Red X iconGreen tick iconYellow tick icon

Further publications from researchers in the Otago Zebrafish Facility are available under the researchers' pages.

201120102009200820072006

2011

Mönnich M, Kuriger Z, Print CG, Horsfield JA (2011) A Zebrafish Model of Roberts Syndrome Reveals That Esco2 Depletion Interferes with Development by Disrupting the Cell Cycle. PLoS ONE 6(5): e20051. doi:10.1371/journal.pone.0020051

Simpson MA, Irving MD, Asilmaz E, Gray MJ, Dafou D, Elmslie F, Mansour S, Holder SE, Brain CE, Burton BK, Kim KH, Aftimos S, Stewart H, Kim CA, Holder-Espinasse M, Robertson SP, Drake WM, Trembath RC (2011) Mutations in NOTCH2 cause Hajdu Cheney syndrome, a disorder of severe and progressive bone loss. Nature Genetics Mar 6;43(4):303-5.

Sharyn J, Goldstien; Lise Dupont; Frederique Viard; Paul J. Hallas; T. Nishikawa; David R. Schiel; Neil J. Gemmell; John DD Bishop, 2011. Global phylogeography of the widely introduced NW. Pacific ascidian Styela clava. PLoS ONE 6(2): e16755. doi:10.1371/journal.pone.0016755.

Slatter, T.J., Hung, N.A., Campbell, H.C., Rubio, C., Mehta, R., Renshaw, P., Williams, G.,  Wilson, M., Engelmann, A., Jeffs, A., Royds, J.A., Baird, M.A., and Braithwaite, A.W. (2011).   Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform. Blood, In press.

Li, C.G., Nymen, J.E., Braithwaite, A.W. and Eccles, M.R.  (2011). PAX8 promotes tumour cell growth through transcriptionally regulating E2F1 and stabilizing RB protein. Oncogene, accepted.

Nakagawa, S. & Freckelton, R. P. (2011) Model averaging, missing data and multiple imputation: a case study for behavioural ecology. Behavioral Ecology and Sociobiology. 65: 103-116

Nakagawa, S. & Hauber, M. E. (2011) Great challenges with few subjects: statistical strategies for neuroscientists. Neuroscience and Biobehavioral Reviews. 35: 462-473

2010

Rhodes, J. M., Bentley, F. K., Print, C. G., Dorsett, D., Misulovin, Z., Dickinson, E., Crosier, K. E., Crosier, P. S. and Horsfield, J. A. (2010) Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved. Developmental Biology 344: 637-649

Fukuzawa R, HolmanSK, ChowCW, SavarirayanR, Reeve AE, Robertson SP (2010) WTX mutations can occur both early and late in the pathogenesis of Wilms tumour. J Med Genet 47 791-794.

Bell CG, Finer S, Lindgren CM, Wilson GA, Rakyan VK, Teschendorff AE, Akan P, Stupka E, Down TA, Prokopenko I, Morison IM, Mill J, Pidsley R; International Type 2 Diabetes 1q Consortium, Deloukas P, Frayling TM, Hattersley AT, McCarthy MI, Beck S, Hitman GA. Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus. PLoS One. 2010 Nov 18;5(11):e14040.

Weeks RJ, Kees UR, Song S, Morison IM. Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia. Molecular Cancer 2010, 9:163 doi:10.1186/1476-4598-9-163 epub.

Tammy E. Steeves, Richard Maloney, Marie L. Hale, Jason M. Tylianakis and Neil J. Gemmell, 2010. Genetic analyses reveal lack of introgression despite extensive bidirectional hybridization in one of the world's rarest birds. Molecular Ecology 19: 5090-5100. doi: 10.1111/j.1365-294X.2010.04895.x.

Thorsten Horn, Bruce C. Robertson and Neil J. Gemmell, 2010. The use of telomere length in ecology and evolutionary biology. Heredity 105: 497–506.

Emmanuel Buschiazzo and Neil J. Gemmell, 2010. Conservation of human microsatellites across 450 million years of evolution. Genome Biology and Evolution. Vol. 2010:153. doi:10.1093/gbe/evq007.

Cohen, S.B., Ma, W., Valova, V., Harfoot, R., Woolley, A.M., Robinson, P.J., and Braithwaite, A.W. (2010).  Genotoxic stress induced nuclear localization of oncoprotein in the absence of proteolytic processing. Oncogene 129, 403-410.

Slatter, T.L., Ganesan,P., Holzhauer,C., Mehta,R., Rubio,C., Williams,G., Wilson,M., Royds, J.A., Baird, M.A., and Braithwaite, A.W. (2010). p53 mediated apoptosis prevents the accumulation of progenitor B-cells and B cell tumors: evidence from proline-rich domain deleted mice. Cell Death & Differ. 17, 540-550.

Heinlein, C., Deppert, W., Braithwaite, A.W., and Speidel, D. (2010).  A rapid and optimization-free procedure allows the in vivo detection of subtle cell cycle and ploidy alterations in tissues by flow cytometry. Cell Cycle 9. 3584-3590.

Nakagawa, S. & Schielzeth, H. (2010) Repeatability for Gaussian and non-Gaussian data: a practical guide for biologists. Biological Reviews. 85: 935-956

Coats, J., Poulin, R. & Nakagawa S. (2010) The consequences of parasitic infections for host behavioural correlations and repeatability. Behaviour. 147: 367-382.

Hadfield, J. D. & Nakagawa, S. (2010) General quantitative genetic methods for comparative biology: phylogenies, taxonomies and multi-trait models for continuous and categorical characters. Journal of Evolutionary Biology. 23: 494-508.

Lynch, J., McEwan, J., & Beck, C. W. (2010). Analysis of the expression of retinoic acid metabolising genes during Xenopus laevis organogenesis. Gene Expression Patterns, Advance Online Publication. doi: 10.1016/j.gep.2010.10.003

2009

Mönnich, M., Banks, S., Eccles, M., Dickinson, E. and Horsfield, J. (2009). Expression of cohesin and condensin genes during zebrafish development supports a non-proliferative role for cohesin. Gene Expr Patterns 9(8), 586-594

Jenkins ZA, van Kogelenberg M, Morgan T, Jeffs A, FukuzawaR, Pearl E, Thaller C, Hing AV, Porteous ME, Garcia-Miñaur S, Bohring A, Lacombe D, Stewart F, Fiskerstrand T, Bindoff L, Berland S, Adès L, Tchan M, David A, Wilson L, Hennekam R,Donnai D, Mansour S, Cormier-Daire V, Robertson SP (2009). Germline mutations in the tumor suppressor WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis. Nature Genetics 41: 95-100

Reversade B, Escande-Beillard N, Dimopoulou A, Fischer B, Chng C, Li Y, Shboul M, Tham P-Y, Kayserili H, Al-Gazali L, Shahwan M, Brancati F, Lee H, O'Connor BD, Schmidt-von Kegler M, Merriman B, Nelson SF, Masri A, Alkazaleh F, Guerra D, Ferrari P, Nanda A, Rajab A, Markie D, Gray M, Nelson J, Grix A, Sommer A, Savarirayan R, Janecke AR, Steichen E, Sillence D, Hauber, Budde IB, Nürnberg G, Nürnberg P, Seemann P, Kunkel D, Zambruno G, Dallapiccola B, Schuelke M, Robertson S, Hamamy H, Wollnik B, Van Maldergem L, Mundlos S, Kornak U (2009) Mutations in PYCR1 cause cutis laxa with progeroid features Nature Genetics 41(9):1016-21.

Fukuzawa R, Anaka MR, Weeks RJ, Morison IM, Reeve AE. Canonical WNT signalling determines lineage specificity in Wilms tumour  Oncogene 2009;28:1063-75.

Ledgerwood EC, Morison IM. Targeting the apoptosome for cancer therapy. Clinical Cancer Research 2009;15:420-424

Daniel White and Neil J. Gemmell, 2009. Can indirect tests detect a known recombination event in human mtDNA? Molecular Biology and Evolution 26:1435-1439.

Jiang, W-Q,  Zhong, Z-H, Nguyen, A., Henson, J.D., Toouli, C.D., Braithwaite, A.W., and Reddel, R.R.  (2009). Induction of ALT-associated PML bodies in telomerase-negative ALT cells by p53/p21-mediated growth arrest/senescence. J. Cell Biol. 185:  797-810.

Huschtscha, L.I., Moore, J.D., Noble, J.R., Campbell, H.G., Royds, J.A., Braithwaite, A.W., and Reddel, R.R. (2009).  Normal Human Mammary Epithelial Cells Proliferate Rapidly in the Presence of Elevated Levels of the Tumor Suppressors p53 and p21Cip1. J. Cell Sci. 122, 2989-2995.

Hancox, R.J., Poulton, R., Welch, D., Olova, N., McLachlan, C.R., Greene, J.R., Sears, M.R., Caspi, A., Moffitt, T.E., Robertson, S.P, and Braithwaite, A.W. (2009). Accelerated decline in lung function in cigarette smokers is associated with TP53/HDM2 polymorphisms. Hum. Genet. 126, 559-565.

Chapman, J. R., Nakagawa, S., Coltman, D. W., Slate, J. & Sheldon, B. C. (2009) A quantitative review of heterozygosity-fitness correlations in animal populations. Molecular Ecology. 18: 2746-2765.

Jeffs A, Glover AC, Slobbe LJ, Wang L, He S, Hazlett JA Awasthi A, Woolley AG, Marshall ES, Joseph WR, Print CG, Baguley BC and Eccles MR (2009). A gene expression signature of invasion in metastatic melanoma cells. PLoS One Dec 24;4(12):e8461.

Cohen SB, Ma W, Valova VA, Algie M, Harfoot R, Woolley AG , Robinson PJ & Braithwaite AW (2009) Genotoxic stress-induced nuclear translocation of oncoprotein YB-1 in the absence of proteolytic processing. Oncogene. 29(3):403-10.

Sheard, PW, Bewick, GS, Woolley, AG. Shaw, J, Fisher, L Fong, S & Duxson, MJ. (2009) Investigation of Neuromuscular Abnormalities in Neurotrophin-3 deficient mice. European J of Neuroscience 31(1):29-41.

Barker, D. M., & Beck, C. W. (2009). Overexpression of the transcription factor msx1 is insufficient to drive complete regeneration of refractory stage Xenopus laevis hindlimbs. Developmental Dynamics, 238(6), 1366-1378. doi: 10.1002/dvdy.21923

Beck, C. W., Izpisúa Belmonte, J. C., & Christen, B. (2009). Beyond early development: Xenopus as an emerging model for the study of regenerative mechanisms. Developmental Dynamics, 238(6), 1226-1248. doi: 10.1002/dvdy.21890

Malloch, E. L., Perry, K. J., Fukui, L., Johnson, V. R., Wever, J., Beck, C. W., King, M. W., & Henry, J. J. (2009). Gene expression profiles of lens regeneration and development in Xenopus laevis. Developmental Dynamics, 238(9), 2340-2356. doi: 10.1002/dvdy.21998

2008

BicknellLS, PittJ, AftimosS, Ramadas R, MawMA, Robertson SP (2008). A missense mutation in ALDH18A1, encoding D1-pyrroline-5-carboxylate synthase (P5CS), causes an autosomal recessive neurocutaneous syndrome. Eur J Hum Genet 16(10):1176-86

van Roij MHH, Mizumoto S, Yamada S, Morgan T, Tan-Sindhunata MB, . Meijers-Heijboer H, Verbeke JI, Markie D, Sugahara K, Robertson SP (2008). Spondyloepiphyseal dysplasia, Omani type: further definition of the phenotype. Amer J Med Genet 146A(18):2376-84

Fukuzawa R, Anaka AR, Heathcott RW, McNoe LA, Morison IM, Perlman EJ, Reeve AE. Wilms tumour histology is determined by distinct types of precursor lesions and not epigenetic changes. Journal of Pathology. 2008;215:377–387

Krueger C, Morison IM. Random monoallelic expression – making a choice. Trends in Genetics 2008;24:257-259

Morison IM, Cramer EM, Cheesman EJ, Cheong PL, Holyoake AJ, Fichelson S, Weeks RJ, Lo A, Davies SMK, Wilbanks SM, Fagerlund RD, Ludgate MW, da Silva Tatley FM, Coker A, Bocket NA, Hughes G, Pippig DA, Smith MP, Capron C, Ledgerwood EC. A mutation of human cytochrome c enhances the intrinsic apoptotic pathway but only causes thrombocytopenia. Nature Genetics 2008;40:387-389

Patrice C. Rosengrave, Neil J. Gemmell, Victoria J. Metcalf, Katherine P. McBride, and Robert Montgomerie, 2008. A mechanism for cryptic female choice in chinook salmon. Behavioural Ecology 19:1179–1185.

Mikael Brandström, Andrew T.M. Bagshaw, Neil J. Gemmell, and Hans Ellegren, 2008. The relationship between microsatellite polymorphism and recombination hot spots in the human genome. Molecular Biology and Evolution 25:2579–2587.

Daniel White, Jonci N. Wolff, Melanie Pierson and Neil J. Gemmell, 2008. Revealing the hidden complexities of mtDNA inheritance. Molecular Ecology 17:4925–4942.

Wesley C. Warren…, Neil J. Gemmell et al., 2008. Genome analysis of the platypus reveals unique signatures of evolution. Nature 453:175-184.

Chen, Y-J., Campbell, H.G., Wiles, A.K., Eccles, M.R., Reddel, R.R., Braithwaite, A.W., and Royds, J.R.  (2008). Pax8 regulates telomerase reverse transcriptase and telomerase RNA component in glioma. Cancer Res. 68:  5724-5732

Nakagawa, S. & Freckelton, R. P. (2008) Missing inaction: the danger of ignoring missing data. Trends in Ecology & Evolution. 11: 592-596

Woolley, AG, Tait, KJ, Hurren, BJ, Fisher, L, Sheard, P.W., & Duxson, M.J. (2008) Developmental loss of NT-3 in vivo results in reduced levels of myelin-specific proteins, a reduced extent of myelination and increased apoptosis of Schwann cells. GLIA 56:306–317

Pearl, E. J., Barker, D., Day, R. C., & Beck, C. W. (2008). Identification of genes associated with regenerative success of Xenopus laevis hindlimbs. BMC Developmental Biology, 8, 66. doi: 10.1186/1471-213X-8-66

2007

Horsfield, J. A., Anagnostou, S., Hu, J. Cho, K., Geisler, R., Lieschke, G., Crosier, K. E. and Crosier, P. S. (2007) Cohesin-dependent regulation of Runx genes. Development, 134(14), 2639-2649.

Antoine Fouquet, André Gilles, Miguel Vences, Christian Marty, Michel Blanc, and Neil J. Gemmell, 2007. Underestimation of species richness in Neotropical frogs revealed by mtDNA analyses. PLoS ONE 2: e1109.

Nakagawa, S. & Cuthill, I. (2007) Effect size, confidence interval and statistical significance: a practical guide for biologists. Biological Reviews. 82: 591-605.

Nakagawa, S., Gillespie, D. O. S., Hatchwell, B. J. & Burke T. (2007) Predictable males and unpredictable females: sex difference in repeatability of care in a wild bird population. Journal of Evolutionary Biology. 20: 1674-1681.

Jarikji, Z. H., Vanamala, S., Beck, C. W., Wright, C. V. E., Leach, S. D., & Horb, M. E. (2007). Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas. Developmental Biology, 304, 786-799.

2006

RobertsonSP, ThompsonS, MorganT, Holder-Espinasse M, Martinot-Duquenoy V, Wilkie AOM, Manouvrier-Hanu S. (2006). Post-zygotic mutation and germline mosaicism in the otopalatodigital syndrome spectrum disorders. Eur J Hum Genet 14:549-554

Bicknell LS, Farrington-Rock C, Shafeghati Y, Rump P, Alanay Y, Alembik Y, Al-Madani N, Firth H, Hassan Karimi-Nejad M, Kim CA, Leask K, Maisenbacher M, Moran E, Pappas JG, Prontera P, de Ravel T, Fryns JP, Sweeney E, Fryer A,Unger S, Wilson LC, Lachman RS, Rimoin DL, Cohn DH, Krakow DK, Robertson SP (2006). A Molecular and Clinical Study of Larsen Syndrome Caused By Mutations in FLNB. J Med Genet 44;89-98

Weeks RJ, Morison IM. Detailed methylation analysis of CpG islands on human chromosome region 9p21. Genes Chromosome Cancer 2006;45:357-64

Cutfield WS, Hofman PL, Mitchell M, Morison IM Could epigenetics play a role in the developmental origins of health and disease? Pediatric Research 2007;61(5 Pt 2): 68R–75R

Chen, Y.J., Hakin-Smith, V., Teo, M., Xinarianos, G.E., Jelinek, D.A., Carroll, T., McDowell, D., MacFarlane, M.R., Boet, R., Baguley, B.C., Braithwaite, A.W., Reddel, R.R., and Royds, J.A.  (2006). Association of mutant TP53 with alternative lengthening of telomeres and favorable prognosis in glioma. Cancer Res. 66:  6473-6476.

Beck, C. W., Christen, B., Barker, D., & Slack, J. M. W. (2006). Temporal requirement for bone morphogenetic proteins in regeneration of the tail and limb of Xenopus tadpoles. Mechanisms of Development, 123, 674-688.

Back to top