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Ana Holley image

PhD (VUW), MBmedSc (VUW), BSc (Massey)

Background

I completed both my Masters and PhD in Biomedical Science through Victoria University of Wellington, before undertaking a post-doctoral fellowship here at the University of Otago, Wellington campus.  The main focus of my research has always been centred in developing better scoring tools for stratifying risk in cardiac disease.  Identifying patients who are at increased risk of adverse clinical events means patient management can be personalised in order to improve patient outcomes.

My current research uses a mixture of molecular and genetic techniques in order to identify biomarkers relating to inflammation, small RNA molecules and genetic variants measured in patients who have suffered a heart attack.  My research is done through Wellington Cardiovascular Research Group, and we work closely with cardiologists from Wellington Hospital in how we can best apply biomedical information so patients can benefit from better risk assessment models.

There are several postgraduate research opportunities (Honours, Masters, PhD) available in this field through the Wellington Cardiovascular Research Group.

Contact details

Department of Surgery & Anaesthesia
University of Otago, Wellington
PO Box 7343
Wellington South

Email ana.holley@otago.ac.nz

Dr Holley's Health Sciences database profile page

Current roles

  • Lecturer, Surgery and Anaesthesia
  • Scientist, Wellington Cardiovascular Research Group
  • Postgraduate Biomedical Seminar Series Co-ordinator

Research expertise

  • Translational Cardiovascular Medicine

Publications

Whitfield, P. L., Hall, R. M., Théaude, L., Sixtus, R. P., Kanaan, R., Holley, A. S., … Weatherall, M., … Krebs, J. D. (2024). A very-low-calorie diet (VLCD) intervention for the management of prediabetes and early Type 2 diabetes mellitus in a multi-ethnic cohort in Aotearoa New Zealand: The PROGRESS NZ feasibility study. Asia Pacific Journal of Clinical Nutrition, 33(2), 200-212. doi: 10.6133/apjcn.202406_33(2).0007 Journal - Research Article

Yiu, J. Y. T., Hally, K. E., Larsen, P. D., & Holley, A. S. (2023). Neutrophil-enriched biomarkers and long-term prognosis in acute coronary syndrome: A systematic review and meta-analysis. Journal of Cardiovascular Translational Research. Advance online publication. doi: 10.1007/s12265-023-10425-2 Journal - Research Article

Holley, A., Yiu, J., Hally, K., & Larsen, P. (2023). Neutrophil biomarkers and long-term prognosis in acute coronary syndrome: A systematic review and meta-analysis. Heart, Lung & Circulation, 32(Suppl. 3), 678. doi: 10.1016/j.hlc.2023.06.582 Conference Contribution - Published proceedings: Abstract

Blackshaw, C., Hally, K., Harding, S., Fairley, S., Larsen, P., & Holley, A. (2023). Gender differences in demographics, management, and clinical outcomes in AMI patients. Heart, Lung & Circulation, 32(Suppl. 3), 386. doi: 10.1016/j.hlc.2023.06.382 Conference Contribution - Published proceedings: Abstract

Yiu, J. Y. T., Hally, K. E., Larsen, P. D., & Holley, A. S. (2023). Increased levels of low density neutrophils (LDNs) in myocardial infarction. Acta Cardiologica, 78(1), 47-54. doi: 10.1080/00015385.2021.2015145 Journal - Research Article

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