N., Harrison, O., Toohey, S., Brændholt, M., Legrand, N., Correa, C., … Allen, M. (2022). The respiratory resistance sensitivity task: An automated method for quantifying respiratory interoception and metacognition. Biological Psychology, 170, 103325. doi: 10.1016/j.biopsycho.2022.108325

Talks, B. J., Campbell, C., Larcombe, S. J., Marlow, L., Finnegan, S. L., Lewis, C. T., … Harrison, O. K., & Pattinson, K. T. S. (2022). Baseline psychological traits contribute to Lake Louise Acute Mountain Sickness Score at high altitude. High Altitude Medicine & Biology, 23(1), 69-77. doi: 10.1089/ham.2021.0073

Conference Contribution - Published proceedings: Abstract

Scanlon, O., Hargreaves, E., Connor, M., & Harrison, O. K. (2022). Effect of acute exercise on the state anxiety and autonomic regulation of moderately-anxious, sedentary individuals. Journal of Sport & Exercise Science, 6(4), (pp. 40-41). doi: 10.36905/jses.2022.04.01

Kemp, A., Pattinson, K., Glue, P., Russell, B., & Harrison, O. (2022). Assessing the relationship between sub-clinical anxiety and resting state functional connectivity. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 86). Retrieved from https://www.queenstownresearchweek.org

Cawood, S., Neehoff, S., Glue, P., Williams, J., Ryan, M., Russell, B., & Harrison, O. (2022). Investigating the relationship between microRNA expression, brain structure and biochemistry in anxiety disorders and their potential treatment with ketamine. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 82). Retrieved from https://www.queenstownresearchweek.org

Dawson, C., Schoss, S., Russell, B. R., Sellbom, M., & Harrison, O. (2022). Assessing the relationship between intrinsic motivations, personality traits and mental health. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 77). Retrieved from https://www.queenstownresearchweek.org

Brand, K., Wise, T., Russell, B., & Harrison, O. (2022). Developing models of dynamic interoceptive learning. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 63). Retrieved from https://www.queenstownresearchweek.org

Harrison, O. K., Köchli, L., Marino, S., Marlow, L., Finnegan, S. L., Ainsworth, B., Russell, B. R., … Stephan, K. E. (2022). Anxiety is associated with interoceptive insight deficits in women but not men. In K. Horne (Ed.), Proceedings of the 38th International Australasian Winter Conference on Brain Research (AWCBR). (pp. 39). Retrieved from https://www.queenstownresearchweek.org

Connor, M., Scanlon, O. K., Hargreaves, E. A., & Harrison, O. K. (2022). Resistance and aerobic exercise of moderate or self-selected intensity is effective in reducing anxiety. New Zealand Medical Journal, 135(1557), (pp. 105). Retrieved from https://journal.nzma.org.nz/

Conference Contribution - Verbal presentation and other Conference outputs

Kemp, A., Pattinson, K., Glue, P., Russell, B., & Harrison, O. (2022, September). Assessing the relationship between sub-clinical anxiety and resting state functional connectivity. Verbal presentation at the Postgraduate & Early Career Researchers Committee (PERC) & Division of Health Sciences Early & Mid-Career Researcher (EMCR) Joint Research Symposium, Dunedin, New Zealand.

Harrison, O. (2022, July). Anxiety is only associated with deficits in interoceptive insight in women and not men. Verbal presentation at the Brain Health Research Centre (BHRC) Hui ā Tau Annual Conference: Te Haerenga o te tangata: Lifespan, Dunedin, New Zealand.

Other Research Output

Harrison, O. (2022, March). Breathing and anxiety: Understanding the miscommunication between the brain and body, and how best to treat it. March with Otago seminar series, University of Otago, [Online]. Retrieved from https://www.youtube.com/watch?v=kb2DGLZRdZ4

2021

Journal - Research Article

Harrison, O. K., Hayen, A., Wager, T. D., & Pattinson, K. T. S. (2021). Investigating the specificity of the neurologic pain signature against breathlessness and finger opposition. Pain, 162(12), 2933-2944. doi: 10.1097/j.pain.0000000000002327

Harrison, O. K., Köchli, L., Marino, S., Luechinger, R., Hennel, F., Brand, K., … Stephan, K. E. (2021). Interoception of breathing and its relationship with anxiety. Neuron, 109, 4080-4093. doi: 10.1016/ j.neuron.2021.09.045

Harrison, O. K., Garfinkel, S. N., Marlow, L., Finnegan, S. L., Marino, S., Köchli, L., … Fleming, S. M. (2021). The filter detection task for measurement of breathing-related interoception and metacognition. Biological Psychology, 165, 108185. doi: 10.1016/j.biopsycho.2021.108185

Harrison, O. K., Guell, X., Klein-Flügge, M. C., & Barry, R. L. (2021). Structural and resting state functional connectivity beyond the cortex. NeuroImage, 240, 118379. doi: 10.1016/j.neuroimage.2021.118379

Finnegan, S. L., Harrison, O. K., Harmer, C. J., Herigstad, M., Rahman, N. M., Reinecke, A., & Pattinson, K. T. S. (2021). Breathlessness in COPD: Linking symptom clusters with brain activity. European Respiratory Journal, 58, 2004099. doi: 10.1183/13993003.04099-2020

Journal - Research Other

Harrison, O. K., Marlow, L., Finnegan, S. L., Ainsworth, B., & Pattinson, K. T. S. (2021). Dissociating breathlessness symptoms from mood in asthma. Biological Psychology, 165, 108193. doi: 10.1016/j.biopsycho.2021.108193

Frässle, S., Aponte, E. A., Bollmann, S., Brodersen, K. H., Do, C. T., Harrison, O. K., … Stephan, K. E. (2021). TAPAS: An open-source software package for Translational Neuromodeling and Computational Psychiatry. Frontiers in Psychiatry, 12, 680811. doi: 10.3389/fpsyt.2021.680811

Conference Contribution - Published proceedings: Abstract

Kwon, M., van 't Hof, S., Botvinik-Nezer, R., Amini, M., Bango, C., Hunt, B., … Harrison, O., … Wager, T. D. (2021). The Affective Neuroimaging Collaboratory (ANiC) Towards a better understanding of the neural architecture of affective processes. Proceedings of the Neuroscience (SfN) Annual Meeting. P690.09. Retrieved from https://www.sfn.org/meetings/neuroscience-2021

Conference Contribution - Verbal presentation and other Conference outputs

Harrison, O. (2021, December). Breathing and pain in the brain. Verbal presentation at the Pain@Otago Research Symposium, [Online].

2020

Journal - Research Other

Rieger, S. W., Stephan, K. E., & Harrison, O. K. (2020). Remote, automated, and MRI-compatible administration of interoceptive inspiratory resistive loading. Frontiers in Human Neuroscience, 14, 161. doi: 10.3389/fnhum.2020.00161

Conference Contribution - Poster Presentation (not in published proceedings)

Faull, O., Rieger, S., Marino, S., Nanz, L., Luechinger, R., Hennel, F., … Stephan, K. E. (2020, June-July). Cortical processing of interoceptive prediction errors using inspiratory resistive loads. Poster session presented at the Organization for Human Brain Mapping (OHBM) 26th Annual Meeting, [Online].

Finnegan, S., Faull, O., Harmer, C., Herigstad, M., Rahman, N., Reinecke, A., & Pattinson, K. (2020, June-July). Neuropsychological models of breathlessness. Poster session presented at the Organization for Human Brain Mapping (OHBM) 26th Annual Meeting, [Online].

Working Paper; Discussion Paper; Technical Report

Harrison, O. K., Hayen, A., Wager, T. D., & Pattinson, K. T. S. (2020). Pain and breathlessness: Salient, somatosensory and similar, but not the same. bioRxiv. doi: 10.1101/2020.05.04.076174

Harrison, O. K., Garfinkel, S. N., Marlow, L., Finnegan, S., Marino, S., Nanz, L., … Fleming, S. T. (2020). The Filter Detection Task for measurement of breathing-related interoception and metacognition. bioRxiv. doi: 10.1101/2020.06.29.176941

Harrison, O. K., Marlow, L., Finnegan, S., Ainsworth, B., & Pattinson, K. T. S. (2020). Dissociating breathlessness symptoms from mood in asthma. bioRxiv. doi: 10.1101/2020.07.15.204289

2019

Journal - Research Article

Dearlove, D. J., Faull, O. K., Rolls, E., Clarke, K., & Cox, P. J. (2019). Nutritional ketoacidosis during incremental exercise in healthy athletes. Frontiers in Physiology, 10, 290. doi: 10.3389/fphys.2019.00290

Faull, O. K., Dearlove, D. J., Clarke, K., & Cox, P. J. (2019). Beyond RPE: The perception of exercise under normal and ketotic conditions. Frontiers in Physiology, 10, 229. doi: 10.3389/fphys.2019.00229

Journal - Research Other

Faull, O. K., Subramanian, H. H., Ezra, M., & Pattinson, K. T. S. (2019). The midbrain periaqueductal gray as an integrative and interoceptive neural structure for breathing. Neuroscience & Biobehavioral Reviews, 98, 135-144. doi: 10.1016/j.neubiorev.2018.12.020

Dearlove, D. J., Faull, O. K., & Clarke, K. (2019). Context is key: Exogenous ketosis and athletic performance. Current Opinion in Physiology, 10, 81-89. doi: 10.1016/j.cophys.2019.04.010

Marlow, L. L., Faull, O. K., Finnegan, S. L., & Pattinson, K. T. S. (2019). Breathlessness and the brain: The role of expectation. Current Opinion in Supportive & Palliative Care, 13(3), 200-210. doi: 10.1097/SPC.0000000000000441

Abdallah, S. J., Faull, O. K., Wanigasekera, V., Finnegan, S. L., Jensen, D., & Pattinson, K. T. S. (2019). Opioids for breathlessness: Psychological and neural factors influencing response variability. European Respiratory Journal, 54(3), 1900275. doi: 10.1183/13993003.00275-2019

Working Paper; Discussion Paper; Technical Report

Finnegan, S. L., Faull, O. K., Harmer, C. J., Herigstad, M., Rahman, N. M., Reinecke, A., & Pattinson, K. T. S. (2019). Neuropsychological stratification of chronic obstructive pulmonary disease: Building affect into clinically relevant neuro-biomarkers of breathlessness. medRxiv. doi: 10.1101/19006684

Rieger, S. W., Stephan, K. E., & Faull, O. K. (2019). Tools and resources: Remote, automated and MRI-compatible administration of interoceptive inspiratory resistive loading. bioRxiv. doi: 10.1101/2019.12.09.869511

2018

Journal - Research Article

Faull, O. K., Cox, P. J., & Pattinson, K. T. S. (2018). Cortical processing of breathing perceptions in the athletic brain. NeuroImage, 179, 92-101. doi: 10.1016/j.neuroimage.2018.06.021

Journal - Research Other

Faull, O. K., Marlow, L., Finnegan, S. L., & Pattinson, K. T. S. (2018). Chronic breathlessness: Re-thinking the symptom. European Respiratory Journal, 51, 1702238. doi: 10.1183/13993003.02238-2017

2017

Journal - Research Article

Faull, O. K., & Pattinson, K. T. S. (2017). The cortical connectivity of the periaqueductal gray and the conditioned response to the threat of breathlessness. eLIFE, 6, e21749. doi: 10.7554/eLife.21749

Herigstad, M., Faull, O. K., Hayen, A., Evans, E., Hardinge, F. M., Wiech, K., & Pattinson, K. T. S. (2017). Treating breathlessness via the brain: Changes in brain activity over a course of pulmonary rehabilitation. European Respiratory Journal, 50(3), 1701029. doi: 10.1183/13993003.01029-2017

Faull, O. K., Hayen, A., & Pattinson, K. T. S. (2017). Breathlessness and the body: Neuroimaging clues for the inferential leap. Cortex, 95, 211-221. doi: 10.1016/j.cortex.2017.07.019

Hayen, A., Wanigasekera, V., Faull, O. K., Campbell, S. F., Garry, P. S., Raby, S. J. M., … Pattinson, K. T. S. (2017). Opioid suppression of conditioned anticipatory brain responses to breathlessness. NeuroImage, 150, 383-394. doi: 10.1016/j.neuroimage.2017.01.005

Stubbs, B. J., Cox, P. J., Evans, R. D., Santer, P., Miller, J. J., Faull, O. K., … Clarke, K. (2017). On the metabolism of exogenous ketones in humans. Frontiers in Physiology, 8, 848. doi: 10.3389/fphys.2017.00848

Conference Contribution - Published proceedings: Abstract

Faull, O., Cox, P., & Pattinson, K. (2017). The efficient athlete brain: Cortical processing of breathlessness. Brain & Neuroscience Advances, 1, P-M032. doi: 10.1177/2398212817705279

Conference Contribution - Poster Presentation (not in published proceedings)

Faull, O., & Pattinson, K. (2017, June). The cortical connectivity of the periaqueductal gray and the conditioned threat of breathlessness. Poster session presented at the Organization for Human Brain Mapping (OHBM) 23rd Annual Meeting, Vancouver, Canada.

Working Paper; Discussion Paper; Technical Report

Faull, O. K., Cox, P. J., & Pattinson, K. T. S. (2017). Cortical processing of breathlessness in the athletic brain. bioRxiv. doi: 10.1101/174052

2016

Journal - Research Article

Faull, O. K., Jenkinson, M., Ezra, M., & Pattinson, K. T. S. (2016). Conditioned respiratory threat in the subdivisions of the human periaqueductal gray. eLIFE, 5, e12047. doi: 10.7554/eLife.12047.001

Faull, O. K., Cox, P. J., & Pattinson, K. T. S. (2016). Psychophysical differences in ventilatory awareness and breathlessness between athletes and sedentary individuals. Frontiers in Physiology, 7, 231. doi: 10.3389/fphys.2016.00231

Conference Contribution - Published proceedings: Abstract

Cox, P. J., Faull, O., Ashmore, T., Stubbs, B. J., Dearlove, D., Murray, A., … Clarke, K. (2016). Nutritional ketosis regulates BCAA metabolism in exercise. Proceedings of The Physiological Society, 37, PCA183. Retrieved from http://www.physoc.org

Cox, P. J., Cvetko, F., Faull, O., Kirk, T., Stubbs, B. J., & Clarke, K. (2016). Nutritional ketosis: A metabolic replacement for glucose in exercise performance? Proceedings of The Physiological Society, 37, PCA182. Retrieved from http://www.physoc.org

Stubbs, B. J., Cox, P. J., Faull, O., Kirk, T., Willerton, K., & Clarke, K. (2016). The role of muscle fibre type in skeletal muscle substrate oxidation during nutritional ketosis. Proceedings of The Physiological Society, 37, PCA184. Retrieved from http://www.physoc.org

2015

Journal - Research Article

Faull, O. K., Robertson, J., Thomas, O., Bradwell, A. R., Antoniades, C. A., & Pattinson, K. T. S. (2015). The effect of acetazolamide on saccadic latency at 3459 meters. Wilderness & Environmental Medicine, 26(1), 72-77. doi: 10.1016/j.wem.2014.08.017

Faull, O. K., Jenkinson, M., Clare, S., & Pattinson, K. T. S. (2015). Functional subdivision of the human periaqueductal grey in respiratory control using 7 tesla fMRI. NeuroImage, 113, 356-364. doi: 10.1016/j.neuroimage.2015.02.026

Ezra, M., Faull, O. K., Jbabdi, S., & Pattinson, K. T. (2015). Connectivity-based segmentation of the periaqueductal gray matter in human with brainstem optimized diffusion MRI. Human Brain Mapping, 36(9), 3459-3471. doi: 10.1002/hbm.22855

Faull, O. K., Cotter, J. D., & Lucas, S. J. E. (2015). Cerebrovascular responses during rowing: Do circadian rhythms explain morning and afternoon performance differences? Scandinavian Journal of Medicine & Science in Sports, 25(4), 467-475. doi: 10.1111/sms.12273

Conference Contribution - Poster Presentation (not in published proceedings)

Faull, O. K., Ezra, M., & Pattinson, K. T. S. (2015, June). The role of the ventrolateral periqueductal gray in conditioned responses to breathlessness. Poster session presented at the Organization for Human Brain Mapping (OHBM) 21st Annual Meeting, Honolulu, HI.

Awarded Doctoral Degree

Faull, O. (2015). The role of the periaqueductal gray in respiratory control and breathlessness (DPhil). University of Oxford, Oxford, UK. Retrieved from https://ora.ox.ac.uk/objects/uuid:8be9a788-57c7-4323-8052-c849bc9a8eb6

2014

Conference Contribution - Published proceedings: Abstract

Ezra, M., Faull, O. K., Jbabdi, S., & Pattinson, K. T. S. (2014). Connectivity based segmentation of the periaqueductal grey matter in humans with diffusion tensor imaging. Proceedings of the International Society of Magnetic Resonancing & Medicine, 22, 0052. Retrieved from https://www.semanticscholar.org

2013

Journal - Research Other

Brooks, J. C. W., Faull, O. K., Pattinson, K. T. S., & Jenkinson, M. (2013). Physiological noise in brainstem fMRI. Frontiers in Human Neuroscience, 7, 623. doi: 10.3389/fnhum.2013.00623